Search Results - "van Willigen, G."

Antibody responses against SARS-CoV-2 variants induced by four different SARS-CoV-2 vaccines in health care workers in the Netherlands: A prospective cohort study by van Gils, Marit J, Lavell, Ayesha, van der Straten, Karlijn, Appelman, Brent, Bontjer, Ilja, Poniman, Meliawati, Burger, Judith A, Oomen, Melissa, Bouhuijs, Joey H, van Vught, Lonneke A, Slim, Marleen A, Schinkel, Michiel, Wynberg, Elke, van Willigen, Hugo D G, Grobben, Marloes, Tejjani, Khadija, van Rijswijk, Jacqueline, Snitselaar, Jonne L, Caniels, Tom G, Vlaar, Alexander P J, Prins, Maria, de Jong, Menno D, de Bree, Godelieve J, Sikkens, Jonne J, Bomers, Marije K, Sanders, Rogier W

“…Emerging and future SARS-CoV-2 variants may jeopardize the effectiveness of vaccination campaigns. Therefore, it is important to know how the different…”
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Inflammatory profiles are associated with long COVID up to 6 months after COVID-19 onset: A prospective cohort study of individuals with mild to critical COVID-19 by Wynberg, Elke, Han, Alvin X, van Willigen, Hugo D G, Verveen, Anouk, van Pul, Lisa, Maurer, Irma, van Leeuwen, Ester M, van den Aardweg, Joost G, de Jong, Menno D, Nieuwkerk, Pythia, Prins, Maria, Kootstra, Neeltje A, de Bree, Godelieve J

“…After initial COVID-19, immune dysregulation may persist and drive post-acute sequelae of COVID-19 (PASC). We described longitudinal trajectories of cytokines…”
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One-fourth of COVID-19 patients have an impaired pulmonary function after 12 months of disease onset by van Willigen, Hugo D. G, Wynberg, Elke, Verveen, Anouk, Dijkstra, Maartje, Verkaik, Bas J, Figaroa, Orlane J. A, de Jong, Marianne C, van der Veen, Annelou L. I. P, Makowska, Agata, Koedoot, Nelleke, Nieuwkerk, Pythia T, Boyd, Anders, Prins, Maria, de Jong, Menno D, de Bree, Godelieve J, van den Aardweg, Joost G

“…Background There is increasing data that show a persistently impaired pulmonary function upon recovery after severe infection. Little is known however about…”
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Determinants of epidemic size and the impacts of lulls in seasonal influenza virus circulation by de Jong, Simon P. J., Felix Garza, Zandra C., Gibson, Joseph C., van Leeuwen, Sarah, de Vries, Robert P., Boons, Geert-Jan, van Hoesel, Marliek, de Haan, Karen, van Groeningen, Laura E., Hulme, Katina D., van Willigen, Hugo D. G., Wynberg, Elke, de Bree, Godelieve J., Matser, Amy, Bakker, Margreet, van der Hoek, Lia, Prins, Maria, Kootstra, Neeltje A., Eggink, Dirk, Nichols, Brooke E., Han, Alvin X., de Jong, Menno D., Russell, Colin A.

“…During the COVID-19 pandemic, levels of seasonal influenza virus circulation were unprecedentedly low, leading to concerns that a lack of exposure to influenza…”
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Non-invasive fetal electrocardiography, electrohysterography and speckle-tracking echocardiography in the second trimester: study protocol of a longitudinal prospective cohort study (BEATS-study) by Nichting, T. J., Frenken, M. W. E., van der Woude, D. A. A., van Oostrum, N. H. M., de Vet, C. M., van Willigen, B. G., van Laar, J. O. E. H., van der Ven, M., Oei, S. G.

“…Abstract Background Worldwide, hypertensive disorders of pregnancy (HDP), fetal growth restriction (FGR) and preterm birth remain the leading causes of…”
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The effect of SARS-CoV-2 vaccination on post-acute sequelae of COVID-19 (PASC): A prospective cohort study by Wynberg, Elke, Han, Alvin X., Boyd, Anders, van Willigen, Hugo D.G., Verveen, Anouk, Lebbink, Romy, van der Straten, Karlijn, Kootstra, Neeltje, van Gils, Marit J., Russell, Colin, Leenstra, Tjalling, de Jong, Menno D., de Bree, Godelieve J., Prins, Maria

“…•Vaccination did not reduce symptoms of post-acute sequelae (PASC).•Antibody kinetics did not differ between participants with and without PASC.•Early antibody…”
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A review study of fetal circulatory models to develop a digital twin of a fetus in a perinatal life support system by van Willigen, Bettine G., van der Hout-van der Jagt, M. Beatrijs, Huberts, Wouter, van de Vosse, Frans N.

“…Background Preterm birth is the main cause of neonatal deaths with increasing mortality and morbidity rates with decreasing GA at time of birth. Currently,…”
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A Multiscale Mathematical Model for the Fetal Blood Circulation of the Second Half of Pregnancy by van Willigen, Bettine G, van der Hout-van der Jagt, M Beatrijs, Bovendeerd, Peter H M, Huberts, Wouter, van de Vosse, Frans N

“…Doppler ultrasound is a commonly used method to assess hemodynamics of the fetal cardiovascular system and to monitor the well-being of the fetus. Indices…”
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Aberrant neutrophil degranulation in hospitalized patients with COVID‐19 partially remains for 6 months by Hafkamp, Florianne M.J., Taanman‐Kueter, Esther W. M., Capel, Toni M. M., Wynberg, Elke, Willigen, Hugo D. G., Verveen, Anouk, Kootstra, Neeltje A., Nieuwkerk, Pythia, Jong, Menno D., Bree, Godelieve J., Prins, Maria, Hazenberg, Mette D., Groot Kormelink, Tom, Jong, Esther C.

“…Neutrophils are important players in COVID‐19, contributing to tissue damage by release of inflammatory mediators, including ROS and neutrophil elastase…”
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Increased glutamine synthetase but normal EAAT2 expression in platelets of ALS patients by Bos, I.W.M., Hoogland, G., Meine Jansen, C.F., Willigen, G. van, Spierenburg, H.A., van den Berg, L.H., de Graan, P.N.E.

“…Amyotrophic lateral sclerosis is a fatal neurodegenerative disease and glutamate excitotoxicity has been implicated in its pathogenesis. Platelets contain a…”
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Two-year trajectories of COVID-19 symptoms and their association with illness perception: A prospective cohort study in Amsterdam, the Netherlands by Wynberg, Elke, Verveen, Anouk, van Willigen, Hugo D G, Nieuwkerk, Pythia, Davidovich, Udi, Lok, Anja, de Jong, Menno D, de Bree, Godelieve J, Leenstra, Tjalling, Knoop, Hans, Prins, Maria, Boyd, Anders

“…We used data from a prospective cohort to explore 2-year trajectories of 'long COVID' (persistent symptoms after SARS-CoV-2 infection) and their association…”
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Occult blood flow patterns distal to an occluded artery in acute ischemic stroke by Arrarte Terreros, Nerea, van Willigen, Bettine G, Niekolaas, Wera S, Tolhuisen, Manon L, Brouwer, Josje, Coutinho, Jonathan M, Beenen, Ludo FM, Majoie, Charles BLM, van Bavel, Ed, Marquering, Henk A

“…Residual blood flow distal to an arterial occlusion in patients with acute ischemic stroke (AIS) is associated with favorable patient outcome. Both collateral…”
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Detection of postpartum uterine activity with electrohysterography by Thijssen, Kirsten M.J., van den Broek, Michelle J.M., Koenraads, Feikje A., Cantineau-Goedegebuure, Joyce I., Papatsonis, Dimitri N.M., van Willigen, Bettine G., Dieleman, Jeanne P., van der Hout-van der Jagt, M. Beatrijs, Westerhuis, Michelle E.M.H., Oei, S. Guid

“…•Currently there is no accurate method available for postpartum uterine monitoring.•Uterine atony causing postpartum hemorrhage is associated with maternal…”
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A predictive computational model to estimate myocardial temperature during intracoronary hypothermia in acute myocardial infarction by van Willigen, Bettine G., Otterspoor, Luuk C., van ’t Veer, Marcel, Rosalina, Tilaï T., Pijls, Nico H.J., van de Vosse, Frans N.

“…•Study of selective myocardial hypothermia is relevant, because it potentially reduces reperfusion injury due to percutaneous coronary intervention.•Verified…”
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Evolution of Coronavirus Disease 2019 (COVID-19) Symptoms During the First 12 Months After Illness Onset by Wynberg, Elke, van Willigen, Hugo D G, Dijkstra, Maartje, Boyd, Anders, Kootstra, Neeltje A, van den Aardweg, Joost G, van Gils, Marit J, Matser, Amy, de Wit, Marije R, Leenstra, Tjalling, de Bree, Godelieve, de Jong, Menno D, Prins, Maria

“…Abstract Background Few robust longitudinal data on long-term coronavirus disease 2019 (COVID-19) symptoms are available. We evaluated symptom onset, severity…”
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Antigenic cartography using sera from sequence-confirmed SARS-CoV-2 variants of concern infections reveals antigenic divergence of Omicron by van der Straten, Karlijn, Guerra, Denise, van Gils, Marit J., Bontjer, Ilja, Caniels, Tom G., van Willigen, Hugo D.G., Wynberg, Elke, Poniman, Meliawati, Burger, Judith A., Bouhuijs, Joey H., van Rijswijk, Jacqueline, Olijhoek, Wouter, Liesdek, Marinus H., Lavell, A.H. Ayesha, Appelman, Brent, Sikkens, Jonne J., Bomers, Marije K., Han, Alvin X., Nichols, Brooke E., Prins, Maria, Vennema, Harry, Reusken, Chantal, de Jong, Menno D., de Bree, Godelieve J., Russell, Colin A., Eggink, Dirk, Sanders, Rogier W.

“…Large-scale vaccination campaigns have prevented countless hospitalizations and deaths due to COVID-19. However, the emergence of SARS-CoV-2 variants that…”
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Thrombin-stimulated glutamate uptake in human platelets is predominantly mediated by the glial glutamate transporter EAAT2 by Hoogland, G., Bos, I.W.M., Kupper, F., van Willigen, G., Spierenburg, H.A., van Nieuwenhuizen, O., de Graan, P.N.E.

“…Glutamate toxicity has been implicated in the pathogenesis of various neurological diseases. Glial glutamate transporters play a key role in the regulation of…”
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Mental health up to 12 months following SARS-CoV-2 infection: A prospective cohort study by Verveen, Anouk, Wynberg, Elke, van Willigen, Hugo D G, Davidovich, Udi, Lok, Anja, Moll van Charante, Eric P, de Jong, Menno D, de Bree, Godelieve, Prins, Maria, Knoop, Hans, Nieuwkerk, Pythia T

“…To investigate to what extent individuals report clinically relevant levels of depression, anxiety, post-traumatic stress disorder (PTSD) symptoms and…”
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Targeting of porcine pancreatic phospholipase A2 to human platelets: introduction of an RGD sequence by genetic engineering by Bekkers, A C, van der Vuurst, H, van Willigen, G, Akkerman, J W, Verheij, H M

“…The possibility to induce specific disruption of activated platelets by binding of porcine pancreatic phospholipase A2 (PLA2) was tested by constructing a set…”
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Health-related quality of life among persons with initial mild, moderate, and severe or critical COVID-19 at 1 and 12 months after infection: a prospective cohort study by Verveen, Anouk, Wynberg, Elke, van Willigen, Hugo D. G, Davidovich, Udi, Lok, Anja, Moll van Charante, Eric P, de Jong, Menno D, de Bree, Godelieve, Prins, Maria, Knoop, Hans, Nieuwkerk, Pythia T, Agard, Ivette, Ayal, Jane, Cavdar, Floor, Craanen, Marianne, Deuring, Annemarieke, van Dijk, Annelies, Ersan, Ertan, del Grande, Laura, Hartman, Joost, Koedoot, Nelleke, Leenstra, Tjalling, Lebbink, Romy, Loomans, Dominique, Makowska, Agata, du Maine, Tom, de Man, Ilja, Matser, Amy, van der Meij, Lizenka, van Polanen, Marleen, Oud, Maria, Reid, Clark, Storey, Leeann, van Wijk, Marc, van den Aardweg, Joost, van Assem, Joyce, van Beek, Marijne, Blankert, Thyra, Dijkstra, Maartje, Figaroa, Orlane, Frenkel, Leah, van Gils, Marit, van Haga, Jelle, Han, Xiaochuan Alvin, Harskamp-Holwerda, Agnes, Hazenberg, Mette, Hidad, Soemeja, de Jong, Nina, Kootstra, Neeltje, Kuijt, Lara, Russell, Colin, van der Straten, Karlijn, van der Veen, Annelou, Verkaik, Bas, Visser, Gerben-Rienk

“…Abstract Background Currently, there is limited evidence about the long-term impact on physical, social and emotional functioning, i.e. health-related quality…”
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