Search Results - "van de Wiel, Paul"

Comparison of pathogen DNA isolation methods from large volumes of whole blood to improve molecular diagnosis of bloodstream infections by Loonen, Anne J M, Bos, Martine P, van Meerbergen, Bart, Neerken, Sigi, Catsburg, Arnold, Dobbelaer, Irene, Penterman, Roel, Maertens, Geert, van de Wiel, Paul, Savelkoul, Paul, van den Brule, Adriaan J C

“…For patients suffering from bloodstream infections (BSI) molecular diagnostics from whole blood holds promise to provide fast and adequate treatment. However,…”
Get full text

Principles of quantitation of viral loads using nucleic acid sequence-based amplification in combination with homogeneous detection using molecular beacons by Weusten, Jos J A M, Carpay, Wim M, Oosterlaken, Tom A M, van Zuijlen, Martien C A, van de Wiel, Paul A

“…For quantitative NASBA-based viral load assays using homogeneous detection with molecular beacons, such as the NucliSens EasyQ HIV-1 assay, a quantitation…”
Get full text

Stochastic processes defining sensitivity and variability of internally calibrated quantitative NASBA‐based viral load assays by Weusten, Jos J. A. M., Wouters, Pieter A. W. M., van Zuijlen, Martien C. A., van de Wiel, Paul A.

“…For quantitative assessment of virus particles in patient plasma samples various assays are commercially available. Typical performance characteristics for…”
Get full text

Selection of Personalized Patient Therapy through the Use of Knowledge-Based Computational Models That Identify Tumor-Driving Signal Transduction Pathways by VERHAEGH, Wim, VAN OOIJEN, Henk, VAN DE STOLPE, Anja, INDA, Márcia A, HATZIS, Pantelis, VERSTEEG, Rogier, SMID, Marcel, MARTENS, John, FOEKENS, John, VAN DE WIEL, Paul, CLEVERS, Hans

“…Increasing knowledge about signal transduction pathways as drivers of cancer growth has elicited the development of "targeted drugs," which inhibit aberrant…”
Get full text

Abstract A131: Fulvestrant resistance in an MCF-7 model for breast cancer is associated with complete loss of ER pathway activity and gain of MAPK-AP1 pathway activity by Wesseling-Rozendaal, Yvonne, Stolpe, Anja van de, Holtzer, Laurent, Inda, Marcia Alves de, Wiel, Paul van de

“…Abstract Background: 10-15 signal transduction pathways govern major cellular processes, e.g. cell division, differentiation and migration, both in physiology…”
Get full text

Genomic profiling of metastatic castration-resistant prostate cancer samples resistant to androgen-receptor pathway inhibitors by Menssouri, Naoual, Poiraudeau, Loic, Helissey, Carole, Bigot, Ludovic, Sabio, Jonathan, Ibrahim, Tony, Pobel, Cedric, Nicotra, Claudio, Ngo-Camus, Maud, Lacroix, Ludovic, Rouleau, Etienne, Tselikas, Lambros, Chauchereau, Anne, Blanc-Durand, Félix, Bernard-Tessier, Alice, Patrikidou, Anna, Naoun, Natacha, Flippot, Ronan, Colomba, Emeline, Fuerea, Alina, Albiges, Laurence, Lavaud, Pernelle, van de Wiel, Paul, den Biezen-Timmermans, Eveline, Wesseling-Rozendaal, Yvonne, Ponce-Aix, Santiago, Michiels, Stefan, Massard, Christophe, Gautheret, Daniel, Barlesi, Fabrice, Andre, Fabrice, Besse, Benjamin, Scoazec, Jean-Yves, Friboulet, Luc, Fizazi, Karim, Loriot, Yohann

“…The androgen receptor axis inhibitors (ARPI) (e.g, enzalutamide, abiraterone acetate) are administered in daily practice for men with metastatic…”
Get full text

Genomic Profiling of Metastatic Castration-Resistant Prostate Cancer Samples Resistant to Androgen Receptor Pathway Inhibitors by Menssouri, Naoual, Poiraudeau, Loïc, Helissey, Carole, Bigot, Ludovic, Sabio, Jonathan, Ibrahim, Tony, Pobel, Cédric, Nicotra, Claudio, Ngo-Camus, Maud, Lacroix, Ludovic, Rouleau, Etienne, Tselikas, Lambros, Chauchereau, Anne, Blanc-Durand, Félix, Bernard-Tessier, Alice, Patrikidou, Anna, Naoun, Natacha, Flippot, Ronan, Colomba, Emeline, Fuerea, Alina, Albiges, Laurence, Lavaud, Pernelle, van de Wiel, Paul, den Biezen, Eveline, Wesseling-Rozendaal, Yvonne, Ponce-Aix, Santiago, Michiels, Stefan, Massard, Christophe, Gautheret, Daniel, Barlesi, Fabrice, André, Fabrice, Besse, Benjamin, Scoazec, Jean-Yves, Friboulet, Luc, Fizazi, Karim, Loriot, Yohann

“…Abstract Purpose: The androgen receptor axis inhibitors (ARPI; e.g., enzalutamide, abiraterone acetate) are administered in daily practice for men with…”
Get full text

Abstract 1331: First results of the EIT PACMAN Study: OncoSignal pathway analysis to identify clinically actionable signal transduction pathway activity in a variety of cancer types by Martin-Romano, Patricia, Neerken, Sieglinde, Van de Stolpe, Anja, Den Biezen-Timmerman, Eveline, Ngo, Maud, Nicotra, Claudio, Akse, Martijn, Eggermont, Alexander, Van de Wiel, Paul, Massard, Christophe, Calvo, Fabien

“…Abstract Introduction: Precision medicine has shown to improve outcomes of cancer patients by identifying oncogenic alterations and actionable mutations. Yet,…”
Get full text

EIT PACMAN Study preliminary results: OncoSignal pathway analysis identifies actionable cancer targets by Martin, Patricia, Neerken, Sigi, Van De Stolpe, Anja, den Biezen-Timmermans, Eveline, Akse, Martijn, Ngocamus, Maud, Nicotra, Claudio, Eggermont, Alexander M., Van De Wiel, Paul, Massard, Christophe, Calvo, Fabien M.

“…Abstract only e15606 Background: Precision medicine refers to tailoring of treatment to each individual patient, although identifying tumor driving signaling…”
Get full text

Abstract PO5-13-10: Determining tumor-driving cell signaling pathways in breast cancer: Support for targeted therapy selection by Wiel, Paul van de, Wesseling-Rozendaal, Yvonne, Pierik, Anke, van Strijp, Dianne, Vermeer, Saskia, Tashrifwala, Fatema, Hartnett, Josette, Babkowski, Robert, Rose, Suzanne

“…Abstract Introduction: Success of therapeutic interventions largely rely on the pathological and biological characteristics of the tumor and varies due to the…”
Get full text

Abstract 5291: Prognosis within different breast cancer subtypes using functional activity of signaling pathways by van Ooijen, Henk, Inda, Márcia A., Hoffmann, Ralf, van de Wiel, Paul, van de Stolpe, Anja, Verhaegh, Wim

“…Abstract Introduction Gene signatures to assess prognosis of breast cancer patients are generally restricted to ER-positive/luminal breast cancers, and provide…”
Get full text

Efficient amplification with NASBA ® of hepatitis B virus, herpes simplex virus and methicillin resistant Staphylococcus aureus DNA by Deiman, Birgit, Jay, Corinne, Zintilini, Carine, Vermeer, Saskia, van Strijp, Dianne, Venema, Fokke, van de Wiel, Paul

“…A new mechanism is described for DNA amplification using nucleic acid sequence-based amplification (NASBA ®) including a restriction enzyme digestion and P1…”
Get full text

Modeling Power Supply Noise in Delay Testing by Jing Wang, Walker, D.M., Xiang Lu, Majhi, A., Kruseman, B., Gronthoud, G., Villagra, L.E., van de Wiel, P.J.A., Eichenberger, S.

“…Excessive power supply noise during test can cause overkill. This article discusses two models for supply noise in delay testing and their application to test…”
Get full text

Power Supply Noise in Delay Testing by Wang, Jing, H. Walker, D. M., Majhi, Ananta, Kruseman, Bram, Gronthoud, Guido, Villagra, Luis Elvira, van de Wiel, Paul, Eichenberger, Stefan

“…Excessive power supply noise can affect path delay and cause overkill during delay test. This paper presents low-cost noise models for fast power supply noise…”
Get full text

NIM- a noise index model to estimate delay discrepancies between silicon and simulation by Alpaslan, Elif, Dworak, Jennifer, Kruseman, Bram, Majhi, Ananta K, Heuvelman, Wilmar M, van de Wiel, Paul

“…As CMOS technology continues to scale, the accurate prediction of silicon timing through the use of pre-silicon modeling and analysis has become especially…”
Get full text

Macroscopic and microscopic early effects of tumour necrosis factor on murine Meth A sarcoma, and relation to curative activity by Van de Wiel, P A, Bloksma, N, Kuper, C F, Hofhuis, F M, Willers, J M

“…Mice with solid Meth A sarcoma in the skin received an intravenous or intralesional injection of graded doses of recombinant human tumour necrosis factor…”
Get more information

Role of tumor necrosis factor in the tumour-necrotizing activity of agents with diverging toxicity by VAN DE WIEL, P. A, VAN DER PIJL, A, BLOKSMA, N

“…We investigated the ability of various tumour-necrotizing agents with diverging toxicity to induce tumour necrosis factor (TNF) and cytostatic activity in…”
Get full text

Synergic action between tumor necrosis factor and endotoxins or poly(A.U) on cultured bovine endothelial cells by VAN DE WIEL, P. A, PIETERS, R. H. H, VAN DER PIJL, A, BLOKSMA, N

“…In order to investigate whether direct effects on tumor vasculature may contribute to induction of necrosis of solid tumors in vivo, agents and combinations…”
Get full text

Role of histamine in the antitumour activity of endotoxin by BLOKSMA, N, VAN DE WIEL, P, HOFHUIS, F, KUPER, F, WILLERS, J

“…The role of histamine in the antitumour activity of endotoxin against solid syngeneic Meth-A sarcoma in BALB/c mice was studied. Endotoxin induces haemorrhagic…”
Get full text

O-polysaccharide-protein conjugates induce high levels of specific antibodies to Pseudomonas aeruginosa immunotype 3 lipopolysaccharide by van de Wiel, P A, Witvliet, M H, Evenberg, D, Derks, H J, Beuvery, E C

“…A semi-synthetic vaccine against Pseudomonas aeruginosa immunotype 3 was prepared by chemical coupling of P. aeruginosa immunotype 3 O-polysaccharide to…”
Get more information