Search Results - "van Uelft, Martina"

Systemic alterations in neutrophils and their precursors in early-stage chronic obstructive pulmonary disease by Kapellos, Theodore S., Baßler, Kevin, Fujii, Wataru, Nalkurthi, Christina, Schaar, Anna C., Bonaguro, Lorenzo, Pecht, Tal, Galvao, Izabela, Agrawal, Shobhit, Saglam, Adem, Dudkin, Erica, Frishberg, Amit, de Domenico, Elena, Horne, Arik, Donovan, Chantal, Kim, Richard Y., Gallego-Ortega, David, Gillett, Tessa E., Ansari, Meshal, Schulte-Schrepping, Jonas, Offermann, Nina, Antignano, Ignazio, Sivri, Burcu, Lu, Wenying, Eapen, Mathew S., van Uelft, Martina, Osei-Sarpong, Collins, van den Berge, Maarten, Donker, Hylke C., Groen, Harry J.M., Sohal, Sukhwinder S., Klein, Johanna, Schreiber, Tina, Feißt, Andreas, Yildirim, Ali Önder, Schiller, Herbert B., Nawijn, Martijn C., Becker, Matthias, Händler, Kristian, Beyer, Marc, Capasso, Melania, Ulas, Thomas, Hasenauer, Jan, Pizarro, Carmen, Theis, Fabian J., Hansbro, Philip M., Skowasch, Dirk, Schultze, Joachim L.

“…Systemic inflammation is established as part of late-stage severe lung disease, but molecular, functional, and phenotypic changes in peripheral immune cells in…”
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Chromatin accessibility profiling of targeted cell populations with laser capture microdissection coupled to ATAC-seq by Carraro, Caterina, Bonaguro, Lorenzo, Srinivasa, Rachana, van Uelft, Martina, Isakzai, Victoria, Schulte-Schrepping, Jonas, Gambhir, Prerna, Elmzzahi, Tarek, Montgomery, Jessica V., Hayer, Hannah, Li, Yuanfang, Theis, Heidi, Kraut, Michael, Mahbubani, Krishnaa T., Aschenbrenner, Anna C., König, Ireen, Fava, Eugenio, Fried, Hans-Ulrich, De Domenico, Elena, Beyer, Marc, Saglam, Adem, Schultze, Joachim L.

“…Spatially resolved omics technologies reveal context-dependent cellular regulatory networks in tissues of interest. Beyond transcriptome analysis, information…”
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Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients by Aschenbrenner, Anna C, Mouktaroudi, Maria, Krämer, Benjamin, Oestreich, Marie, Antonakos, Nikolaos, Nuesch-Germano, Melanie, Gkizeli, Konstantina, Bonaguro, Lorenzo, Reusch, Nico, Baßler, Kevin, Saridaki, Maria, Knoll, Rainer, Pecht, Tal, Kapellos, Theodore S, Doulou, Sarandia, Kröger, Charlotte, Herbert, Miriam, Holsten, Lisa, Horne, Arik, Gemünd, Ioanna D, Rovina, Nikoletta, Agrawal, Shobhit, Dahm, Kilian, van Uelft, Martina, Drews, Anna, Lenkeit, Lena, Bruse, Niklas, Gerretsen, Jelle, Gierlich, Jannik, Becker, Matthias, Händler, Kristian, Kraut, Michael, Theis, Heidi, Mengiste, Simachew, De Domenico, Elena, Schulte-Schrepping, Jonas, Seep, Lea, Raabe, Jan, Hoffmeister, Christoph, ToVinh, Michael, Keitel, Verena, Rieke, Gereon, Talevi, Valentina, Skowasch, Dirk, Aziz, N Ahmad, Pickkers, Peter, van de Veerdonk, Frank L, Netea, Mihai G, Schultze, Joachim L, Kox, Matthijs, Breteler, Monique M B, Nattermann, Jacob, Koutsoukou, Antonia, Giamarellos-Bourboulis, Evangelos J, Ulas, Thomas

“…The SARS-CoV-2 pandemic is currently leading to increasing numbers of COVID-19 patients all over the world. Clinical presentations range from asymptomatic,…”
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The life-saving benefit of dexamethasone in severe COVID-19 is linked to a reversal of monocyte dysregulation by Knoll, Rainer, Helbig, Elisa T, Dahm, Kilian, Bolaji, Olufemi, Hamm, Frederik, Dietrich, Oliver, van Uelft, Martina, Müller, Sophie, Bonaguro, Lorenzo, Schulte-Schrepping, Jonas, Petrov, Lev, Krämer, Benjamin, Kraut, Michael, Stubbemann, Paula, Thibeault, Charlotte, Brumhard, Sophia, Theis, Heidi, Hack, Gudrun, De Domenico, Elena, Nattermann, Jacob, Becker, Matthias, Beyer, Marc D, Hillus, David, Georg, Philipp, Loers, Constantin, Tiedemann, Janina, Tober-Lau, Pinkus, Lippert, Lena, Millet Pascual-Leone, Belén, Tacke, Frank, Rohde, Gernot, Suttorp, Norbert, Witzenrath, Martin, Saliba, Antoine-Emmanuel, Ulas, Thomas, Polansky, Julia K, Sawitzki, Birgit, Sander, Leif E, Schultze, Joachim L, Aschenbrenner, Anna C, Kurth, Florian

“…Dexamethasone is a life-saving treatment for severe COVID-19, yet its mechanism of action is unknown, and many patients deteriorate or die despite timely…”
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Inactivation of ceramide synthase 2 catalytic activity in mice affects transcription of genes involved in lipid metabolism and cell division by Bickert, Andreas, Kern, Paul, van Uelft, Martina, Herresthal, Stefanie, Ulas, Thomas, Gutbrod, Katharina, Breiden, Bernadette, Degen, Joachim, Sandhoff, Konrad, Schultze, Joachim L., Dörmann, Peter, Hartmann, Dieter, Bauer, Reinhard, Willecke, Klaus

“…The replacement of two consecutive histidine residues by alanine residues in the catalytic center of ceramide synthase 2 in a new transgenic mouse mutant…”
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Cell-type-specific expression pattern of ceramide synthase 2 protein in mouse tissues by Kremser, Christiane, Klemm, Anna-Lena, van Uelft, Martina, Imgrund, Silke, Ginkel, Christina, Hartmann, Dieter, Willecke, Klaus

“…Ceramide synthase 2 (CerS2) catalyzes the synthesis of dihydroceramides from dihydrosphingosine and very long fatty acyl (C22–C24)-CoAs. CerS2-deficient (gene…”
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TGF-β specifies T FH versus T H 17 cell fates in murine CD4 + T cells through c-Maf by Chang, Yinshui, Bach, Luisa, Hasiuk, Marko, Wen, Lifen, Elmzzahi, Tarek, Tsui, Carlson, Gutiérrez-Melo, Nicolás, Steffen, Teresa, Utzschneider, Daniel T, Raj, Timsse, Jost, Paul Jonas, Heink, Sylvia, Cheng, Jingyuan, Burton, Oliver T, Zeiträg, Julia, Alterauge, Dominik, Dahlström, Frank, Becker, Jennifer-Christin, Kastl, Melanie, Symeonidis, Konstantinos, van Uelft, Martina, Becker, Matthias, Reschke, Sarah, Krebs, Stefan, Blum, Helmut, Abdullah, Zeinab, Paeschke, Katrin, Ohnmacht, Caspar, Neumann, Christian, Liston, Adrian, Meissner, Felix, Korn, Thomas, Hasenauer, Jan, Heissmeyer, Vigo, Beyer, Marc, Kallies, Axel, Jeker, Lukas T, Baumjohann, Dirk

“…T follicular helper (T ) cells are essential for effective antibody responses, but deciphering the intrinsic wiring of mouse T cells has long been hampered by…”
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