Search Results - "van Rooij, H. C. J."

The mouse androgen receptor. Functional analysis of the protein and characterization of the gene by FABER, P. W, KING, A, VAN ROOIJ, H. C. J, BRINKMANN, A. O, DE BOTH, N. J, TRAPMAN, J

“…Screening a mouse genomic DNA library with human androgen-receptor (hAR) cDNA probes resulted in the isolation and characterization of eight genomic fragments…”
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Aberrant Splicing of Androgen Receptor mRNA Results in Synthesis of a Nonfunctional Receptor Protein in a Patient with Androgen Insensitivity by Ris-Stalpers, C., G. G. J. M. Kuiper, Faber, P. W., Schweikert, H. U., van Rooij, H. C. J., Zegers, N. D., Hodgins, M. B., Degenhart, H. J., Trapman, J., Brinkmann, A. O.

“…Androgen insensitivity is a disorder in which the correct androgen response in an androgen target cell is impaired. The clinical symptoms of this X…”
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Substitution of aspartic acid-686 by histidine or asparagine in the human androgen receptor leads to a functionally inactive protein with altered hormone-binding characteristics by Ris-Stalpers, C, Trifiro, M A, Kuiper, G G, Jenster, G, Romalo, G, Sai, T, van Rooij, H C, Kaufman, M, Rosenfield, R L, Liao, S

“…We have identified two different single nucleotide alterations in codon 686 (GAC; aspartic acid) in exon 4 of the human androgen receptor gene in three…”
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A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-androgens by Veldscholte, J, Ris-Stalpers, C, Kuiper, G G, Jenster, G, Berrevoets, C, Claassen, E, van Rooij, H C, Trapman, J, Brinkmann, A O, Mulder, E

“…LNCaP prostate tumor cells contain an abnormal androgen receptor system. Progestagens, estradiol and anti-androgens can compete with androgens for binding to…”
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Cloning, structure and expression of a cDNA encoding the human androgen receptor by Trapman, J, Klaassen, P, Kuiper, G G, van der Korput, J A, Faber, P W, van Rooij, H C, Geurts van Kessel, A, Voorhorst, M M, Mulder, E, Brinkmann, A O

“…A cDNA clone has been isolated from a library prepared of mRNA of human breast cancer T47D cells with an oligonucleotide probe homologous to part of the region…”
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The human androgen receptor: domain structure, genomic organization and regulation of expression by Brinkmann, A O, Faber, P W, van Rooij, H C, Kuiper, G G, Ris, C, Klaassen, P, van der Korput, J A, Voorhorst, M M, van Laar, J H, Mulder, E

“…The domain structure and the genomic organization of the human androgen receptor (hAR) has been studied after molecular cloning and characterization of cDNA…”
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Unusual specificity of the androgen receptor in the human prostate tumor cell line LNCaP: high affinity for progestagenic and estrogenic steroids by Veldscholte, J, Voorhorst-Ogink, M M, Bolt-de Vries, J, van Rooij, H C, Trapman, J, Mulder, E

“…LNCaP tumor cells, derived from a metastatic lesion of a human prostatic carcinoma, are androgen-sensitive in cell culture. Although increase in growth rate is…”
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Characterization of the human androgen receptor transcription unit by FABER, P. W, VAN ROOIJ, H. C. J, VAN DER KORPUT, H. A. G. M, BAARENDS, W. M, BRINKMANN, A. O, GROOTEGOED, J. A, TRAPMAN, J

“…A full length human androgen receptor (hAR) cDNA was constructed from cDNA and genomic clones. Structurally the 10.6-kilobase (kb) hAR cDNA consists of a long…”
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Endotoxin stimulates glycogenolysis in the liver by means of intercellular communication by Casteleijn, E, Kuiper, J, Van Rooij, H C, Kamps, J A, Koster, J F, Van Berkel, T J

“…Escherichia coli endotoxin (lipopolysaccharide) was shown to increase glycogenolysis in the perfused liver 2-3-fold. In isolated parenchymal liver cells,…”
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The N-terminal domain of the human androgen receptor is encoded by one, large exon by Faber, P W, Kuiper, G G, van Rooij, H C, van der Korput, J A, Brinkmann, A O, Trapman, J

“…Using specific cDNA hybridization probes, the first coding exon of the human androgen receptor gene was isolated from a genomic library. The exon contained an…”
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Hormonal control of glycogenolysis in parenchymal liver cells by Kupffer and endothelial liver cells by Casteleijn, E, Kuiper, J, van Rooij, H C, Kamps, J A, Koster, J F, van Berkel, T J

“…Conditioned media of isolated Kupffer and endothelial liver cells were added to incubations of parenchymal liver cells, in order to test whether secretory…”
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Structural organization of the human androgen receptor gene by Kuiper, G G, Faber, P W, van Rooij, H C, van der Korput, J A, Ris-Stalpers, C, Klaassen, P, Trapman, J, Brinkmann, A O

“…The complete coding region of the human androgen receptor gene has been isolated from a genomic library. The information for the androgen receptor was found to…”
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Two different, overlapping pathways of transcription initiation are active on the TATA-less human androgen receptor promoter : the role of Spl by FABER, P. W, VAN ROOIJ, H. C. J, SCHIPPER, H. J, BRINKMANN, A. O, TRAPMAN, J

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Prostaglandin D2 mediates the stimulation of glycogenolysis in the liver by phorbol ester by Casteleijn, E, Kuiper, J, Van Rooij, H C, Kamps, J A, Koster, J F, Van Berkel, T J

“…The tumour-promoting phorbol ester, phorbol 12-myristate 13-acetate (PMA), when added to the perfused liver, stimulates glycogenolysis 2-fold. This stimulation…”
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Androgen receptor abnormalities by Brinkmann, A O, Kuiper, G G, Ris-Stalpers, C, van Rooij, H C, Romalo, G, Trifiro, M, Mulder, E, Pinsky, L, Schweikert, H U, Trapman, J

“…The human androgen receptor is a member of the superfamily of steroid hormone receptors. Proper functioning of this protein is a prerequisite for normal male…”
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Mechanism of glucagon stimulation of fructose-1,6-bisphosphatase in rat hepatocytes: involvement of a low-MDr activator by CASTELEIJN, E, VAN ROOIJ, H. C. J, VAN BERKEL, T. J. C, KOSTER, J. F

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Enhancement and suppression of DTH reactivity to Rauscher murine leukaemia virus induced tumour cell lines by KNULST, A. C, BERENDS, D, BAZUIN, C, VAN ROOIJ, H. C. J, DE BOTH, N. J, BENNER, R

“…Delayed-type hypersensitivity (DTH) to Rauscher murine leukaemia virus (R-MuLV) encoded or induced determinants was induced in mice by three syngeneic…”
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Structure and function of the androgen receptor by Brinkmann, A O, Klaasen, P, Kuiper, G G, van der Korput, J A, Bolt, J, de Boer, W, Smit, A, Faber, P W, van Rooij, H C, Geurts van Kessel, A

“…The androgen receptor in several species (human, rat, calf) is a monomeric protein with a molecular mass of 100-110 kDa. The steroid binding domain is confined…”
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