Search Results - "van Scott, M R"

IL-10 gene knockout attenuates allergen-induced airway hyperresponsiveness in C57BL/6 mice by Justice, J P, Shibata, Y, Sur, S, Mustafa, J, Fan, M, Van Scott, M R

“…Intratracheal administration of interleukin-10 (IL-10) has been reported to inhibit allergic inflammation but augment airway hyperresponsiveness (AHR). In the…”
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Ragweed-induced expression of GATA-3, IL-4, and IL-5 by eosinophils in the lungs of allergic C57BL/6J mice by Justice, J Paul, Borchers, M T, Lee, J J, Rowan, W H, Shibata, Y, Van Scott, M R

“…Allergen-induced recruitment of T lymphocytes and eosinophils to the airways is associated with increased expression of the transcription factor GATA-3. In…”
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Modelling asthma in macaques: longitudinal changes in cellular and molecular markers by AYANOGLU, G, DESAI, B, WARDLE, R. L, FICK, R. B, GREIN, J, DE WAAL MALEFYT, R, MATTSON, J, MCCLANAHAN, T, OLMSTEAD, S, REECE, S. P, VAN SCOTT, M. R

“…The aim of the present study was to determine whether systemic sensitisation and chronic aeroallergen challenge in macaques replicate the classical and…”
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Th1 Adjuvant N-Acetyl-d-Glucosamine Polymer Up-Regulates Th1 Immunity but Down-Regulates Th2 Immunity against a Mycobacterial Protein (MPB-59) in Interleukin-10-Knockout and Wild-Type Mice by SHIBATA, Yoshimi, HONDA, Ikuro, JUSTICE, J. Paul, VAN SCOTT, Michael R, NAKAMURA, Reiko M, MYRVIK, Quentin N

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Ion Transport by Rabbit Nonciliated Bronchiolar Epithelial Cells (Clara Cells) in Culture by Van Scott, Michael R., Hester, Susan, Boucher, Richard C.

“…The functions of epithelia that line small airways in mammalian lungs are unknown. To gain insight into the role of small-airway epithelia in lung liquid…”
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Culture of airway epithelial cells: research techniques by Van Scott, M R, Yankaskas, J R, Boucher, R C

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Purinergic regulation of ion transport across nonciliated bronchiolar epithelial (Clara) cells by Van Scott, M R, Chinet, T C, Burnette, A D, Paradiso, A M

“…Previous studies demonstrated that elevation of intracellular calcium concentration ([Ca2+]i) increased electrogenic anion transport by bronchiolar epithelia…”
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Sodium- and chloride-conductive pathways in cultured mouse tracheal epithelium by Clarke, L L, Burns, K A, Bayle, J Y, Boucher, R C, Van Scott, M R

“…The utility of a transgenic murine model of cystic fibrosis (CF) lung disease will likely depend on whether the mouse's proximal airway epithelium is…”
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IL-10 reduces Th2 cytokine production and eosinophilia but augments airway reactivity in allergic mice by van Scott, M R, Justice, J P, Bradfield, J F, Enright, E, Sigounas, A, Sur, S

“…We investigated the effects of interleukin (IL)-10 administration on allergen-induced Th2 cytokine production, eosinophilic inflammation, and airway…”
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Differential effects of polycationic protein on Cl- secretory and Na+ absorptive airways by Smith, M D, Penland, C M, Van Scott, M R

“…Effects of cationic proteins on electrolyte transport depend on the specific channels and electrochemical driving forces expressed by epithelia. The…”
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Beta-adrenergic regulation of Cl- and HCO3- secretion by Clara cells by Van Scott, M R, Penland, C M, Welch, C A, Lazarowski, E

“…Previous studies on beta-adrenergic agonist regulation of ion transport in distal airways yielded discordant results. The present study was performed to…”
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MUCOSAL IL-12 INHIBITS AIRWAY REACTIVITY TO METHACHOLINE AND RESPIRATORY FAILURE IN MURINE ASTHMA by Sanjiv Sur, Page Bouchard, Don Holbert, Michael R. Van Scott

“…The worldwide incidence, prevalence, and fatality rates from asthma are increasing despite currently available therapeutic modalities. Systemic administration…”
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Effect of hormones on growth and function of cultured canine tracheal epithelial cells by Van Scott, M R, Lee, N P, Yankaskas, J R, Boucher, R C

“…Insulin (INS), endothelial cell growth supplement (ECGS), transferrin (TF), cholera toxin (CT), hydrocortisone (HC), triiodothyronine (T3), and epidermal…”
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Epithelial modulation of afferent nerve endings: differential effects of amiloride on afferent subtypes by Ghosh, T K, Van Scott, M R, Mathew, O P

“…Mechanisms underlying the differing chemosensitivity of laryngeal afferents have not been defined. The role of airway epithelium in transducing the chemical…”
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Bioelectric response of human nasal epithelial cells to polycationic protein by Van Scott, M R, Smith, M D, Welch, C A, Bentzel, C, Metzger, W J

“…Polycationic proteins alter electrolyte transport by epithelium and endothelium, and in asthma are thought to disrupt the airway epithelium and contribute to…”
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Immunoregulatory roles of IL-10 in innate immunity: IL-10 inhibits macrophage production of IFN-gamma-inducing factors but enhances NK cell production of IFN-gamma by Shibata, Y, Foster, L A, Kurimoto, M, Okamura, H, Nakamura, R M, Kawajiri, K, Justice, J P, Van Scott, M R, Myrvik, Q N, Metzger, W J

“…In our study of the immunoregulatory roles of IL-10 in innate immunity, nonantigenic phagocytosable chitin particles were administered i.v. to IL-10-deficient…”
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Mucosal IL-12 is more effective than systemic IL-12 in augmenting IFN-γ expression and inhibiting allergic lung eosinophilia in murine lungs by SUR, Sanjiv, CHOUDHURY, Barun K, LAM, John Simon, BOUCHARD, Page, WILD, James S, SUR, Nilanjana, ALAM, Rafeul, SIGOUNAS, Anastasia, HOLBERT, Don, VAN SCOTT, Michael R

“…The relative efficacy of mucosal (intratracheal) and systemic (intraperitoneal) delivery of interleukin (IL)-12 was evaluated in a mouse model of allergic lung…”
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Na+ and Cl- transport across rabbit nonciliated bronchiolar epithelial (Clara) cells by Van Scott, M R, Davis, C W, Boucher, R C

“…Radioisotopic flux measurements were performed on rabbit Clara cell epithelium cultured in serum-free hormone-supplemented medium to identify the major ion…”
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Intracellular Ca2+ and regulation of ion transport across rabbit Clara cells by Van Scott, M R, Paradiso, A M

“…We investigated whether Ca2+ was involved in regulation of ion transport across rabbit distal airway epithelial cells by studying the effects that elevation of…”
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Characterization of Endothelin Release from Guinea-pig Tracheal Epithelium: Influence of Proinflammatory Mediators Including Major Basic Protein by Hay, D.W.P., Van Scott, M.R., Muccitelli, R.M.

“…The characteristics of endothelin (ET) release from guinea-pig tracheal epithelium were investigated, including examination of the effects of several…”
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