Search Results - "van den Berkmortel, F"
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Role of multidisciplinary team meetings in implementation of chemohormonal therapy in metastatic prostate cancer in daily practice
Published in Prostate cancer and prostatic diseases (01-03-2023)“…Background The recommended treatment for a subset of patients with metastatic prostate cancer (mPC) changed from androgen deprivation therapy (ADT) to…”
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Improved survival for sequentially as opposed to concurrently delivered neoadjuvant chemotherapy in non-metastatic breast cancer
Published in Breast cancer research and treatment (01-10-2017)“…Purpose The INTENS study was designed to determine whether delivering neoadjuvant chemotherapy at a higher dose in a shorter period of time improves outcome of…”
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Early discontinuation of PD-1 blockade upon achieving a complete or partial response in patients with advanced melanoma: the multicentre prospective Safe Stop trial
Published in BMC cancer (25-03-2021)“…The introduction of programmed cell death protein 1 (PD-1) blockers (i.e. nivolumab and pembrolizumab) has significantly improved the prognosis of patients…”
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Safe Stop IPI-NIVO trial: early discontinuation of nivolumab upon achieving a complete or partial response in patients with irresectable stage III or metastatic melanoma treated with first-line ipilimumab-nivolumab - study protocol
Published in BMC cancer (23-05-2024)“…Patients with irresectable stage III or metastatic melanoma presenting with poor prognostic factors are usually treated with a combination of immune checkpoint…”
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Seasonal variation of anti‐PD‐1 outcome in melanoma—Results from a Dutch patient cohort
Published in Pigment cell and melanoma research (01-01-2024)“…Despite the improved survival rates of patients with advanced stage melanoma since the introduction of ICIs, many patients do not have (long‐term) benefit from…”
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Trends in survival and costs in metastatic melanoma in the era of novel targeted and immunotherapeutic drugs
Published in ESMO open (01-12-2021)“…The objective of this study was to evaluate trends in survival and health care costs in metastatic melanoma in the era of targeted and immunotherapeutic drugs…”
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A real-life study on the implementation and effectiveness of exemestane plus everolimus per hospital type in patients with advanced breast cancer. A study of the Southeast Netherlands Advanced Breast Cancer registry
Published in Breast (Edinburgh) (01-04-2019)“…We aimed to assess the implementation and effectiveness of exemestane plus everolimus treatment per hospital type in real-life, shortly after approval of…”
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The effect of cholesterol lowering on carotid and femoral artery wall stiffness and thickness in patients with familial hypercholesterolaemia
Published in European journal of clinical investigation (01-06-2000)“…Background Early in the process of atherosclerosis, changes in vessel wall stiffness and thickness may occur. The present study evaluates the effect of…”
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Associations between the Geriatric-8 and 4-meter gait speed test and subsequent delivery of adjuvant chemotherapy in older patients with colon cancer
Published in Journal of geriatric oncology (01-11-2021)“…Feasible screening methods are important to identify older patients who might benefit from adjuvant chemotherapy. The aim of this study was to investigate the…”
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Prognosis of metastatic breast cancer: are there differences between patients with de novo and recurrent metastatic breast cancer?
Published in British journal of cancer (28-04-2015)“…Background: We aimed to determine the prognostic impact of time between primary breast cancer and diagnosis of distant metastasis (metastatic-free interval,…”
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Progressive arterial wall stiffening in patients with increasing diastolic blood pressure
Published in Journal of human hypertension (01-10-2001)“…Hypertension is an established risk factor for cardiovascular disease. Risk factor patterns for various cardiovascular complications are different. We studied…”
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In real life, one-quarter of patients with hormone receptor-positive metastatic breast cancer receive chemotherapy as initial palliative therapy: a study of the Southeast Netherlands Breast Cancer Consortium
Published in Annals of oncology (01-02-2016)“…The objective of this study was to present initial systemic treatment choices and the outcome of hormone receptor-positive (HR+) metastatic breast cancer. All…”
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Adjuvant immunotherapy in older patients with stage III and resected stage IV melanoma: Toxicity and recurrence-free survival outcomes from the Dutch melanoma treatment registry
Published in European journal of cancer (1990) (01-11-2024)“…Adjuvant anti-PD-1 therapy improves relapse free survival in stage III melanoma, but also leads to immune-related adverse events (irAEs). Older patients are of…”
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Survival outcomes of patients with advanced melanoma from 2013 to 2017: Results of a nationwide population-based registry
Published in European journal of cancer (1990) (01-02-2021)“…The treatment landscape has completely changed for advanced melanoma. We report survival outcomes and the differential impact of prognostic factors over time…”
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Smoking or its cessation does not alter the susceptibility to in vitro LDL oxidation
Published in European journal of clinical investigation (01-11-2000)“…Background Enhanced induction of low density lipoprotein (LDL) oxidation may play a role in the increased cardiovascular risk in smokers. We determined LDL…”
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Urinary incontinence and erectile dysfunction in patients with localized or locally advanced prostate cancer: A nationwide observational study
Published in Urologic oncology (01-09-2020)“…•Population-based studies on functional outcomes after prostate cancer treatment are scarce.•15% of prostatectomy patients reported urinary incontinence 24…”
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Survival of stage IV melanoma in Belgium and the Netherlands
Published in Journal of the European Academy of Dermatology and Venereology (01-02-2022)Get full text
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Real-world and trial-based cost-effectiveness analysis of bevacizumab in HER2-negative metastatic breast cancer patients: a study of the Southeast Netherlands Breast Cancer Consortium
Published in European journal of cancer (1990) (01-07-2017)“…Abstract Introduction The aim of our analysis was to assess the real-world cost-effectiveness of bevacizumab in addition to taxane treatment versus taxane…”
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Comparison of two neoadjuvant chemoradiotherapy regimens in patients with potentially curable esophageal carcinoma
Published in Diseases of the esophagus (01-05-2014)“…Summary The implementation of neoadjuvant chemoradiotherapy (CRT) in esophageal cancer (EC) patients has led to improved survival rates. Worldwide, different…”
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