Search Results - "van den Bosch, Bianca JC"

Potential added value of combined DPYD/DPD genotyping and phenotyping to prevent severe toxicity in patients with a DPYD variant and decreased dihydropyrimidine dehydrogenase enzyme activity by Ockeloen, Charlotte W, Raaijmakers, Aron, Hijmans-van der Vegt, Manon, Bierau, Jörgen, de Vos-Geelen, Judith, Willemsen, Annelieke ECAB, van den Bosch, Bianca JC, Coenen, Marieke JH

“…Decreased dihydropyrimidine dehydrogenase enzyme activity is associated with severe fluoropyrimidine-associated toxicity. Four clinically relevant variants in…”
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Pharmacogenetics of inflammatory bowel disease by van den Bosch, Bianca Jc, Coenen, Marieke Jh

“…Patients with inflammatory bowel disease (IBD) show large variability in disease course, and also treatment response. The variability in treatment response has…”
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Riboflavin-responsive oxidative phosphorylation complex I deficiency caused by defective ACAD9: new function for an old gene by GERARDS, Mike, VAN DEN BOSCH, Bianca J. C, PROKISCH, Holger, RÖTIG, Agnès, DE COO, Irenaeus F. M, SMELTS, Hubert J. M, DANHAUSER, Katharina, SERRE, Valérie, VAN WEEGHEL, Michel, WANDERS, Ronald J. A, NICOLAES, Gerry A. F, SLUITER, Wim, SCHOONDERWOERD, Kees, SCHOLTE, Hans R

“…Mitochondrial complex I deficiency is the most common oxidative phosphorylation defect. Mutations have been detected in mitochondrial and nuclear genes, but…”
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Differences in Strength and Timing of the mtDNA Bottleneck between Zebrafish Germline and Non-germline Cells by Otten, Auke B.C., Theunissen, Tom E.J., Derhaag, Josien G., Lambrichs, Ellen H., Boesten, Iris B.W., Winandy, Marie, van Montfoort, Aafke P.A., Tarbashevich, Katsiaryna, Raz, Erez, Gerards, Mike, Vanoevelen, Jo M., van den Bosch, Bianca J.C., Muller, Marc, Smeets, Hubert J.M.

“…We studied the mtDNA bottleneck in zebrafish to elucidate size, timing, and variation in germline and non-germline cells. Mature zebrafish oocytes contain, on…”
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