Search Results - "van Wamel, A."

Increasing the Endothelial Layer Permeability Through Ultrasound-Activated Microbubbles by Kooiman $^{}$, Klazina, Emmer, Marcia, Foppen-Harteveld, Miranda, van Wamel, Annemieke, de Jong, Nico

“…Drug delivery to a diseased tissue will be more efficient if the vascular endothelial permeability is increased. Recent studies have shown that the…”
Get full text

Ultrasound microbubble induced endothelial cell permeability by van Wamel, A., Kooiman, K., Emmer, M., ten Cate, F.J., Versluis, M., de Jong, N.

Get full text

High-resolution ultrasonography of the cutaneous nerve branches in the hand and wrist by STOKVIS, A., VAN NECK, J. W., VAN DIJKE, C. F., VAN WAMEL, A., COERT, J. H.

“…Ultrasonography can be used in the diagnosis of various neuropathies, including nerve injury. Nerves often involved in traumatic and iatrogenic injury are…”
Get full text

The role of angiotensin II, endothelin-1 and transforming growth factor-beta as autocrine/paracrine mediators of stretch-induced cardiomyocyte hypertrophy by van Wamel, A J, Ruwhof, C, van der Valk-Kokshoom, L E, Schrier, P I, van der Laarse, A

“…Cardiac hypertrophy is a compensatory response of myocardial tissue upon increased mechanical load. Of the mechanical factors, stretch is rapidly followed by…”
Get full text

Direct, Autocrine and Paracrine Effects of Cyclic Stretch on Growth of Myocytes and Fibroblasts Isolated from Neonatal Rat Ventricles by Ruwhof, C., van Wamel, A.E.T., van der Valk, L.J.M., Schrier, P.I., van der Laarse, A.

“…Several studies have demonstrated that static stretch of cardiomyocytes induces cardiomyocyte hypertrophy. We investigated the effects of cyclic stretch, a…”
Get full text

Controlled drug delivery with ultrasound and gas microbubbles by van Wamel, A, Bouakaz, A, Bernard, B, ten Cate, F, de Jong, N

Get full text

Ultrasound and microbubble-targeted delivery of therapeutic compounds: ICIN Report Project 49: Drug and gene delivery through ultrasound and microbubbles by Juffermans, L. J. M., van Wamel, A., Henning, R. H., Kooiman, K., Emmer, M., de Jong, N., van Gilst, W. H., Musters, R., Paulus, W. J., van Rossum, A. C., Deelman, L. E., Kamp, O.

“…The molecular understanding of diseases has been accelerated in recent years, producing many new potential therapeutic targets. A noninvasive delivery system…”
Get full text

Microbubbles and ultrasound: from diagnosis to therapy by Dijkmans, P A, Juffermans, L J M, Musters, R J P, van Wamel, A, ten Cate, F J, van Gilst, W, Visser, C A, de Jong, N, Kamp, O

“…The development of ultrasound contrast agents, containing encapsulated microbubbles, has increased the possibilities for diagnostic imaging. Ultrasound…”
Get full text

Rapid Effects of Stretched Myocardial and Vascular Cells on Gene Expression of Neonatal Rat Cardiomyocytes with Emphasis on Autocrine and Paracrine Mechanisms by van Wamel, Annemieke J., Ruwhof, Cindy, van der Valk-Kokshoorn, Lizet J., Schrier, Peter I., van der Laarse, Arnoud

“…Passive stretch of the heart has a direct effect on cardiomyocytes and other cell types including cardiac fibroblasts, endothelial cells, and vascular smooth…”
Get full text

Staging and profiling of patients with dual disorders by Neven, A, van Wamel, A, van den Brink, W

“…Although there is a great need for staging and profiling in psychiatry, no-one has so far devised a staging and profiling model to aid diagnosis and treatment…”
Get more information

Ultrasound-induced encapsulated microbubble phenomena by Postema, Michiel, van Wamel, Annemieke, Lancée, Charles T, de Jong, Nico

“…When encapsulated microbubbles are subjected to high-amplitude ultrasound, the following phenomena have been reported: oscillation, translation, coalescence,…”
Get more information

Local drug and gene delivery through microbubbles and ultrasound by Juffermans, L J M, Dijkmans, P A, Musters, R J P, van Wamel, A, Bouakaz, A, Ten Cate, F J, Deelman, L, Visser, C A, de Jong, N, Kamp, O

“…Although gene therapy has great potential as a treatment for diseases, clinical trials are slowed down by the development of a safe and efficient gene delivery…”
Get full text

Oil-filled polymer microcapsules for ultrasound-mediated delivery of lipophilic drugs by Kooiman, Klazina, Böhmer, Marcel R., Emmer, Marcia, Vos, Hendrik J., Chlon, Ceciel, Shi, William T., Hall, Christopher S., de Winter, Suzanne H.P.M., Schroën, Karin, Versluis, Michel, de Jong, Nico, van Wamel, Annemieke

“…The use of ultrasound contrast agents as local drug delivery systems continues to grow. Current limitations are the amount of drug that can be incorporated as…”
Get full text

Micromanipulation of endothelial cells: ultrasound-microbubble-cell interaction by van Wamel, Annemieke, Bouakaz, Ayache, Versluis, Michel, de Jong, Nico

“…Ultrasound (US) in combination with contrast microbubbles has been shown to alter the permeability of cell membranes without affecting cell viability. This…”
Get more information

High-speed photography during ultrasound illustrates potential therapeutic applications of microbubbles by Postema, Michiel, van Wamel, Annemieke, ten Cate, Folkert J., de Jong, Nico

“…Ultrasound contrast agents consist of microscopically small encapsulated bubbles that oscillate upon insonification. To enhance diagnostic ultrasound imaging…”
Get full text

The structure of the Bracco Ophiolite complex (Ligurian Apennines, Italy); a change from Alpine to Apennine polarity by Hoogerduijn Strating, E. H, Van Wamel, W. A

“…The Bracco ophiolite complex, exposed in the area studied as the Bracco Subunit of the Melange Nappe, is tectonically intercalated between the underlying…”
Get full text

Ultrasound contrast agents pushing drug delivery: high speed optical observations by Van Wamel, Annemieke, Kooiman, Klazina, De Jong, Nico

“…Ultrasound-activated-microbubbles can cause transient non-lethal sonoporation of cells. Studies of influx of cell-membrane impermeable-dye, genetic materials,…”
Get full text

Radionuclide tumour therapy with ultrasound contrast microbubbles by van Wamel, Annemieke, Bouakaz, Ayache, Bernard, Bert, ten Cate, Folkert, de Jong, Nico

“…Radionuclides have shown to be effective in tumour therapy. However, the side effects determine the maximum deliverable dose. Recently, it has been…”
Get full text

Optical investigation of ultrasound induced encapsulated microbubble oscillations: threshold and hysteresis effects by Emmer, M., Borsboom, J., van Wamel, A., Versluis, M., de Jong, N.

Get full text

Ultrasound-triggered local release of lipophilic drugs from a novel polymeric ultrasound contrast agent by Kooiman, K., Böhmer, M.R., Emmer, M., Vos, H.J., Chlon, C., Foppen-Harteveld, M., Versluis, M., de Jong, N., van Wamel, A.

“…The advantage of ultrasound contrast agents (UCAs) as drug delivery systems is the ability to non-invasively control the local and triggered release of a drug…”
Get full text