Search Results - "van den Bersselaar, Liduine A"

Alteration of the intestinal microbiome characterizes preclinical inflammatory arthritis in mice and its modulation attenuates established arthritis by Rogier, Rebecca, Evans-Marin, Heather, Manasson, Julia, van der Kraan, Peter M., Walgreen, Birgitte, Helsen, Monique M., van den Bersselaar, Liduine A., van de Loo, Fons A., van Lent, Peter L., Abramson, Steven B., van den Berg, Wim B., Koenders, Marije I., Scher, Jose U., Abdollahi-Roodsaz, Shahla

“…Perturbations of the intestinal microbiome have been observed in patients with new-onset and chronic autoimmune inflammatory arthritis. However, it is…”
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Periodontal pathogens directly promote autoimmune experimental arthritis by inducing a TLR2- and IL-1-driven Th17 response by de Aquino, Sabrina G, Abdollahi-Roodsaz, Shahla, Koenders, Marije I, van de Loo, Fons A J, Pruijn, Ger J M, Marijnissen, Renoud J, Walgreen, Birgitte, Helsen, Monique M, van den Bersselaar, Liduine A, de Molon, Rafael S, Avila Campos, Mario J, Cunha, Fernando Q, Cirelli, Joni A, van den Berg, Wim B

“…Increasing epidemiologic evidence supports a link between periodontitis and rheumatoid arthritis. The actual involvement of periodontitis in the pathogenesis…”
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Destructive role of myeloid differentiation factor 88 and protective role of TRIF in interleukin-17-dependent arthritis in mice by Abdollahi-Roodsaz, Shahla, van de Loo, Fons A. J., Koenders, Marije I., Helsen, Monique M., Walgreen, Birgitte, van den Bersselaar, Liduine A., Arntz, Onno J., Takahashi, Nozomi, Joosten, Leo A. B., van den Berg, Wim B.

“…Objective Increasing evidence indicates the involvement of Toll‐like receptors (TLRs) in the progression of arthritis; however, the contribution of the two…”
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Interleukin-18 Promotes Joint Inflammation and Induces Interleukin-1-Driven Cartilage Destruction by Joosten, Leo A.B., Smeets, Ruben L., Koenders, Marije I., van den Bersselaar, Liduine A.M., Helsen, Monique M.A., Oppers-Walgreen, Birgitte, Lubberts, Erik, Iwakura, Yoichiro, van de Loo, Fons A.J., van den Berg, Wim B.

“…Interleukin (IL)-18 is a member of the IL-1 family of proteins that exerts proinflammatory effects and is a pivotal cytokine for the development of Th1…”
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Shift from toll‐like receptor 2 (TLR‐2) toward TLR‐4 dependency in the erosive stage of chronic streptococcal cell wall arthritis coincident with TLR‐4–mediated interleukin‐17 production by Abdollahi‐Roodsaz, Shahla, Joosten, Leo A. B., Helsen, Monique M., Walgreen, Birgitte, van Lent, Peter L., van den Bersselaar, Liduine A., Koenders, Marije I., van den Berg, Wim B.

“…Objective Toll‐like receptors (TLRs) may activate innate and adaptive immune responses in rheumatoid arthritis (RA) through recognition of microbial as well as…”
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Toll‐like Receptor 2 Controls Acute Immune Complex–Driven Arthritis in Mice by Regulating the Inhibitory Fcγ Receptor IIB by Abdollahi‐Roodsaz, Shahla, Koenders, Marije I., Walgreen, Birgitte, Bolscher, Judith, Helsen, Monique M., den Bersselaar, Liduine A., Lent, Peter L., de Loo, Fons A. J., den Berg, Wim B.

“…Objective Previous studies have demonstrated a protective role of Toll‐like receptor 2 (TLR‐2) and a proinflammatory function of TLR‐4 during chronic T…”
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T cell dependence of chronic destructive murine arthritis induced by repeated local activation of toll‐like receptor–driven pathways: Crucial role of both interleukin‐1β and interleukin‐17 by Joosten, Leo A. B., Abdollahi‐Roodsaz, Shahla, Heuvelmans‐Jacobs, Marleen, Helsen, Monique M. A., van den Bersselaar, Liduine A. M., Oppers‐Walgreen, Birgitte, Koenders, Marije I., van den Berg, Wim B.

“…Objective The pathogenesis of rheumatoid arthritis is often linked to bacterial infections. The present study was undertaken to develop a mouse model of…”
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Association of interleukin‐18 expression with enhanced levels of both interleukin‐1β and tumor necrosis factor α in knee synovial tissue of patients with rheumatoid arthritis by Joosten, Leo A. B., Radstake, Timothy R. D., Lubberts, Erik, van den Bersselaar, Liduine A. M., van Riel, Piet L. C. M., van Lent, Peter L. E. M., Barrera, Pilar, van den Berg, Wim B.

“…Objective To examine the expression patterns of interkeukin‐18 (IL‐18) in synovial biopsy tissue of patients with rheumatoid arthritis (RA), and to determine…”
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T cell dependence of chronic destructive murine arthritis induced by repeated local activation of Toll-like receptor-driven pathways: crucial role of both interleukin-1beta and interleukin-17 by Joosten, Leo A B, Abdollahi-Roodsaz, Shahla, Heuvelmans-Jacobs, Marleen, Helsen, Monique M A, van den Bersselaar, Liduine A M, Oppers-Walgreen, Birgitte, Koenders, Marije I, van den Berg, Wim B

“…The pathogenesis of rheumatoid arthritis is often linked to bacterial infections. The present study was undertaken to develop a mouse model of chronic…”
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Reduction of interleukin‐17–induced inhibition of chondrocyte proteoglycan synthesis in intact murine articular cartilage by interleukin‐4 by Lubberts, Erik, Joosten, Leo A. B., Van De Loo, Fons A. J., Van Den Bersselaar, Liduine A. M., Van Den Berg, Wim B.

“…Objective To investigate the role of interleukin‐4 (IL‐4) and IL‐10 in basal and IL‐1– and IL‐17–mediated inhibition of chondrocyte metabolism. Methods…”
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Association of interleukin-18 expression with enhanced levels of both interleukin-1beta and tumor necrosis factor alpha in knee synovial tissue of patients with rheumatoid arthritis by Joosten, Leo A B, Radstake, Timothy R D, Lubberts, Erik, van den Bersselaar, Liduine A M, van Riel, Piet L C M, van Lent, Peter L E M, Barrera, Pilar, van den Berg, Wim B

“…To examine the expression patterns of interkeukin-18 (IL-18) in synovial biopsy tissue of patients with rheumatoid arthritis (RA), and to determine whether…”
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Association of interleukin-18 expression with enhanced levels of both interleukin-1β and tumor necrosis factor a in knee synovial tissue of patients with rheumatoid arthritis by JOOSTEN, Leo A. B, RADSTAKE, Timothy R. D, LUBBERTS, Erik, VAN DEN BERSSELAAR, Liduine A. M, VAN RIEL, Piet L. C. M, VAN LENT, Peter L. E. M, BARRERA, Pilar, VAN DEN BERG, Wim B

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