Search Results - "van Thuijl, Hinke F."
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IDH mutation status and role of WHO grade and mitotic index in overall survival in grade II–III diffuse gliomas
Published in Acta neuropathologica (01-04-2015)“…Diffuse gliomas are up till now graded based upon morphology. Recent findings indicate that isocitrate dehydrogenase (IDH) mutation status defines biologically…”
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2
Clinical outcome assessment in patients with epilepsy: The value of health-related quality of life measurements
Published in Epilepsy research (01-02-2024)“…This narrative review provides an overview of the current knowledge on health-related quality of life (HRQOL), a relevant clinical outcome in patients with…”
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3
Clinical value of chromosome arms 19q and 11p losses in low-grade gliomas
Published in Neuro-oncology (Charlottesville, Va.) (01-03-2014)“…Diffuse low-grade gliomas (LGGs) form a heterogeneous subgroup of gliomas in adults. Chromosome (chr) arms 1p/19q codeletion and IDH mutation have been shown…”
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4
DNA copy number analysis of fresh and formalin-fixed specimens by shallow whole-genome sequencing with identification and exclusion of problematic regions in the genome assembly
Published in Genome research (01-12-2014)“…Detection of DNA copy number aberrations by shallow whole-genome sequencing (WGS) faces many challenges, including lack of completion and errors in the human…”
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Spatial and temporal evolution of distal 10q deletion, a prognostically unfavorable event in diffuse low-grade gliomas
Published in Genome biology (23-09-2014)“…The disease course of patients with diffuse low-grade glioma is notoriously unpredictable. Temporal and spatially distinct samples may provide insight into the…”
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Long-term wellbeing and neurocognitive functioning of diffuse low-grade glioma patients and their caregivers: A longitudinal study spanning two decades
Published in Neuro-oncology (Charlottesville, Va.) (14-02-2023)“…While patients with diffuse low-grade glioma (LGG) often survive for years, there is a risk of tumor progression which may impact patients' long-term…”
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Evolution of DNA repair defects during malignant progression of low-grade gliomas after temozolomide treatment
Published in Acta neuropathologica (01-04-2015)“…Temozolomide (TMZ) increases the overall survival of patients with glioblastoma (GBM), but its role in the clinical management of diffuse low-grade gliomas…”
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The effect of modafinil on fatigue, cognitive functioning, and mood in primary brain tumor patients: a multicenter randomized controlled trial
Published in Neuro-oncology (Charlottesville, Va.) (01-10-2013)“…Fatigue, cognitive deficits, and depression are frequently reported but often undertreated symptoms that can profoundly affect daily life in patients with…”
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Erratum to: TP53 and p53 statuses and their clinical impact in diffuse low grade gliomas
Published in Journal of neuro-oncology (01-08-2014)Get full text
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TP53 and p53 statuses and their clinical impact in diffuse low grade gliomas
Published in Journal of neuro-oncology (01-05-2014)“…TP53 is a pivotal gene frequently mutated in diffuse gliomas and particularly in astrocytic tumors. The majority of studies dedicated to TP53 in gliomas were…”
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Abstract 3426: A novel approach to copy number assessment by whole genome sequencing reveals extensive spatial heterogeneity in diffuse low-grade glioma
Published in Cancer research (Chicago, Ill.) (01-10-2014)“…Introduction: The disease course of patients with diffuse low-grade gliomas (LGGs) is notoriously unpredictable. Detailed analysis of the genetic make-up is…”
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