Search Results - "van Straaten, Henny"

Ciliation and gene expression distinguish between node and posterior notochord in the mammalian embryo by Blum, Martin, Andre, Philipp, Muders, Kerstin, Schweickert, Axel, Fischer, Anja, Bitzer, Eva, Bogusch, Susanne, Beyer, Tina, van Straaten, Henny W.M., Viebahn, Christoph

“…The mammalian node, the functional equivalent of the frog dorsal blastoporal lip (Spemann's organizer), was originally described by Viktor Hensen in 1876 in…”
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Cellular concentrations of glutamine synthetase in murine organs by van Straaten, Henny W M, He, Youji, van Duist, Marjan M, Labruyère, Wil T, Vermeulen, Jacqueline L M, van Dijk, Paul J, Ruijter, Jan M, Lamers, Wouter H, Hakvoort, Theodorus B M

“…Glutamine synthetase (GS) is the only enzyme that can synthesize glutamine, but it also functions to detoxify glutamate and ammonia. Organs with high cellular…”
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Spinal congenital dermal sinus in a chick embryo model : Laboratory investigation by VAN AALST, Jasper, BOSELIE, Toon F. M, BEULS, Emile A. M, VLES, Johan S. H, VAN STRAATEN, Henny W. M

“…The origin of spinal congenital dermal sinuses is not known. A local nondisjunction of the closing neural tube and the epidermal ectoderm is thought to be the…”
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Over-expression of Grhl2 causes spina bifida in the Axial defects mutant mouse by BROUNS, Madeleine R, DE CASTRO, Sandra C. P, KÖHLER, Eleonore, VAN STRAATEN, Henny W, COPP, Andrew J, GREENE, Nicholas D. E, TERWINDT-ROUWENHORST, Els A, MASSA, Valentina, HEKKING, Johan W, HIRST, Caroline S, SAVERY, Dawn, MUNTS, Chantal, PARTRIDGE, Darren, LAMERS, Wout

“…Cranial neural tube defects (NTDs) occur in mice carrying mutant alleles of many different genes, whereas isolated spinal NTDs (spina bifida) occur in fewer…”
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Morphogenetic movements during cranial neural tube closure in the chick embryo and the effect of homocysteine by Brouns, Madeleine R, Afman, Lydia A, Vanhauten, Bart A M, Hekking, Johan W M, Köhler, Eleonore S, van Straaten, Henny W M

“…In order to unravel morphogenetic mechanisms involved in neural tube closure, critical cell movements that are fundamental to remodelling of the cranial neural…”
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Analysis of the embryonic phenotype of Bent tail, a mouse model for X-linked neural tube defects by Franke, Barbara, Klootwijk, Riko, Hekking, Johan W M, de Boer, Roelie T, ten Donkelaar, Hans J, Mariman, Edwin C M, van Straaten, Henny W M

“…Neural tube defects, mostly believed to result from closure defects of the neural tube during embryonic development, are frequently observed congenital…”
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Folate, homocysteine and neural tube defects: an overview by van der Put, N M, van Straaten, H W, Trijbels, F J, Blom, H J

“…Folate administration substantially reduces the risk on neural tube detects (NTD). The interest for studying a disturbed homocysteine (Hcy) metabolism in…”
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Inhibition of methylation and changes in gene expression in relation to neural tube defects by van der Linden, Ivon J. M., Heil, Sandra G., van Egmont Petersen, Michael, van Straaten, Henny W., Heijer, Martin den, Blom, Henk J.

“…BACKGROUND: An impaired DNA methylation has been suggested to underlie the complex etiology of neural tube defects (NTDs). Previously, we have demonstrated…”
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Differences in axial curvature correlate with species-specific rate of neural tube closure in embryos of chick, rabbit, mouse, rat and human by Peeters, M C, Hekking, J W, Shiota, K, Drukker, J, Van Straaten, H W

“…Studies on the mouse strain curly tail, a mutant for neural tube defects, have indicated that axial curvature is an important factor in neural tube closure…”
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Spatio-temporal curvature pattern of the caudal body axis for non-mutant and curly tail mouse embryos during the period of caudal neural tube closure by Peeters, M C, Hekking, W M, Vainas, T, Drukker, J, van Straaten, H W

“…During the period of early organogenesis the mouse embryo has a curved body shape, which is thought to interact with ongoing developmental processes. Curly…”
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Abnormalities of floor plate, notochord and somite differentiation in the loop-tail ( Lp) mouse: a model of severe neural tube defects by Greene, Nicholas D.E, Gerrelli, Dianne, Van Straaten, Henny W.M, Copp, Andrew J

“…Mouse embryos homozygous for the loop-tail ( Lp) mutation fail to initiate neural tube closure at E8.5, leading to a severe malformation in which the neural…”
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Multistep role for actin in initial closure of the mesencephalic neural groove in the chick embryo by Van Straaten, Henny W.M., Sieben, Inge, Hekking, Johan W.M.

“…In a previous study, we have demonstrated that initial closure of the mesencephalic neural groove in the chick embryo is different from neurulation elsewhere…”
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Inhibition of transmethylation disturbs neurulation in chick embryos by Afman, Lydia A., Blom, Henk J., Drittij, Marie-Jose, Brouns, Madeleine R., van Straaten, Henny W.M.

“…Periconceptional folic acid supplementation can reduce the occurrence of neural tube defects. A low folate status will result in reduced remethylation of…”
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Toward positional cloning of the curly tail gene by Brouns, Madeleine R., Peeters, Marian C.E., Geurts, Jan M., Merckx, Diane M., Engelen, John J., Hekking, Johan W.M., Terwindt-Rouwenhorst, Els A.W., Oosterbaan, Mariet E.A.C., Geraedts, Joep P.M., van Straaten, Henny W.

“…BACKGROUND The curly tail (ct) mutant mouse is one of the best‐studied mouse models of spina bifida. The ct mutation has been localized to distal chromosome 4…”
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Curvature of the caudal region is responsible for failure of neural tube closure in the curly tail (ct) mouse embryo by BROOK, F. A, SHUMP, A. S. W, VAN STRAATEN, H. W. M, COPP, A. J

“…Delayed closure of the posterior neuropore (PNP) occurs to a variable extent in homozygous mutant curly tail (ct) mouse embryos, and results in the development…”
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Dietary methionine does not reduce penetrance in curly tail mice but causes a phenotype-specific decrease in embryonic growth by van Straaten, H W, Blom, H, Peeters, M C, Rousseau, A M, Cole, K J, Seller, M J

“…The mouse mutation, curly tail, has incomplete penetrance and variable expression. Approximately 60% of the mice have a curly tail (CT), from which up to 20%…”
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Role of differential cell proliferation in the tail bud in aberrant mouse neurulation by Peeters, Marian C.E., Schutte, Bert, Lenders, Marie‐Hélène J.N., Hekking, Johan W.M., Drukker, Jan, Straaten, Henny W.M. Van

“…In the mouse mutant curly tail, the phenotypes spina bifida and curled tail result from a delay in closure of the posterior neuropore (PNP). At the…”
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Hyaluronan Disappears Intercellularly and Appears at the Basement Membrane Region during Formation of Embryonic Epithelia: mouse embryo/hyaluronan/epithelium/basement membrane/development by van Straaten, Henny W. M., Hooper, Kevin C., Bernfield, Merton

“…The distribution of tissue hyaluronan has been assessed in the neuraxial region of 8.5 to 10.5 day mouse embryos using a fragment of bovine nasal cartilage…”
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Curly tail: a 50-year history of the mouse spina bifida model by van Straaten, H W, Copp, A J

“…This paper reviews 50 years of progress towards understanding the aetiology and pathogenesis of neural tube defects (NTD) in the curly tail (ct) mutant mouse…”
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Models of neural tube defects by Brouns, Madeleine R., van Straaten, Henny W.M.

“…Neural tube defects are debilitating malformations that result from the failure of the neural tube to close. Depending on the axial level of the defect, this…”
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