Search Results - "van Zwieten, PA"

The direct effects of thyroid hormones on rat mesenteric resistance arteries by Zwaveling, J., Pfaffendorf, M., van Zwieten, PA

“…Summary— The direct relaxant effects of thyroid hormones on mesenteric resistance vessels were investigated using an isometric wire myograph. Both the L‐ and…”
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Antioxidant Activity of Nebivolol in the Rat Aorta by de Groot, Annemieke A, Mathy, Marie-Jeanne, van Zwieten, Pieter A, Peters, Stephan L. M

“…The β-blocker nebivolol is a racemic mixture of d- and l- enantiomers that displays negative inotropic as well as direct vasorelaxant activity. In addition, it…”
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Hydrogen sulphide: not only foul smelling, but also pathophysiologically relevant by van Zwieten, Pieter A

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Significant food interactions observed with a nifedipine modified-release formulation marketed in the European Union by Wonnemann, M, Schug, B, Schmücker, K, Brendel, E, van Zwieten, P A, Blume, H

“…The objective of this study was to compare the rate and extent of nifedipine bioavailability after single dose administration of Adalat OROS 30 (Reference) and…”
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The renaissance of centrally acting antihypertensive drugs by van Zwieten, P A

“…Classic centrally acting antihypertensive drugs such as clonidine, guanfacine and alpha-methyl-dioxyphenylalanine (alpha-methyl-DOPA) (via its active…”
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Inhibition of facilitation of sympathetic neurotransmission and angiotensin II-induced pressor effects in the pithed rat: comparison between valsartan, candesartan, eprosartan and embusartan by Balt, Jippe C, Mathy, Marie-Jeanne, Pfaffendorf, Martin, van Zwieten, Pieter A

“…BACKGROUND In the pithed rat model, endogenously generated angiotensin (Ang) II can enhance sympathetic neurotransmission by acting on Ang II type 1 (AT1)…”
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The influence of antihypertensive drug treatment on the prevention and regression of left ventricular hypertrophy by VAN ZWIETEN, P. A

“…Left ventricular hypertrophy (LVH) has been recognized as an important cardiovascular risk factor. Hypertensive disease is the most frequent background of LVH…”
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Effects of hypochlorite and hydrogen peroxide on cardiac autonomic receptors and vascular endothelial function by Sand, Carsten, Peters, Stephan LM, Pfaffendorf, Martin, Van Zwieten, Pieter A

“…Summary 1. Reactive oxygen species (ROS) are known to be involved in the progression of various cardiovascular diseases. One source of ROS is activated…”
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The influence of endogenously generated reactive oxygen species on the inotropic and chronotropic effects of adrenoceptor and ET-receptor stimulation by Sand, Carsten, Peters, Stephan L M, Pfaffendorf, Martin, van Zwieten, Pieter A

“…Reactive oxygen species (ROS) play a role in cardiovascular diseases such as heart failure and hypertension. Furthermore, increasing evidence has accumulated…”
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Drug treatment of isolated systolic hypertension by VAN ZWIETEN, Peter A

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Inhibition of angiotensin II-induced facilitation of sympathetic neurotransmission in the pithed rat: a comparison between losartan, irbesartan, telmisartan and captopril by Balt, Jippe C, Mathy, Marie-Jeanne, Pfaffendorf, Martin, van Zwieten, Pieter A

“…OBJECTIVENumerous studies have shown that angiotensin II enhances sympathetic nervous transmission. The objective of the present study was to quantify the…”
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Alpha‐adrenergic receptors in human blood vessels by Brummelen, P, Jie, K, Zwieten, PA

“…The evidence for the presence of postjunctional alpha 1‐ and alpha 2‐ adrenoceptor subtypes in human blood vessels is reviewed. Experiments in healthy subjects…”
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Nebivolol and endothelium dysfunction in salt-sensitive Dahl rats by van Zwieten, Pieter A

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The evaluation of the N-type channel blocking properties of cilnidipine and other voltage-dependent calcium antagonists by Nap, Alexander, Mathy, Marie-Jeanne, Balt, Jippe C., Pfaffendorf, Martin, Van Zwieten, Pieter A.

“…Sympathetic neurotransmission in tissues with intact sympathetic nerve arborization is extensively dependent on calcium influx via N‐type calcium‐channels. It…”
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Involvement of Reactive Oxygen Species in Angiotensin II-Induced Vasoconstriction by de Groot, Annemieke A, van Zwieten, Pieter A, Peters, Stephan L. M

“…In recent years it has been shown that angiotensin II (Ang II) stimulates formation of reactive oxygen species (ROS), presumably by activation of NAD(P)H…”
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Effects of calcitonin gene-related peptide and BIBN4096BS on myocardial ischemia in anesthetized rats by Wu, D M, van Zwieten, P A, Doods, H N

“…The cardioprotective effect of calcitonin gene-related peptide (CGRP) was investigated in an ischemia rat model. Ischemia-reperfusion injury was provoked by 60…”
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Endothelium-Dependent, Vasopressin-Induced Contractions in Rabbit Renal Arteries by Streefkerk, Jörn O, Pfaffendorf, Martin, van Zwieten, Pieter A

“…OBJECTIVESTo identify and quantify the stimulatory and inhibitory activity of endothelial factors on Arginine vasopressin (AVP)-induced contractions. METHODSIn…”
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Vasopressin-induced presynaptic facilitation of sympathetic neurotransmission in the pithed rat by Streefkerk, Jörn O, Mathy, Marie-Jeanne, Pfaffendorf, Martin, van Zwieten, Pieter A

“…OBJECTIVE Several studies have shown that arginine vasopressin (AVP) potentiates the sympathetic nervous transmission in isolated vessels. The present study…”
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The differential time courses of the vasodilator effects of various 1,4-dihydropyridines in isolated human small arteries are correlated to their lipophilicity by VAN DER LEE, Robin, PFAFFENDORF, Martin, VAN ZWIETEN, Pieter A

“…To investigate a possible relationship between the time courses of action of various calcium antagonists and their lipophilicity, characterized as log…”
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Pharmacology of centrally acting hypotensive drugs by van, Zwieten PA

“…1. A survey is given of the various aspects of centrally acting hypotensive drugs. The majority of centrally acting hypotensive agents act by way of central…”
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