Search Results - "van den Berg, Sara P. H."
-
1
Quantification of T-cell dynamics during latent cytomegalovirus infection in humans
Published in PLoS pathogens (01-12-2021)“…Cytomegalovirus (CMV) infection has a major impact on the T-cell pool, which is thought to be associated with ageing of the immune system. The effect on the…”
Get full text
Journal Article -
2
Killer cell proteases can target viral immediate-early proteins to control human cytomegalovirus infection in a noncytotoxic manner
Published in PLoS pathogens (01-04-2020)“…Human cytomegalovirus (HCMV) is the most frequent viral cause of congenital defects and can trigger devastating disease in immune-suppressed patients…”
Get full text
Journal Article -
3
The hallmarks of CMV-specific CD8 T-cell differentiation
Published in Medical microbiology and immunology (01-08-2019)“…Upon cytomegalovirus (CMV) infection, large T-cell responses are elicited that remain high or even increase over time, a phenomenon named memory T-cell…”
Get full text
Journal Article -
4
Negative Effect of Age, but Not of Latent Cytomegalovirus Infection on the Antibody Response to a Novel Influenza Vaccine Strain in Healthy Adults
Published in Frontiers in immunology (29-01-2018)“…Older adults are more vulnerable to influenza virus infection and at higher risk for severe complications and influenza-related death compared to younger…”
Get full text
Journal Article -
5
CMV immune evasion and manipulation of the immune system with aging
Published in GeroScience (01-06-2017)“…Human cytomegalovirus (HCMV) encodes numerous proteins and microRNAs that function to evade the immune response and allow the virus to replicate and…”
Get full text
Journal Article -
6
Latent CMV Infection Is Associated With Lower Influenza Virus-Specific Memory T-Cell Frequencies, but Not With an Impaired T-Cell Response to Acute Influenza Virus Infection
Published in Frontiers in immunology (05-05-2021)“…Latent infection with cytomegalovirus (CMV) is assumed to contribute to the age-associated decline of the immune system. CMV induces large changes in the…”
Get full text
Journal Article -
7
A Phase 1/2a Study Evaluating Safety and Immunogenicity of Ad26.RSV.preF in RSV-seronegative Toddlers Aged 12–24 Months
Published in Open forum infectious diseases (01-09-2024)“…Abstract Background Respiratory syncytial virus (RSV) causes serious illness in children. The Ad26.RSV.preF vaccine candidate was immunogenic with acceptable…”
Get full text
Journal Article -
8
Limited effect of duration of CMV infection on adaptive immunity and frailty: insights from a 27‐year‐long longitudinal study
Published in Clinical & translational immunology (2020)“…Objectives Cytomegalovirus infection is thought to affect the immune system and to impact general health during ageing. Higher CMV‐specific antibody levels in…”
Get full text
Journal Article