Search Results - "van Roon, Marian A."

Cooperative action of Tbx2 and Nkx2.5 inhibits ANF expression in the atrioventricular canal: implications for cardiac chamber formation by Habets, Petra E M H, Moorman, Antoon F M, Clout, Danielle E W, van Roon, Marian A, Lingbeek, Merel, van Lohuizen, Maarten, Campione, Marina, Christoffels, Vincent M

“…During heart development, chamber myocardium forms locally from the embryonic myocardium of the tubular heart. The atrial natriuretic factor (ANF) gene is…”
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Overexpression of arginase I in enterocytes of transgenic mice elicits a selective arginine deficiency and affects skin, muscle, and lymphoid development by Jonge, Wouter J. de, Hallemeesch, Marcella M, Kwikkers, Karin L, Ruijter, Jan M, Gier-de Vries, Corrie de, Roon, Marian A. van, Meijer, Alfred J, Marescau, Bart, Deyn, Peter P. de, Deutz, Nicolaas E.P, Lamers, Wouter H

“…Background: Arginine is required for the detoxification of ammonia and the synthesis of proteins, nitric oxide, agmatine, creatine, and polyamines, and it may…”
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Anion Exchanger 2 Is Essential for Spermiogenesis in Mice by Medina, Juan F., Recalde, Sergio, Prieto, Jesús, Lecanda, Jon, Sáez, Elena, Funk, Colin D., Vecino, Paola, van Roon, Marian A., Ottenhoff, Roelof, Bosma, Piter J., Bakker, Conny T., Ronald P. J. Oude Elferink

“…Na+-independent anion exchangers (AE) mediate electroneutral exchange of Cl-for HCO3 -ions across cell membranes, being involved in intracellular pH and cell…”
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Adjunctive treatments for pneumococcal meningitis: a systematic review of experimental animal models by Koning, Rutger, van Roon, Marian A, Brouwer, Matthijs C, van de Beek, Diederik

“…New treatments are needed to improve the prognosis of pneumococcal meningitis. We performed a systematic review on adjunctive treatments in animal models of…”
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Conditional deletion of TGF-βR1 using Langerin-Cre mice results in Langerhans cell deficiency and reduced contact hypersensitivity by Zahner, Sonja P, Kel, Junda M, Martina, Cerithsa A E, Brouwers-Haspels, Inge, van Roon, Marian A, Clausen, Björn E

“…The critical role of Langerhans cells (LC) in contact hypersensitivity (CHS) was recently questioned in studies using different LC-depletion mouse models. On…”
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Overlap syndrome of cardiac sodium channel disease in mice carrying the equivalent mutation of human SCN5A-1795insD by REMME, Carol Ann, VERKERK, Arie O, CARMELIET, Peter, DE BAKKER, Jacques M. T, VELDKAMP, Marieke W, BEZZINA, Connie R, NUYENS, Dieter, VAN GINNEKEN, Antoni C. G, VAN BRUNSCHOT, Sandra, BELTERMAN, Charly N. W, WILDERS, Ronald, VAN ROON, Marian A, TAN, Hanno L, WILDE, Arthur A. M

“…Patients carrying the cardiac sodium channel (SCN5A) mutation 1795insD show sudden nocturnal death and signs of multiple arrhythmia syndromes including…”
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Generation of mice with a conditional null allele for Tbx2 by Wakker, Vincent, Brons, Janynke F., Aanhaanen, Wim T.J., van Roon, Marian A., Moorman, Antoon F.M., Christoffels, Vincent M.

“…The T‐box transcription factor Tbx2 plays important roles in patterning and development, and has been implicated in cell‐cycle regulation and cancer…”
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Adenosine-deaminase-deficient mice die perinatally and exhibit liver-cell degeneration, atelectasis and small intestinal cell death by Migchielsen, Alexandra A.J, Breuer, Marco L, van Roon, Marian A, Riele, Hein te, Zurcher, Chris, Ossendorp, Ferry, Toutain, Stephan, Hershfield, Michael S, Berns, Anton, Valerio, Dinko

“…We report the generation and characterization of mice lacking adenosine deaminase (ADA). In humans, absence of ADA causes severe combined immunodeficiency. In…”
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A Single Regulatory Module of the Carbamoylphosphate Synthetase I Gene Executes Its Hepatic Program of Expression by Christoffels, Vincent M., Habets, Petra E.M.H., Das, Atze T., Clout, Danielle E.W., van Roon, Marian A., Moorman, Antoon F.M., Lamers, Wouter H.

“…A 469-base pair (bp) upstream regulatory fragment (URF) and the proximal promoter of the carbamoylphosphate synthetase I (CPS) gene were analyzed for their…”
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Cardiac expression of Gal4 causes cardiomyopathy in a dose-dependent manner by Habets, Petra E M H, Clout, Danielle E W, Lekanne Deprez, Ronald H, van Roon, Marian A, Moorman, Antoon F M, Christoffels, Vincent M

“…Cardiac expression of a transgene is a common approach for determining the role of gene products in the processes underlying cardiomyopathy and heart failure…”
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Clinical features and prognostic factors in Covid-19: A prospective cohort study by de Bruin, Sanne, Bos, Lieuwe D., van Roon, Marian A., Tuip-de Boer, Anita M., Schuurman, Alex R., Koel-Simmelinck, Marleen J.A., Bogaard, Harm Jan, Tuinman, Pieter Roel, van Agtmael, Michiel A., Hamann, Jörg, Teunissen, Charlotte E., Wiersinga, W. Joost, (Koos) Zwinderman, A.H., Brouwer, Matthijs C., van de Beek, Diederik, Vlaar, Alexander P.J., van Agtmael, Michiel, Algera, Anne Geke, Appelman, Brent, van Baarle, Frank, Bax, Diane, Beudel, Martijn, Bogaard, Harm Jan, Bomers, Marije, Bonta, Peter, Bos, Lieuwe, Botta, Michela, de Brabander, Justin, de Bree, Godelieve, de Bruin, Sanne, Buis, David T.P., Bugiani, Marianna, Bulle, Esther, Chouchane, Osoul, Cloherty, Alex, de Rotte, Maurits C.F.J., Dijkstra, Mirjam, Dongelmans, Dave A., Dujardin, Romein W.G., Elbers, Paul, Fleuren, Lucas, Geerlings, Suzanne, Geijtenbeek, Theo, Girbes, Armand, Goorhuis, Bram, Grobusch, Martin P., Hafkamp, Florianne, Hagens, Laura, Hamann, Jorg, Harris, Vanessa, Hemke, Robert, Hermans, Sabine M., Heunks, Leo, Hollmann, Markus, Horn, Janneke, Hovius, Joppe W., de Jong, Menno D., Koning, Rutger, Lim, Endry H.T., van Mourik, Niels, Nellen, Jeannine, Nossent, Esther J., Paulus, Frederique, Peters, Edgar, Piña-Fuentes, Dan A.I., van der Poll, Tom, Preckel, Bennedikt, Prins, Jan M., Raasveld, Jorinde, Reijnders, Tom, Schinkel, Michiel, Schrauwen, Femke A.P., Schultz, Marcus J., Schuurmans, Alex, Schuurmans, Jaap, Sigaloff, Kim, Slim, Marleen A., Smeele, Patrick, Smit, Marry, Stijnis, Cornelis S., Stilma, Willemke, Teunissen, Charlotte, Thoral, Patrick, Tsonas, Anissa M., Tuinman, Pieter R., van der Valk, Marc, Veelo, Denise, Volleman, Carolien, de Vries, Heder, Vught, Lonneke A., van Vugt, Michèle, Wouters, Dorien, Zwinderman, A.H (Koos), Brouwer, Matthijs C., Wiersinga, W. Joost, Vlaar, Alexander P.J.

“…Mortality rates are high among hospitalized patients with COVID-19, especially in those intubated on the ICU. Insight in pathways associated with unfavourable…”
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The spatio-temporal control of the expression of glutamine synthetase in the liver is mediated by its 5'-enhancer by Lie-Venema, H, Labruyère, W T, van Roon, M A, de Boer, P A, Moorman, A F, Berns, A J, Lamers, W H

“…In previous studies of the glutamine synthetase gene, the promoter and two enhancer elements, one in the upstream region and one within the first intron, were…”
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The Upstream Regulatory Region of the Carbamoyl-phosphate Synthetase I Gene Controls Its Tissue-specific, Developmental, and Hormonal Regulation in Vivo by Christoffels, Vincent M., van den Hoff, Maurice J.B., Lamers, Marinus C., van Roon, Marian A., de Boer, Piet A.J., Moorman, Antoon F.M., Lamers, Wouter H.

“…The carbamoyl-phosphate synthetase I gene is expressed in the periportal region of the liver, where it is activated by glucocorticosteroids and glucagon (via…”
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Transgenic mice overexpressing human KvLQT1 dominant-negative isoform. Part I: Phenotypic characterisation by Demolombe, S, Lande, G, Charpentier, F, van Roon, M A, van den Hoff, M J, Toumaniantz, G, Baro, I, Guihard, G, Le Berre, N, Corbier, A, de Bakker, J, Opthof, T, Wilde, A, Moorman, A F, Escande, D

“…The KCNQ1 gene encodes the KvLQT1 potassium channel, which generates in the human heart the slow component of the cardiac delayed rectifier current, I(Ks)…”
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Overexpression of arginase I in enterocytes of transgenic mice elicits a selective arginine deficiency and affects skin, muscle, and lymphoid development1,2,3 by de Jonge, Wouter J, Hallemeesch, Marcella M, Kwikkers, Karin L, Ruijter, Jan M, de Gier-de Vries, Corrie, van Roon, Marian A, Meijer, Alfred J, Marescau, Bart, De Deyn, Peter P, Deutz, Nicolaas EP, Lamers, Wouter H

“…Arginine is required for the detoxification of ammonia and the synthesis of proteins, nitric oxide, agmatine, creatine, and polyamines, and it may promote…”
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Transgenic mice overexpressing human KvLQT1 dominant-negative isoform: Part I : Phenotypic characterisation: Spotlight issue on sudden cardiac death by DEMOLOMBE, Sophie, LANDE, Gilles, DE BAKKER, Jacques, OPTHOF, Tobias, WILDE, Arthur, MOORMAN, Antoon F. M, ESCANDE, Denis, CHARPENTIER, Flavien, VAN ROON, Marian A, VAN DEN HOFF, Maurice J. B, TOUMANIANTZ, Gilles, BARO, Isabelle, GUIHARD, Gilles, LE BERRE, Nathalie, CORBIER, Alain

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The Spatio-temporal Control of the Expression of Glutamine Synthetase in the Liver Is Mediated by Its 5′-Enhancer by Heleen Lie-Venema, T. Labruyère Wil, A. van Roon Marian, A. J. de Boer Piet, Antoon F. M. Moorman, Anton J. M. Berns, Wouter H. Lamers

“…In previous studies of the glutamine synthetase gene, the promoter and two enhancer elements, one in the upstream region and one within the first intron, were…”
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The Nucleotide sequences of the regions flanking the genes coding for 23S, 16S and 4.5S ribosomal RNA on cfaloroplast DNA from Spirodela oligorhiza by Keus, Ronald J.A., Dekker, Albert F., van Roon, Marian A., Groot, Gert S.P.

“…The nucleotide sequences of the flanking regions of the genes coding for Spirodela oligorhiza chloroplast ribosonal RNA's have been determined. We have…”
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Synthesis, accumulation and turnover of carbamoylphosphate synthetase and phospho enol pyruvate carboxykinase in cultures of embryonic rat hepatocytes by van ROON, Marian A., CHARLES, Robert, LAMERS, Wouter H.

“…Glucocorticosteroid, thyroid hormones and cyclic AMP can induce the synthesis of carbamoylphosphate synthetase and phospho enol pyruvate carboxykinase in…”
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Accumulation of carbamoylphosphate‐synthetase and phospho enol pyruvate‐carboxykinase mRNA in embryonic rat hepatocytes: Evidence for translational control during the initial phases of hepatocyte‐specific gene expression in vitro by van ROON, Marian A., ZONNEVELD, Duco, CHARLES, Robert, LAMERS, Wouter H.

“…The aim of this study was to establish whether the initial accumulation of hepatocyte‐specific proteins after hormone induction is regulated at the…”
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