Search Results - "van den Berg, Aafke"

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  1. 1

    Chromosome organization by one-sided and two-sided loop extrusion by Banigan, Edward J, van den Berg, Aafke A, Brandão, Hugo B, Marko, John F, Mirny, Leonid A

    Published in eLife (06-04-2020)
    “…SMC complexes, such as condensin or cohesin, organize chromatin throughout the cell cycle by a process known as loop extrusion. SMC complexes reel in DNA,…”
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    Journal Article
  2. 2

    Crowding-induced transcriptional bursts dictate polymerase and nucleosome density profiles along genes by van den Berg, Aafke A, Depken, Martin

    Published in Nucleic acids research (27-07-2017)
    “…During eukaryotic transcription, RNA polymerase (RNAP) translocates along DNA molecules covered with nucleosomes and other DNA binding proteins. Though the…”
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    Journal Article
  3. 3

    RNA polymerases as moving barriers to condensin loop extrusion by Brandão, Hugo B., Paul, Payel, vandenBerg, Aafke A., Rudner, David Z., Wang, Xindan, Mirny, Leonid A.

    “…To separate replicated sister chromatids during mitosis, eukaryotes and prokaryotes have structural maintenance of chromosome (SMC) condensin complexes that…”
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  4. 4

    Transcription shapes 3D chromatin organization by interacting with loop extrusion by Banigan, Edward J, Tang, Wen, van den Berg, Aafke A, Stocsits, Roman R, Wutz, Gordana, Brandão, Hugo B, Busslinger, Georg A, Peters, Jan-Michael, Mirny, Leonid A

    “…Cohesin folds mammalian interphase chromosomes by extruding the chromatin fiber into numerous loops. "Loop extrusion" can be impeded by chromatin-bound…”
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    Journal Article
  5. 5

    Probing the mechanism of nick searching by LIG1 at the single-molecule level by Chatterjee, Surajit, Chaubet, Loïc, van den Berg, Aafke, Mukhortava, Ann, Almohdar, Danah, Ratcliffe, Jacob, Gulkis, Mitchell, Çağlayan, Melike

    Published in Nucleic acids research (15-10-2024)
    “…DNA ligase 1 (LIG1) joins Okazaki fragments during the nuclear replication and completes DNA repair pathways by joining 3'-OH and 5'-PO4 ends of nick at the…”
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  6. 6

    Resolving the subtle details of human DNA alkyltransferase lesion search and repair mechanism by single-molecule studies by Kono, Sarah, van den Berg, Aafke, Simonetta, Marco, Mukhortava, Ann, Garman, Elspeth F, Tessmer, Ingrid

    “…SignificanceWe directly visualize DNA translocation and lesion recognition by the O -alkylguanine DNA alkyltransferase (AGT). Our data show bidirectional…”
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  7. 7

    Slow unloading leads to DNA-bound β2-sliding clamp accumulation in live Escherichia coli cells by Moolman, M. Charl, Krishnan, Sriram Tiruvadi, Kerssemakers, Jacob W. J., van den Berg, Aafke, Tulinski, Pawel, Depken, Martin, Reyes-Lamothe, Rodrigo, Sherratt, David J., Dekker, Nynke H.

    Published in Nature communications (18-12-2014)
    “…The ubiquitous sliding clamp facilitates processivity of the replicative polymerase and acts as a platform to recruit proteins involved in replication,…”
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  8. 8

    The 4D nucleome project by Dekker, Job, Belmont, Andrew S., Guttman, Mitchell, Leshyk, Victor O., Lis, John T., Lomvardas, Stavros, Mirny, Leonid A., O’Shea, Clodagh C., Park, Peter J., Ren, Bing, Politz, Joan C. Ritland, Shendure, Jay, Zhong, Sheng

    Published in Nature (London) (14-09-2017)
    “…The 4D Nucleome Network aims to develop and apply approaches to map the structure and dynamics of the human and mouse genomes in space and time with the goal…”
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  12. 12

    Single pairs of time-bin entangled photons by Versteegh, Marijn A. M, Reimer, Michael E, Berg, Aafke A. van den, Juska, Gediminas, Dimastrodonato, Valeria, Gocalinska, Agnieszka, Pelucchi, Emanuele, Zwiller, Val

    Published 07-07-2015
    “…Phys. Rev. A 92, 033802 (2015) Time-bin entangled photons are ideal for long-distance quantum communication via optical fibers. Here we present a source where,…”
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    Journal Article
  13. 13

    Slow unloading leads to DNA-bound [beta]2-sliding clamp accumulation in live Escherichia coli cells by Moolman, M Charl, Krishnan, Sriram Tiruvadi, Kerssemakers, Jacob W J, Van Den Berg, Aafke, Tulinski, Pawel, Depken, Martin, Reyes-lamothe, Rodrigo, Sherratt, David J, Dekker, Nynke H

    Published in Nature communications (01-12-2014)
    “…The ubiquitous sliding clamp facilitates processivity of the replicative polymerase and acts as a platform to recruit proteins involved in replication,…”
    Get full text
    Journal Article