Search Results - "van den Beucken, J. J. J. P."

Combinatorial Surface Roughness Effects on Osteoclastogenesis and Osteogenesis by Zhang, Yang, Chen, S. Elisa, Shao, Jinlong, van den Beucken, Jeroen J. J. P

“…Implant surface properties are a key factor in bone responses to metallic bone implants. In view of the emerging evidence on the important role of osteoclasts…”
Get full text

Bioactive Electrospun Scaffolds Delivering Growth Factors and Genes for Tissue Engineering Applications by Ji, Wei, Sun, Yan, Yang, Fang, van den Beucken, Jeroen J. J. P., Fan, Mingwen, Chen, Zhi, Jansen, John A.

“…ABSTRACT A biomaterial scaffold is one of the key factors for successful tissue engineering. In recent years, an increasing tendency has been observed toward…”
Get full text

Biomaterial‐based possibilities for managing peri‐implantitis by de Avila, Erica D., Oirschot, Bart A., van den Beucken, Jeroen J. J. P.

“…Peri‐implantitis is an inflammatory disease of hard and soft tissues around osseointegrated implants, followed by a progressive damage of alveolar bone. Oral…”
Get full text

Evaluation of polydimethylsiloxane‐based substrates for in vitro culture of human periodontal ligament cells by Yan, Xiang‐Zhen, Beucken, Jeroen J. J. P., Yuan, Chunxue, Jansen, John A., Yang, Fang

“…Periodontal ligament (PDL) cells are regarded as the cell type with the highest potential for periodontal regeneration. Biophysical cues of the culture…”
Get full text

Polyethylene glycol precipitation is an efficient method to obtain extracellular vesicle-depleted fetal bovine serum by Wang, Peng, Arntz, Onno J, Husch, Johanna F A, Kraan P M, Van der, Beucken, Jeroen J J P van den, van de Loo, Fons A J

“…Mesenchymal stromal/stem cell derived-extracellular vesicles (MSC-EVs) have gained interest as drug delivery nanoparticles, having immunoregulatory and…”
Get full text

Upscaling Osteoclast Generation by Enhancing Macrophage Aggregation Using Hollow Microgels by Husch, Johanna F.A., Araújo‐Gomes, Nuno, Willemen, Niels G.A., Cofiño‐Fabrés, Carla, van Creij, Nils, Passier, Robert, Leijten, Jeroen, van den Beucken, Jeroen J. J. P.

“…Osteoclasts, the bone resorbing cells of hematopoietic origin formed by macrophage fusion, are essential in bone health and disease. However, in vitro research…”
Get full text

Alendronate release from calcium phosphate cement for bone regeneration in osteoporotic conditions by van Houdt, Claire I. A., Gabbai-Armelin, Paulo R., Lopez-Perez, Paula M., Ulrich, Dietmar J. O., Jansen, John A., Renno, Ana Claudia M., van den Beucken, Jeroen J. J. P.

“…Osteoporosis represents a major health problem in terms of compromising bone strength and increasing the risk of bone fractures. It can be medically treated…”
Get full text

Preclinical evaluation of platinum-loaded hydroxyapatite nanoparticles in an embryonic zebrafish xenograft model by Nadar, Robin A, Asokan, Nandini, Degli Esposti, Lorenzo, Curci, Alessandra, Barbanente, Alessandra, Schlatt, Lukas, Karst, Uwe, Iafisco, Michele, Margiotta, Nicola, Brand, Michael, van den Beucken, Jeroen J J P, Bornhäuser, Martin, Leeuwenburgh, Sander C G

“…Hydroxyapatite (HA) nanoparticles are commonly used as building blocks in the design of bone-substituting biomaterials. Recently, these nanoparticles have been…”
Get more information

Regenerating Critical Size Rat Segmental Bone Defects with a Self‐Healing Hybrid Nanocomposite Hydrogel: Effect of Bone Condition and BMP‐2 Incorporation by Houdt, Claire I. A., Koolen, Marianne K. E., Lopez‐Perez, Paula M., Ulrich, Dietmar J. O., Jansen, John A., Leeuwenburgh, Sander C. G., Weinans, Harrie H., Beucken, Jeroen J. J. P.

“…The aim of the current study is to assess the biological performance of self‐healing hydrogels based on calcium phosphate (CaP) nanoparticles and…”
Get full text

Influence of bisphosphonate treatment on bone substitute performance in osteoporotic conditions by Camargo, Winston Adam, Hoekstra, Jan Willem, Jansen, John A., Beucken, Jeroen J. J. P.

“…Objective Considering the elevated number of osteoporotic patients in need of bone graft procedures, we here evaluated the effect of alendronate (ALN)…”
Get full text

Targeting of radioactive platinum-bisphosphonate anticancer drugs to bone of high metabolic activity by Nadar, Robin A., Farbod, Kambiz, der Schilden, Karlijn Codee-van, Schlatt, Lukas, Crone, Barbara, Asokan, Nandini, Curci, Alessandra, Brand, Michael, Bornhaeuser, Martin, Iafisco, Michele, Margiotta, Nicola, Karst, Uwe, Heskamp, Sandra, Boerman, Otto C., van den Beucken, Jeroen J. J. P., Leeuwenburgh, Sander C. G.

“…Platinum-based chemotherapeutics exhibit excellent antitumor properties. However, these drugs cause severe side effects including toxicity, drug resistance,…”
Get full text

Tough and injectable fiber reinforced calcium phosphate cement as an alternative to polymethylmethacrylate cement for vertebral augmentation: a biomechanical study by de Lacerda Schickert, Sónia, Pinto, João Castro, Jansen, John, Leeuwenburgh, Sander C G, van den Beucken, Jeroen J J P

“…Vertebral compression fractures (VCFs) are a very common problem among the elderly, which ultimately result in severe pain and a drastically reduced quality of…”
Get more information

Repair of complex ovine segmental mandibulectomy utilizing customized tissue engineered bony flaps by Watson, Emma, Pearce, Hannah A, Hogan, Katie J, van Dijk, Natasja W M, Smoak, Mollie M, Barrios, Sergio, Smith, Brandon T, Tatara, Alexander M, Woernley, Timothy C, Shum, Jonathan, Pearl, Craig B, Melville, James C, Ho, Tang, Hanna, Issa A, Demian, Nagi, van den Beucken, Jeroen J J P, Jansen, John A, Wong, Mark E, Mikos, Antonios G

“…Craniofacial defects require a treatment approach that provides both robust tissues to withstand the forces of mastication and high geometric fidelity that…”
Get full text

Periodontal regeneration via chemoattractive constructs by Cai, Xinjie, Yang, Fang, Walboomers, X. Frank, Wang, Yining, Jansen, John A., Beucken, Jeroen J. J. P., Plachokova, Adelina S.

“…Aim Chemoattractants, such as stromal cell‐derived factor‐1α (SDF‐1α), can offer an advantage for periodontal regeneration by recruiting the patient’s own stem…”
Get full text

Platinum-loaded, selenium-doped hydroxyapatite nanoparticles selectively reduce proliferation of prostate and breast cancer cells co-cultured in the presence of stem cells by Barbanente, Alessandra, Nadar, Robin A, Esposti, Lorenzo Degli, Palazzo, Barbara, Iafisco, Michele, van den Beucken, Jeroen J J P, Leeuwenburgh, Sander C G, Margiotta, Nicola

“…Chemotherapeutic treatment of patients with bone tumors or bone metastases often leads to severe side effects such as high drug toxicity, lack of tumor…”
Get more information

Calcium phosphate/poly(d,l-lactic-co-glycolic acid) composite bone substitute materials: evaluation of temporal degradation and bone ingrowth in a rat critical-sized cranial defect by van de Watering, Floor C. J., van den Beucken, Jeroen J. J. P., Walboomers, X. Frank, Jansen, John A.

“…Objectives: The present study aimed to provide temporal information on material degradation and bone formation using composite (C) bone defect filler materials…”
Get full text

Evaluation of the inflammatory responses to sol–gel coatings with distinct biocompatibility levels by Cerqueira, Andreia, Araújo‐Gomes, Nuno, Zhang, Yang, Beucken, Jeroen J. J. P., Martínez‐Ramos, Cristina, Ozturan, Seda, Izquierdo, Raúl, Muriach, María, Romero‐Cano, Ricard, Baliño, Pablo, Romero‐Gavilán, Francisco J.

“…The immune system plays a crucial role in determining the implantation outcome, and macrophages are in the frontline of the inflammatory processes. Further,…”
Get full text

Long-term evaluation of the degradation behavior of three apatite-forming calcium phosphate cements by An, Jie, Liao, Hongbing, Kucko, Nathan W., Herber, Ralf-Peter, Wolke, Joop G. C., van den Beucken, Jeroen J. J. P., Jansen, John A., Leeuwenburgh, Sander C. G.

“…Calcium phosphate cements (CPCs) are injectable bone substitutes with a long clinical history because of their biocompatibility and osteoconductivity…”
Get full text

Histological and Histomorphometric Analyses of Bone Regeneration in Osteoporotic Rats Using a Xenograft Material by Shaheen, Marwa Y, Basudan, Amani M, Niazy, Abdurahman A, van den Beucken, Jeroen J J P, Jansen, John A, Alghamdi, Hamdan S

“…We evaluated the effect of osteoporotic induction after eight weeks of initial healing of bone defects grafted with a xenograft material in a rat model. Bone…”
Get full text

Multimodal pore formation in calcium phosphate cements by Lodoso‐Torrecilla, Irene, van Gestel, Nicole A. P., Diaz‐Gomez, Luis, Grosfeld, Eline‐Claire, Laperre, Kjell, Wolke, Joop G. C., Smith, Brandon T., Arts, Jacobus J., Mikos, Antonios G., Jansen, John A., Hofmann, Sandra, van den Beucken, Jeroen J. J. P.

“…Calcium phosphate cements (CPCs) are commonly used as bone substitute materials. However, their slow degradation rate and lack of macroporosity hinders new…”
Get full text