Search Results - "van Strien, Jolinde"

Kinetic Analysis of PRMT1 Reveals Multifactorial Processivity and a Sequential Ordered Mechanism by Brown, Jennifer I., Koopmans, Timo, van Strien, Jolinde, Martin, Nathaniel I., Frankel, Adam

“…Arginine methylation is a prevalent post‐translational modification in eukaryotic cells. Two significant debates exist within the field: do these enzymes…”
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Bet v 1-displaying elastin-like polypeptide nanoparticles induce a strong humoral and weak CD4+ T-cell response against Bet v 1 in a murine immunogenicity model by van Strien, Jolinde, Warmenhoven, Hans, Logiantara, Adrian, Makurat, Max, Aglas, Lorenz, Bethanis, Athanasios, Leboux, Romain, van Rijt, Leonie, MacKay, J Andrew, van Schijndel, Johannes W, Schneider, Gregory, Olsthoorn, René, Jiskoot, Wim, van Ree, Ronald, Kros, Alexander

“…There is growing concern about the toxicity of colloidal aluminum salts used as adjuvants in subcutaneous allergen immunotherapy (SCIT). Therefore, alternative…”
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Cationic liposomes bearing Bet v 1 by coiled coil-formation are hypo-allergenic and induce strong immunogenicity in mice by Warmenhoven, Hans, Leboux, Romain, Bethanis, Athanasios, van Strien, Jolinde, Logiantara, Adrian, van Schijndel, Hans, Aglas, Lorenz, van Rijt, Leonie, Slütter, Bram, Kros, Alexander, Jiskoot, Wim, van Ree, Ronald

“…Although aluminum hydroxide (alum) is widely accepted and used as safe vaccine adjuvant, there is some concern about possible toxicity upon long-lasting…”
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Elastin-like polypeptide-based micelles as a promising platform in nanomedicine by van Strien, Jolinde, Escalona-Rayo, Oscar, Jiskoot, Wim, Slütter, Bram, Kros, Alexander

“…New and improved nanomaterials are constantly being developed for biomedical purposes. Nanomaterials based on elastin-like polypeptides (ELPs) have…”
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Drug-tolerant detection of anti-drug antibodies in an antigen-binding assay using europium chelate fluorescence by van Strien, Jolinde, Dijk, Lisanne, Atiqi, Sadaf, Schouten, Rogier, Bloem, Karien, Wolbink, Gerrit Jan, Loeff, Floris, Rispens, Theo

“…Accurate anti-drug antibody (ADA) measurements in patient sera requires dissociation of ADA-drug complexes combined with sensitive and specific ADA detection…”
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Noncovalent Conjugation of OVA323 to ELP Micelles Increases Immune Response by van Strien, Jolinde, Makurat, Max, Zeng, Ye, Olsthoorn, René, Schneider, Gregory F., Slütter, Bram, MacKay, J. Andrew, Jiskoot, Wim, Kros, Alexander

“…Subunit vaccines would benefit from a safe particle-based adjuvant. Elastin-like polypeptide (ELP)-based micelles are interesting candidate adjuvants due to…”
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Kinetic Analysis of PRMT1 Reveals Multifactorial Processivity and a Sequential Ordered Mechanism by Brown, Jennifer I., Koopmans, Timo, Strien, Jolinde, Martin, Nathaniel I., Frankel, Adam

“…BACKGROUND Protein arginine N‐methyltransferases (PRMTs) are responsible for the transfer of one or two methyl groups from the methyl donor…”
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Cover Feature: Kinetic Analysis of PRMT1 Reveals Multifactorial Processivity and a Sequential Ordered Mechanism (ChemBioChem 1/2018) by Brown, Jennifer I., Koopmans, Timo, van Strien, Jolinde, Martin, Nathaniel I., Frankel, Adam

“…The cover feature picture shows the cofactor SAM (teal) and the peptide binding groove (pink) within a PRMT1 dimer. We find that PRMT1 binds its substrates by…”
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