Search Results - "van de Logt, Erik"

Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions by Rotheneder, Matthias, Stakyte, Kristina, van de Logt, Erik, Bartho, Joseph D., Lammens, Katja, Fan, Yilan, Alt, Aaron, Kessler, Brigitte, Jung, Christophe, Roos, Wynand P., Steigenberger, Barbara, Hopfner, Karl-Peter

“…The DNA double-strand break repair complex Mre11-Rad50-Nbs1 (MRN) detects and nucleolytically processes DNA ends, activates the ATM kinase, and tethers DNA at…”
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Structural mechanism of endonucleolytic processing of blocked DNA ends and hairpins by Mre11-Rad50 by Gut, Fabian, Käshammer, Lisa, Lammens, Katja, Bartho, Joseph D., Boggusch, Anna-Maria, van de Logt, Erik, Kessler, Brigitte, Hopfner, Karl-Peter

“…DNA double-strand breaks (DSBs) threaten genome stability and are linked to tumorigenesis in humans. Repair of DSBs requires the removal of attached proteins…”
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Proteasomal degradation induced by DPP9‐mediated processing competes with mitochondrial protein import by Finger, Yannik, Habich, Markus, Gerlich, Sarah, Urbanczyk, Sophia, van de Logt, Erik, Koch, Julian, Schu, Laura, Lapacz, Kim Jasmin, Ali, Muna, Petrungaro, Carmelina, Salscheider, Silja Lucia, Pichlo, Christian, Baumann, Ulrich, Mielenz, Dirk, Dengjel, Joern, Brachvogel, Bent, Hofmann, Kay, Riemer, Jan

“…Plasticity of the proteome is critical to adapt to varying conditions. Control of mitochondrial protein import contributes to this plasticity. Here, we…”
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The Stress-Dependent Dynamics of Saccharomyces cerevisiae tRNA and rRNA Modification Profiles by Yoluç, Yasemin, van de Logt, Erik, Kellner-Kaiser, Stefanie

“…RNAs are key players in the cell, and to fulfil their functions, they are enzymatically modified. These modifications have been found to be dynamic and…”
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The rRNA m 6 A methyltransferase METTL5 is involved in pluripotency and developmental programs by Ignatova, Valentina V, Stolz, Paul, Kaiser, Steffen, Gustafsson, Tobias H, Lastres, Palma Rico, Sanz-Moreno, Adrián, Cho, Yi-Li, Amarie, Oana V, Aguilar-Pimentel, Antonio, Klein-Rodewald, Tanja, Calzada-Wack, Julia, Becker, Lore, Marschall, Susan, Kraiger, Markus, Garrett, Lillian, Seisenberger, Claudia, Hölter, Sabine M, Borland, Kayla, Van De Logt, Erik, Jansen, Pascal W T C, Baltissen, Marijke P, Valenta, Magdalena, Vermeulen, Michiel, Wurst, Wolfgang, Gailus-Durner, Valerie, Fuchs, Helmut, Hrabe de Angelis, Martin, Rando, Oliver J, Kellner, Stefanie M, Bultmann, Sebastian, Schneider, Robert

“…Covalent chemical modifications of cellular RNAs directly impact all biological processes. However, our mechanistic understanding of the enzymes catalyzing…”
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The rRNA m6A methyltransferase METTL5 is involved in pluripotency and developmental programs by Ignatova, Valentina V, Stolz, Paul, Kaiser, Steffen, Gustafsson, Tobias H, Lastres, Palma Rico, Sanz-Moreno, Adrián, Cho, Yi-Li, Amarie, Oana V, Aguilar-Pimentel, Antonio, Klein-Rodewald, Tanja, Calzada-Wack, Julia, Becker, Lore, Marschall, Susan, Kraiger, Markus, Garrett, Lillian, Seisenberger, Claudia, Hölter, Sabine M, Borland, Kayla, Van De Logt, Erik, Jansen, Pascal W T C, Baltissen, Marijke P, Valenta, Magdalena, Vermeulen, Michiel, Wurst, Wolfgang, Gailus-Durner, Valerie, Fuchs, Helmut, Hrabe de Angelis, Martin, Rando, Oliver J, Kellner, Stefanie M, Bultmann, Sebastian, Schneider, Robert

“…In this study, Ignatova et al. performed a systematic screen to uncover new RNA methyltransferases, and demonstrate that the methyltransferase-like 5 (METTL5)…”
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