Search Results - "van Vuuren, Cloete"
-
1
Necrotising migratory erythema leading to the diagnosis of a metastatic glucagonoma without diabetes
Published in JEMDSA : the journal of endocrinology, metabolism and diabetes of South Africa (01-12-2020)“…A case of necrotising migratory erythema (NME), which is one of the distinctive paraneoplastic skin manifestations associated with the glucagonoma syndrome, is…”
Get full text
Journal Article -
2
Mapping the drivers of within-host pathogen evolution using massive data sets
Published in Nature communications (09-07-2019)“…Differences among hosts, resulting from genetic variation in the immune system or heterogeneity in drug treatment, can impact within-host pathogen evolution…”
Get full text
Journal Article -
3
HIV Control through a Single Nucleotide on the HLA-B Locus
Published in Journal of Virology (01-11-2012)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article -
4
Southern African HIV Clinicians Society Guidance on the use of dolutegravir in first-line antiretroviral therapy
Published in Southern African journal of HIV medicine (2018)“…The Southern African HIV Clinicians Society would like to update all HIV-treating clinicians with regard to the use of dolutegravir in women of childbearing…”
Get full text
Journal Article -
5
Appropriate clinical use of darunavir 800 mg
Published in Southern African journal of HIV medicine (2018)“…Southern African HIV Clinicians Society adult antiretroviral therapy (ART) guidelines currently recommend ritonavir-boosted atazanavir (ATV/r) 300/100 mg as…”
Get full text
Journal Article -
6
Task shifting of antiretroviral treatment from doctors to primary-care nurses in South Africa (STRETCH): a pragmatic, parallel, cluster-randomised trial
Published in The Lancet (British edition) (08-09-2012)“…Summary Background Robust evidence of the effectiveness of task shifting of antiretroviral therapy (ART) from doctors to other health workers is scarce. We…”
Get full text
Journal Article -
7
Adult antiretroviral therapy guidelines 2017
Published in Southern African journal of HIV medicine (2017)“…These guidelines are intended as an update to those published in the Southern African Journal of HIV Medicine in 2014 and the update on when to initiate…”
Get full text
Journal Article -
8
Human Immunodeficiency Virus Infection Impairs Th1 and Th17 Mycobacterium tuberculosis–Specific T-Cell Responses
Published in The Journal of infectious diseases (05-05-2018)“…HIV infection is associated with a complex pattern of Mycobacterium tuberculosis–specific T-cell impairment. In South African participants, we report an…”
Get full text
Journal Article -
9
Convalescent plasma in the treatment of moderate to severe COVID-19 pneumonia: a randomized controlled trial (PROTECT-Patient Trial)
Published in Scientific reports (15-02-2022)“…There is a need for effective therapy for COVID-19 pneumonia. Convalescent plasma has antiviral activity and early observational studies suggested benefit in…”
Get full text
Journal Article -
10
Occult HIV-1 drug resistance to thymidine analogues following failure of first-line tenofovir combined with a cytosine analogue and nevirapine or efavirenz in sub Saharan Africa: a retrospective multi-centre cohort study
Published in The Lancet infectious diseases (01-03-2017)“…Summary Background HIV-1 drug resistance to older thymidine analogue nucleoside reverse transcriptase inhibitor drugs has been identified in sub-Saharan Africa…”
Get full text
Journal Article -
11
Maintenance of Functional CD57+ Cytolytic CD4+ T Cells in HIV+ Elite Controllers
Published in Frontiers in immunology (2019)“…Cytolytic CD4+ T cells play a prominent role in chronic viral infection. CD4+ CTLs clones specific for HIV-1 Nef and Gag are capable of killing HIV-1 infected…”
Get full text
Journal Article -
12
A comprehensive overview of pneumococcal vaccination recommendations for adults in South Africa, 2022
Published in Journal of thoracic disease (01-10-2022)“…Pneumococcal infections remain a common global cause of significant morbidity and mortality. The first recommendations for adult pneumococcal vaccination,…”
Get full text
Journal Article -
13
Southern African HIV Clinicians Society guidelines for antiretroviral therapy in adults: 2020 update
Published in Southern African journal of HIV medicine (16-09-2020)“…Abstract only…”
Get full text
Journal Article -
14
Progression to AIDS in South Africa is associated with both reverting and compensatory viral mutations
Published in PloS one (22-04-2011)“…We lack the understanding of why HIV-infected individuals in South Africa progress to AIDS. We hypothesised that in end-stage disease there is a shifting…”
Get full text
Journal Article -
15
Barriers that prevent adults living with HBV infection from participating in clinical research: experience from South Africa
Published in Journal of Virus Eradication (01-03-2023)“…High profile international goals have been set for the elimination of hepatitis B virus (HBV) infection as a public health threat by the year 2030. Developing…”
Get full text
Journal Article -
16
Co-operative additive effects between HLA alleles in control of HIV-1
Published in PloS one (19-10-2012)“…HLA class I genotype is a major determinant of the outcome of HIV infection, and the impact of certain alleles on HIV disease outcome is well studied. Recent…”
Get full text
Journal Article -
17
Streamlining tasks and roles to expand treatment and care for HIV: randomised controlled trial protocol
Published in Current controlled trials in cardiovascular medicine (23-04-2008)“…A major barrier to accessing free government-provided antiretroviral treatment (ART) in South Africa is the shortage of suitably skilled health professionals…”
Get full text
Journal Article -
18
Global epidemiology of drug resistance after failure of WHO recommended first-line regimens for adult HIV-1 infection: a multicentre retrospective cohort study
Published in The Lancet infectious diseases (01-05-2016)“…Summary Background Antiretroviral therapy (ART) is crucial for controlling HIV-1 infection through wide-scale treatment as prevention and pre-exposure…”
Get full text
Journal Article -
19
Validation of laboratory developed serology assays for detection of IgG antibody to severe acute respiratory syndrome coronavirus 2 in the South African population
Published in Journal of virological methods (01-09-2022)“…Serological assays for detection of IgG, IgM or IgA against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) play an important role in…”
Get full text
Journal Article -
20
Adalimumab Treatment of Life-Threatening Tuberculosis
Published in Clinical infectious diseases (15-05-2009)“…Most guidelines call for the discontinuation of treatment with tumor necrosis factor blockers in patients who develop tuberculosis. We report a case of…”
Get full text
Journal Article