Search Results - "van Wyk, Hester C"
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The Glasgow Microenvironment Score associates with prognosis and adjuvant chemotherapy response in colorectal cancer
Published in British journal of cancer (16-02-2021)“…Background The Glasgow Microenvironment Score (GMS) combines peritumoural inflammation and tumour stroma percentage to assess interactions between tumour and…”
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The Relationship Between Tumor Budding, Tumor Microenvironment, and Survival in Patients with Primary Operable Colorectal Cancer
Published in Annals of surgical oncology (01-12-2019)“…Background Tumor budding is an independent prognostic factor in colorectal cancer (CRC) and has recently been well-defined by the International Tumour Budding…”
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The relationship between tumour budding, the tumour microenvironment and survival in patients with primary operable colorectal cancer
Published in British journal of cancer (12-07-2016)“…Background: Tumour budding has been reported to reflect invasiveness, metastasis and unfavourable prognosis in colorectal cancer. The aim of the study was to…”
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Systematic review of tumour budding and association with common mutations in patients with colorectal cancer
Published in Critical reviews in oncology/hematology (01-11-2021)“…[Display omitted] •Meta-analysis evaluated relationship between mutated KRAS/BRAF or MSI tumour and tumour budding in colorectal cancer patients.•17 potential…”
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Spatially Resolved Transcriptomics Deconvolutes Prognostic Histological Subgroups in Patients with Colorectal Cancer and Synchronous Liver Metastases
Published in Cancer research (Chicago, Ill.) (14-04-2023)“…Strong immune responses in primary colorectal cancer correspond with better patient survival following surgery compared with tumors with predominantly stromal…”
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The relationship between the Glasgow Microenvironment Score and Markers of Epithelial-to-Mesenchymal Transition in TNM II-III Colorectal Cancer
Published in Human pathology (01-09-2022)“…Recently published work on the Glasgow Microenvironment Score (GMS) demonstrated its relevance as a biomarker in TNM II-III colorectal cancer (CRC)…”
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The detection and role of lymphatic and blood vessel invasion in predicting survival in patients with node negative operable primary colorectal cancer
Published in Critical reviews in oncology/hematology (01-04-2014)“…Abstract Although vascular invasion in colorectal cancer has been recognised since 1938, detection methods and results remain inconsistent. Vascular invasion…”
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Protein expression of S100A2 reveals it association with patient prognosis and immune infiltration profile in colorectal cancer
Published in Journal of Cancer (01-01-2023)“…Colorectal cancer (CRC) is the third most diagnosed cancer worldwide. Despite a well-established knowledge of tumour development, biomarkers to predict patient…”
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Relationship between tumour PTEN/Akt/COX-2 expression, inflammatory response and survival in patients with colorectal cancer
Published in Oncotarget (25-10-2016)“…In patients with colorectal cancer (CRC), local and systemic inflammatory responses have been extensively reported to associate with cancer survival. However,…”
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CXCL8 expression is associated with advanced stage, right sidedness, and distinct histological features of colorectal cancer
Published in The journal of pathology. Clinical research (01-11-2022)“…CXCL8 is an inflammatory chemokine elevated in the colorectal cancer (CRC) tumour microenvironment. CXCR2, the major receptor for CXCL8, is predominantly…”
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An investigation into the relationships between tumour invasiveness, the tumour micro-environment and survival in patients with primary operable colorectal cancer
Published 01-01-2017“…Colorectal cancer is the second commonest cause of cancer-related death after lung cancer. Prognostic features of colorectal cancer are important in…”
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