Search Results - "van den Berg, Bastiaan A"
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Exploring sequence characteristics related to high-level production of secreted proteins in Aspergillus niger
Published in PloS one (01-10-2012)“…Protein sequence features are explored in relation to the production of over-expressed extracellular proteins by fungi. Knowledge on features influencing…”
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Journal Article -
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Insight into neutral and disease-associated human genetic variants through interpretable predictors
Published in PloS one (31-03-2015)“…A variety of methods that predict human nonsynonymous single nucleotide polymorphisms (SNPs) to be neutral or disease-associated have been developed over the…”
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Journal Article -
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SPiCE: a web-based tool for sequence-based protein classification and exploration
Published in BMC bioinformatics (31-03-2014)“…Amino acid sequences and features extracted from such sequences have been used to predict many protein properties, such as subcellular localization or…”
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4
Protein redesign by learning from data
Published in Protein engineering, design and selection (01-09-2014)“…Protein redesign methods aim to improve a desired property by carefully selecting mutations in relevant regions guided by protein structure. However, often…”
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Toward tunable RNA thermo-switches for temperature dependent gene expression
Published 25-09-2011“…RNA thermometers are mRNA strands with a temperature dependent secondary structure: depending on the spatial conformation, the mRNA strand can get translated…”
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Journal Article