Search Results - "van Scharrenburg, Guus"

Nasal or intramuscular immunization of mice with influenza subunit antigen and the B subunit of Escherichia coli heat-labile toxin induces IgA- or IgG-mediated protective mucosal immunity by Haan, Lolke de, Verweij, Willem R, Holtrop, Marijke, Brands, Ruud, van Scharrenburg, Guus J.M, Palache, Abraham M, Agsteribbe, Etienne, Wilschut, Jan

“…Local mucosal IgA antibodies play a central role in protection of the respiratory tract against influenza virus infection. Therefore, new-generation influenza…”
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GMP production of [68Ga]Ga-BOT5035 for imaging of liver fibrosis in microdosing phase 0 study by Velikyan, Irina, Doverfjord, Johan G., Estrada, Sergio, Steen, Herman, Van Scharrenburg, Guus, Antoni, Gunnar

“…Early detection of liver fibrosis and monitoring response to treatment crucial for the management of patients are currently not feasible in clinical practice…”
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Detection of Experimental Colorectal Peritoneal Metastases by a Novel PDGFRβ-Targeting Nanobody by Strating, Esther, Elias, Sjoerd, van Scharrenburg, Guus, Luoto, Kaisa, Verheem, André, Borel Rinkes, Inne, Steen, Herman, Kranenburg, Onno

“…Peritoneal metastases in colorectal cancer (CRC) belong to Consensus Molecular Subtype 4 (CMS4) and are associated with poor prognosis. Conventional imaging…”
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Piperazinyl oxime ethers as NK-1 receptor antagonists by van den Hoogenband, Adri, van Maarseveen, Jan H., McCreary, Andrew C., Mulder, Arie T., van Scharrenburg, Guus J.M., van Stuivenberg, Herman H., Zethof, Theo J.J., Zijta, Barbara, Iwema Bakker, Wouter I.

“…The synthesis and SAR for a new class of centrally active NK-1 receptor antagonists are described. The new compounds all have a piperazinyl oxime ether…”
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Double-blind study of pardoprunox, a new partial dopamine agonist, in early Parkinson's disease by Bronzova, Juliana, Sampaio, Cristina, Hauser, Robert A., Lang, Anthony E., Rascol, Olivier, Theeuwes, Ad, van de Witte, Serge V., van Scharrenburg, Guus

“…This study examined the efficacy and safety of the partial dopamine agonist, pardoprunox (SLV308), in the treatment of patients with early Parkinson's disease…”
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In vitro characterization of SLV308 (7-[4-methyl-1-piperazinyl]-2(3H)-benzoxazolone, monohydrochloride): A novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist by Glennon, Jeffrey C., Van Scharrenburg, Guus, Ronken, Eric, Hesselink, Mayke B., Reinders, Jan-Hendrik, Van Der Neut, Martina, Long, Stephen K., Feenstra, Rolf W., McCreary, Andrew C.

“…Present Parkinson's disease treatment strategies are far from ideal for a variety of reasons; it has therefore been suggested that partial dopamine receptor…”
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P-033 - Initial results of clinical phase 0 study on [68Ga]Ga-BOT5035/PET for the assessment of fibrosis activity by Velikyan, Irina, Runeson, Paul, Sigfridsson, Jonathan, Rorsman, Fredrik, Jonasson, My, Steen, Herman, van Scharrenburg, Guus, Antoni, Gunnar

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Initial results of clinical phase 0 study on [68Ga]Ga-BOT5035/PET for the assessment of fibrosis activity by Velikyan, Irina, Runeson, Paul, Sigfridsson, Jonathan, Rorsman, Fredrik, Jonasson, My, Steen, Herman, van Scharrenburg, Guus, Antoni, Gunnar

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Tonic inhibition by orphanin FQ/nociceptin of noradrenaline neurotransmission in the amygdala by Kawahara, Yukie, Hesselink, Mayke B., van Scharrenburg, Guus, Westerink, Ben H.C.

“…The present microdialysis study investigated whether nociceptin/orphanin FQ exerts a tonic inhibition of the release of noradrenaline in the basolateral…”
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Musosal immunoadjuvant activity of recombinant Escherichia coli heat-labile enterotoxin and its B subunit : Induction of systemic IgG and secretory IgA responses in mice by intranasal immunization with influenza virus surface antigen by VERWEIJ, W. R, DE HAAN, L, HOLTROP, M, AGSTERIBBE, E, BRANDS, R, VAN SCHARRENBURG, G. J. M, WILSCHUT, J

“…The Escherichia coli heat-labile enterotoxin (LT) is a very potent mucosal immunogen. LT also has strong adjuvant activity towards coadministered unrelated…”
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Musosal immunoadjuvant activity of recombinant Escherichia coli heatlabile enterotoxin and its B subunit: Induction of systemic IgG and secretory IgA responses in mice by intranasal immunization with influenza virus surface antigen by Verweij, Willem R, Haan, Lolke de, Holtrop, Marijke, Agsteribbe, Etienne, Brands, Ruud, van Scharrenburg, Guus J.M, Wilschut, Jan

“…The Escherichia coli heat-labile enterotoxin (LT) is a very potent mucosal immunogen. LT also has strong adjuvant activity towards coadministered unrelated…”
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Evaluation of a Liposome-Supplemented Intranasal Influenza Subunit Vaccine in a Murine Model System: Induction of Systemic and Local Mucosal Immunity by de Haan, Aalzen, Van Scharrenburg, Guus J.M., Masihi, K. Noel, Wilschut, Jan

“…Abstract This study reports on the mucosal immunoadjuvant activity of liposomes in an experimental influenza subunit vaccine administered intranasally (i.n.)…”
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Antigenic Relationships between Pore Proteins of Escherichia coli K12 by OVERBEEKE, Nico, SCHARRENBURG, Guus, LUGTENBERG, Ben

“…Antisera were raised against the purified Escherichia coli K12 outer membrane proteins ompA‐, ompC‐ and ompF proteins and protein e. Several immunological…”
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