Search Results - "van Turnhout, Mark C."

An automated real-time microfluidic platform to probe single NK cell heterogeneity and cytotoxicity on-chip by Subedi, Nikita, Van Eyndhoven, Laura C., Hokke, Ayla M., Houben, Lars, Van Turnhout, Mark C., Bouten, Carlijn V. C., Eyer, Klaus, Tel, Jurjen

“…Cytotoxicity is a vital effector mechanism used by immune cells to combat pathogens and cancer cells. While conventional cytotoxicity assays rely on averaged…”
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Colorful protein-based fluorescent probes for collagen imaging by Aper, Stijn J A, van Spreeuwel, Ariane C C, van Turnhout, Mark C, van der Linden, Ardjan J, Pieters, Pascal A, van der Zon, Nick L L, de la Rambelje, Sander L, Bouten, Carlijn V C, Merkx, Maarten

“…Real-time visualization of collagen is important in studies on tissue formation and remodeling in the research fields of developmental biology and tissue…”
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Notch signaling regulates strain-mediated phenotypic switching of vascular smooth muscle cells by Karakaya, Cansu, van Turnhout, Mark C., Visser, Valery L., Ristori, Tommaso, Bouten, Carlijn V. C., Sahlgren, Cecilia M., Loerakker, Sandra

“…Mechanical stimuli experienced by vascular smooth muscle cells (VSMCs) and mechanosensitive Notch signaling are important regulators of vascular growth and…”
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Cellular Contact Guidance Emerges from Gap Avoidance by Buskermolen, Antonetta B.C., Ristori, Tommaso, Mostert, Dylan, van Turnhout, Mark C., Shishvan, Siamak S., Loerakker, Sandra, Kurniawan, Nicholas A., Deshpande, Vikram S., Bouten, Carlijn V.C.

“…In the presence of anisotropic biochemical or topographical patterns, cells tend to align in the direction of these cues—a widely reported phenomenon known as…”
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SFAlab: image-based quantification of mechano-active ventral actin stress fibers in adherent cells by Mostert, Dylan, Grolleman, Janine, van Turnhout, Mark C., Groenen, Bart G. W., Conte, Vito, Sahlgren, Cecilia M., Kurniawan, Nicholas A., Bouten, Carlijn V. C.

“…Ventral actin stress fibers (SFs) are a subset of actin SFs that begin and terminate at focal adhesion (FA) complexes. Ventral SFs can transmit forces from and…”
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Behavior of CMPCs in unidirectional constrained and stress-free 3D hydrogels by van Marion, Mieke H, Bax, Noortje A.M, van Turnhout, Mark.C, Mauretti, Arianna, van der Schaft, Daisy W.J, Goumans, Marie José. T.H, Bouten, Carlijn V.C

“…Abstract Cardiomyocyte progenitor cells (CMPCs) are a candidate cell source for cardiac regenerative therapy. However, like other stem cells, after…”
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Postnatal development of collagen structure in ovine articular cartilage by Turnhout, M.C. van, Schipper, H, Engel, B, Buist, W, Kranenbarg, S, Leeuwen, J.L. van

“…Articular cartilage (AC) is the layer of tissue that covers the articulating ends of the bones in diarthrodial joints. Across species, adult AC shows an…”
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There is an individual tolerance to mechanical loading in compression induced deep tissue injury by Traa, Willeke A., van Turnhout, Mark C., Nelissen, Jules L., Strijkers, Gustav J., Bader, Dan L., Oomens, Cees W.J.

“…Deep tissue injury is a type of pressure ulcer which originates subcutaneously due to sustained mechanical loading. The relationship between mechanical…”
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Single‐Cell Profiling Reveals Functional Heterogeneity and Serial Killing in Human Peripheral and Ex Vivo‐Generated CD34+ Progenitor‐Derived Natural Killer Cells by Subedi, Nikita, Verhagen, Liesbeth Petronella, Jonge, Paul, Van Eyndhoven, Laura C., Turnhout, Mark C., Koomen, Vera, Baudry, Jean, Eyer, Klaus, Dolstra, Harry, Tel, Jurjen

“…Increasing evidence suggests that natural killer (NK) cells are composed of distinct functional subsets. This multifunctional role has made them an attractive…”
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Biomaterial screening of protein coatings and peptide additives: towards a simple synthetic mimic of a complex natural coating for a bio-artificial kidney by van Gaal, Ronald C, Vrehen, Annika F, van Sprang, Johnick F, Fransen, Peter-Paul K H, van Turnhout, Mark C, Dankers, Patricia Y W

“…Bio-artificial kidneys require conveniently synthesized membranes providing signals that regulate renal epithelial cell function. Therefore, we aimed to find…”
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Shape‐Morphing Photoresponsive Hydrogels Reveal Dynamic Topographical Conditioning of Fibroblasts by Bril, Maaike, Saberi, Aref, Jorba, Ignasi, van Turnhout, Mark C., Sahlgren, Cecilia M., Bouten, Carlijn V.C., Schenning, Albert P.H.J., Kurniawan, Nicholas A.

“…The extracellular environment defines a physical boundary condition with which cells interact. However, to date, cell response to geometrical environmental…”
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MRI based 3D finite element modelling to investigate deep tissue injury by Traa, Willeke A, van Turnhout, Mark C, Moerman, Kevin M, Nelissen, Jules L, Nederveen, Aart J, Strijkers, Gustav J, Bader, Dan L, Oomens, Cees W J

“…Pressure ulcers occur due to sustained mechanical loading. Deep tissue injury is a severe type of pressure ulcer, which is believed to originate in…”
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Deformation thresholds for chondrocyte death and the protective effect of the pericellular matrix by de Vries, Stefan A H, van Turnhout, Mark C, Oomens, Cees W J, Erdemir, Ahmet, Ito, Keita, van Donkelaar, Corrinus C

“…In cartilage tissue engineering studies, the stimulatory effect of mechanical perturbation declines after the first 2 weeks of culture. Similarly, it is known…”
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Modeling optical behavior of birefringent biological tissues for evaluation of quantitative polarized light microscopy by van Turnhout, Mark C, Kranenbarg, Sander, van Leeuwen, Johan L

“…Quantitative polarized light microscopy (qPLM) is a popular tool for the investigation of birefringent architectures in biological tissues. Collagen, the most…”
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Contribution of postnatal collagen reorientation to depth-dependent mechanical properties of articular cartilage by van Turnhout, Mark C., Kranenbarg, Sander, van Leeuwen, Johan L.

“…The collagen fibril network is an important factor for the depth-dependent mechanical behaviour of adult articular cartilage (AC). Recent studies show that…”
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Postnatal development of depth-dependent collagen density in ovine articular cartilage by van Turnhout, Mark C, Schipper, Henk, van Lagen, Barend, Zuilhof, Han, Kranenbarg, Sander, van Leeuwen, Johan L

“…Articular cartilage (AC) is the layer of tissue that covers the articulating ends of the bones in diarthrodial joints. Adult AC is characterised by a…”
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Modeling optical behavior of birefringent biological tissues for evaluation of quantitative polarized light microscopy by van Turnhout, Mark C., Kranenbarg, Sander, van Leeuwen, Johan L.

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Post natal development of articular cartilage mechanics by Turnhout, Mark C. Van, Kranenbarg, Sander, Van Leeuwen, Johan L.

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