Search Results - "van de Waterbeemd, Michiel"

Complete and cooperative in vitro assembly of computationally designed self-assembling protein nanomaterials by Wargacki, Adam J., Wörner, Tobias P., van de Waterbeemd, Michiel, Ellis, Daniel, Heck, Albert J. R., King, Neil P.

“…Recent advances in computational methods have enabled the predictive design of self-assembling protein nanomaterials with atomic-level accuracy. These design…”
Get full text

Molecular Basis of Transcription-Coupled Pre-mRNA Capping by Martinez-Rucobo, Fuensanta W., Kohler, Rebecca, van de Waterbeemd, Michiel, Heck, Albert J.R., Hemann, Matthias, Herzog, Franz, Stark, Holger, Cramer, Patrick

“…Capping is the first step in pre-mRNA processing, and the resulting 5′-RNA cap is required for mRNA splicing, export, translation, and stability. Capping is…”
Get full text

The diverse and expanding role of mass spectrometry in structural and molecular biology by Lössl, Philip, van de Waterbeemd, Michiel, Heck, Albert JR

“…The emergence of proteomics has led to major technological advances in mass spectrometry (MS). These advancements not only benefitted MS‐based high‐throughput…”
Get full text

Structure and assembly of scalable porous protein cages by Sasaki, Eita, Böhringer, Daniel, van de Waterbeemd, Michiel, Leibundgut, Marc, Zschoche, Reinhard, Heck, Albert J. R., Ban, Nenad, Hilvert, Donald

“…Proteins that self-assemble into regular shell-like polyhedra are useful, both in nature and in the laboratory, as molecular containers. Here we describe…”
Get full text

Dissecting ribosomal particles throughout the kingdoms of life using advanced hybrid mass spectrometry methods by van de Waterbeemd, Michiel, Tamara, Sem, Fort, Kyle L., Damoc, Eugen, Franc, Vojtech, Bieri, Philipp, Itten, Martin, Makarov, Alexander, Ban, Nenad, Heck, Albert J. R.

“…Biomolecular mass spectrometry has matured strongly over the past decades and has now reached a stage where it can provide deep insights into the structure and…”
Get full text

Stochastic palmitoylation of accessible cysteines in membrane proteins revealed by native mass spectrometry by Rodenburg, Remco N. P., Snijder, Joost, van de Waterbeemd, Michiel, Schouten, Arie, Granneman, Joke, Heck, Albert J. R., Gros, Piet

“…Palmitoylation affects membrane partitioning, trafficking and activities of membrane proteins. However, how specificity of palmitoylation and multiple…”
Get full text

Structural Analysis of a Temperature-Induced Transition in a Viral Capsid Probed by HDX-MS by van de Waterbeemd, Michiel, Llauró, Aida, Snijder, Joost, Valbuena, Alejandro, Rodríguez-Huete, Alicia, Fuertes, Miguel Angel, de Pablo, Pedro. J., Mateu, Mauricio G., Heck, Albert J.R.

“…Icosahedral viral capsids are made of a large number of symmetrically organized protein subunits whose local movements can be essential for infection. In the…”
Get full text

Simultaneous Assessment of Kinetic, Site-Specific, and Structural Aspects of Enzymatic Protein Phosphorylation by van de Waterbeemd, Michiel, Lössl, Philip, Gautier, Violette, Marino, Fabio, Yamashita, Masami, Conti, Elena, Scholten, Arjen, Heck, Albert J. R.

“…Protein phosphorylation is a widespread process forming the mechanistic basis of cellular signaling. Up to now, different aspects, for example,…”
Get full text

Structural analysis of calmodulin binding to ion channels demonstrates the role of its plasticity in regulation by Kovalevskaya, Nadezda V., van de Waterbeemd, Michiel, Bokhovchuk, Fedir M., Bate, Neil, Bindels, René J. M., Hoenderop, Joost G. J., Vuister, Geerten W.

“…The Ca 2+ -binding protein calmodulin (CaM) is a well-known regulator of ion-channel activity. Consequently, the Protein Data Bank contains many structures of…”
Get full text

High-fidelity mass analysis unveils heterogeneity in intact ribosomal particles by van de Waterbeemd, Michiel, Fort, Kyle L, Boll, Dmitriy, Reinhardt-Szyba, Maria, Routh, Andrew, Makarov, Alexander, Heck, Albert J R

“…Instrumental modifications enable native mass spectrometry analysis with unprecedented mass resolution, especially at high mass-to-charge ratios, as…”
Get full text

Defining the Stoichiometry and Cargo Load of Viral and Bacterial Nanoparticles by Orbitrap Mass Spectrometry by Snijder, Joost, van de Waterbeemd, Michiel, Damoc, Eugen, Denisov, Eduard, Grinfeld, Dmitry, Bennett, Antonette, Agbandje-McKenna, Mavis, Makarov, Alexander, Heck, Albert J. R

“…Accurate mass analysis can provide useful information on the stoichiometry and composition of protein-based particles, such as virus-like assemblies. For…”
Get full text

Examining the Heterogeneous Genome Content of Multipartite Viruses BMV and CCMV by Native Mass Spectrometry by van de Waterbeemd, Michiel, Snijder, Joost, Tsvetkova, Irina B., Dragnea, Bogdan G., Cornelissen, Jeroen J., Heck, Albert J. R.

“…Since the concept was first introduced by Brian Chait and co-workers in 1991, mass spectrometry of proteins and protein complexes under non-denaturing…”
Get full text

Site‐specific functionality and tryptophan mimicry of lipidation in tetraspanin CD9 by Neviani, Viviana, Deventer, Sjoerd, Wörner, Tobias P., Xenaki, Katerina T., Waterbeemd, Michiel, Rodenburg, Remco N. P., Wortel, Inge M. N., Kuiper, Jeroen K., Huisman, Sofie, Granneman, Joke, Bergen en Henegouwen, Paul M. P., Heck, Albert J. R., Spriel, Annemiek B., Gros, Piet

“…Lipidation of transmembrane proteins regulates many cellular activities, including signal transduction, cell–cell communication, and membrane trafficking…”
Get full text

Conformational landscape and pathway of disulfide bond reduction of human alpha defensin by Snijder, Joost, van de Waterbeemd, Michiel, Glover, Matthew S., Shi, Liuqing, Clemmer, David E., Heck, Albert J. R.

“…Human alpha defensins are a class of antimicrobial peptides with additional antiviral activity. Such antimicrobial peptides constitute a major part of…”
Get full text

Back Cover: Simultaneous Assessment of Kinetic, Site-Specific, and Structural Aspects of Enzymatic Protein Phosphorylation (Angew. Chem. Int. Ed. 36/2014) by van de Waterbeemd, Michiel, Lössl, Philip, Gautier, Violette, Marino, Fabio, Yamashita, Masami, Conti, Elena, Scholten, Arjen, Heck, Albert J. R.

Get full text

Simultane Untersuchung kinetischer, ortsspezifischer und struktureller Aspekte enzymatischer Proteinphosphorylierungen by van de Waterbeemd, Michiel, Lössl, Philip, Gautier, Violette, Marino, Fabio, Yamashita, Masami, Conti, Elena, Scholten, Arjen, Heck, Albert J. R.

“…Die Phosphorylierung von Proteinen ist ein weit verbreiteter Prozess, welcher die mechanistische Grundlage für zelluläre Signalübertragung bildet. Derzeit…”
Get full text

Rücktitelbild: Simultane Untersuchung kinetischer, ortsspezifischer und struktureller Aspekte enzymatischer Proteinphosphorylierungen (Angew. Chem. 36/2014) by van de Waterbeemd, Michiel, Lössl, Philip, Gautier, Violette, Marino, Fabio, Yamashita, Masami, Conti, Elena, Scholten, Arjen, Heck, Albert J. R.

Get full text

Simultane Untersuchung kinetischer, ortsspezifischer und struktureller Aspekte enzymatischer Proteinphosphorylierungen by van de Waterbeemd, Michiel, Lössl, Philip, Gautier, Violette, Marino, Fabio, Yamashita, Masami, Conti, Elena, Scholten, Arjen, Heck, Albert J. R.

“…Abstract Die Phosphorylierung von Proteinen ist ein weit verbreiteter Prozess, welcher die mechanistische Grundlage für zelluläre Signalübertragung bildet…”
Get full text