Search Results - "van de Geer, Ellen"

Elevated enhancer-oncogene contacts and higher oncogene expression levels by recurrent CTCF inactivating mutations in acute T cell leukemia by Smits, Willem K., Vermeulen, Carlo, Hagelaar, Rico, Kimura, Shunsuke, Vroegindeweij, Eric M., Buijs-Gladdines, Jessica G.C.A.M., van de Geer, Ellen, Verstegen, Marjon J.A.M., Splinter, Erik, van Reijmersdal, Simon V., Buijs, Arjan, Galjart, Niels, van Eyndhoven, Winfried, van Min, Max, Kuiper, Roland, Kemmeren, Patrick, Mullighan, Charles G., de Laat, Wouter, Meijerink, Jules P.P.

“…Monoallelic inactivation of CCCTC-binding factor (CTCF) in human cancer drives altered methylated genomic states, altered CTCF occupancy at promoter and…”
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Kaposiform hemangioendothelioma and tufted angioma – (epi)genetic analysis including genome-wide methylation profiling by Ten Broek, Roel W., Koelsche, Christian, Eijkelenboom, Astrid, Mentzel, Thomas, Creytens, David, Vokuhl, Christian, van Gorp, Joost M., Versleijen-Jonkers, Yvonne M., van der Vleuten, Carine J., Kemmeren, Patrick, van de Geer, Ellen, von Deimling, Andreas, Flucke, Uta

“…Kaposiform hemangioendothelioma (KHE) is a locally aggressive vascular condition of childhood and is clinicopathologically related to tufted angioma (TA), a…”
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Trecode: A FAIR Eco-System for the Analysis and Archiving of Omics Data in a Combined Diagnostic and Research Setting by Kerstens, Hindrik HD, Hehir-Kwa, Jayne Y, van de Geer, Ellen, van Run, Chris, Badloe, Shashi, Janse, Alex, Baker-Hernandez, John, de Vos, Sam, van der Leest, Douwe, Verwiel, Eugène TP, Tops, Bastiaan BJ, Kemmeren, Patrick

“…The increase in speed, reliability, and cost-effectiveness of high-throughput sequencing has led to the widespread clinical application of genome (WGS), exome…”
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DNA Methylation Profiling Identifies Distinct Clusters in Angiosarcomas by Weidema, Marije E, van de Geer, Ellen, Koelsche, Christian, Desar, Ingrid M E, Kemmeren, Patrick, Hillebrandt-Roeffen, Melissa H S, Ho, Vincent K Y, van der Graaf, Winette T A, Versleijen-Jonkers, Yvonne M H, von Deimling, Andreas, Flucke, Uta E

“…DNA methylation profiling has previously uncovered biologically and clinically meaningful subgroups within many tumor types, but was not yet performed in…”
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Elevated Enhancer-Oncogene Contacts and Higher Oncogene Expression Levels By Recurrent CTCF inactivating Mutations in T Cell Acute Lymphoblastic Leukemia by Smits, Willem K., Vermeulen, Carlo, Hagelaar, Rico, Kimura, Shunsuke, Vroegindeweij, Eric, Buijs-Gladdines, Jessica G.C.A.M., Van De Geer, Ellen, Verstegen, Marjon J.A.M., Splinter, Erik, van Reijmersdal, Simon V., Buijs, Arjan, Galjart, Niels, Van Eyndhoven, Winfried, Van Min, Max Jan, Kuiper, Roland P, Kemmeren, Patrick, Mullighan, Charles G., De Laat, Wouter, Meijerink, Jules P.P.

“…Introduction. The CCCTC-binding factor (CTCF) regulates the 3D chromatin architecture by facilitating chromosomal loops and forming the boundaries of…”
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Guidelines for cell-type heterogeneity quantification based on a comparative analysis of reference-free DNA methylation deconvolution software by Decamps, Clémentine, Privé, Florian, Bacher, Raphael, Jost, Daniel, Waguet, Arthur, Houseman, Eugene Andres, Lurie, Eugene, Lutsik, Pavlo, Milosavljevic, Aleksandar, Scherer, Michael, Blum, Michael G B, Richard, Magali

“…Cell-type heterogeneity of tumors is a key factor in tumor progression and response to chemotherapy. Tumor cell-type heterogeneity, defined as the proportion…”
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Improved Gene Fusion Detection in Childhood Cancer Diagnostics Using RNA Sequencing by Hehir-Kwa, Jayne Y, Koudijs, Marco J, Verwiel, Eugene T P, Kester, Lennart A, van Tuil, Marc, Strengman, Eric, Buijs, Arjan, Kranendonk, Mariëtte E G, Hiemcke-Jiwa, Laura S, de Haas, Valerie, van de Geer, Ellen, de Leng, Wendy, van der Lugt, Jasper, Lijnzaad, Philip, Holstege, Frank C P, Kemmeren, Patrick, Tops, Bastiaan B J

“…Gene fusions play a significant role in cancer etiology, making their detection crucial for accurate diagnosis, prognosis, and determining therapeutic targets…”
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