Search Results - "van Rijt, Leonie S"

Immunotoxicity of organophosphate flame retardants TPHP and TDCIPP on murine dendritic cells in vitro by Canbaz, Derya, Logiantara, Adrian, van Ree, Ronald, van Rijt, Leonie S.

“…Organophosphate flame retardants (PFRs) are commonly used as alternatives for the banned polybrominated diphenyl ethers (PBDEs) and are ubiquitously detected…”
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Dendritic cells are crucial for maintenance of tertiary lymphoid structures in the lung of influenza virus-infected mice by GeurtsvanKessel, Corine H, Willart, Monique A M, Bergen, Ingrid M, van Rijt, Leonie S, Muskens, Femke, Elewaut, Dirk, Osterhaus, Albert D M E, Hendriks, Rudi, Rimmelzwaan, Guus F, Lambrecht, Bart N

“…Tertiary lymphoid organs (TLOs) are organized aggregates of B and T cells formed in postembryonic life in response to chronic immune responses to infectious…”
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In vivo depletion of lung CD11c+ dendritic cells during allergen challenge abrogates the characteristic features of asthma by van Rijt, Leonie S, Jung, Steffen, Kleinjan, Alex, Vos, Nanda, Willart, Monique, Duez, Catherine, Hoogsteden, Henk C, Lambrecht, Bart N

“…Although dendritic cells (DCs) play an important role in sensitization to inhaled allergens, their function in ongoing T helper (Th)2 cell-mediated…”
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Persistent Activation of Dendritic Cells after Resolution of Allergic Airway Inflammation Breaks Tolerance to Inhaled Allergens in Mice by VAN RIJT, Leonie S, VOS, Nanda, WILLART, Monique, MUSKENS, Femke, TAK, Paul P, VAN DER HORST, Corine, HOOGSTEDEN, Henk C, LAMBRECHT, Bart N

“…Polysensitization of patients who are allergic is a common feature. The underlying immunologic mechanism is not clear. The maturation status of dendritic cells…”
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A rapid flow cytometric method for determining the cellular composition of bronchoalveolar lavage fluid cells in mouse models of asthma by van Rijt, Leonie S, Kuipers, Harmjan, Vos, Nanda, Hijdra, Daniëlle, Hoogsteden, Henk C, Lambrecht, Bart N

“…Mouse models of allergic asthma are increasingly used to study the immunopathology of this complex disorder. The degree and type of airway inflammation is…”
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Sustained desensitization to bacterial Toll-like receptor ligands after resolution of respiratory influenza infection by Didierlaurent, Arnaud, Goulding, John, Patel, Seema, Snelgrove, Robert, Low, Lionel, Bebien, Magali, Lawrence, Toby, van Rijt, Leonie S, Lambrecht, Bart N, Sirard, Jean-Claude, Hussell, Tracy

“…The World Health Organization estimates that lower respiratory tract infections (excluding tuberculosis) account for approximately 35% of all deaths caused by…”
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Clearance of influenza virus from the lung depends on migratory langerin+CD11b- but not plasmacytoid dendritic cells by GeurtsvanKessel, Corine H, Willart, Monique A M, van Rijt, Leonie S, Muskens, Femke, Kool, Mirjam, Baas, Chantal, Thielemans, Kris, Bennett, Clare, Clausen, Björn E, Hoogsteden, Henk C, Osterhaus, Albert D M E, Rimmelzwaan, Guus F, Lambrecht, Bart N

“…Although dendritic cells (DCs) play an important role in mediating protection against influenza virus, the precise role of lung DC subsets, such as CD11b- and…”
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Oxidative Stress: Promoter of Allergic Sensitization to Protease Allergens? by van Rijt, Leonie S, Utsch, Lara, Lutter, René, van Ree, Ronald

“…Allergies arise from aberrant T helper type 2 responses to allergens. Several respiratory allergens possess proteolytic activity, which has been recognized to…”
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Birch pollen‐specific subcutaneous immunotherapy reduces ILC2 frequency but does not suppress IL‐33 in mice by Rijt, Leonie S., Logiantara, Adrian, Canbaz, Derya, Ree, Ronald

“…Background The underlying mechanism of allergen‐specific subcutaneous immunotherapy (SCIT) is not yet fully understood, but suppression of allergen‐specific…”
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Nuclear Receptor Nur77 Attenuates Airway Inflammation in Mice by Suppressing NF-κB Activity in Lung Epithelial Cells by Kurakula, Kondababu, Vos, Mariska, Logiantara, Adrian, Roelofs, Joris J, Nieuwenhuis, Maartje A, Koppelman, Gerard H, Postma, Dirkje S, van Rijt, Leonie S, de Vries, Carlie J M

“…Allergic asthma is characterized by persistent chronic airway inflammation, which leads to mucus hypersecretion and airway hyperresponsiveness. Nuclear…”
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Indoor Pollutant Hexabromocyclododecane Has a Modest Immunomodulatory Effect on House Dust Mite Induced Allergic Asthma in Mice by Canbaz, Derya, Logiantara, Adrian, Hamers, Timo, van Ree, Ronald, van Rijt, Leonie S

“…Hexabromocyclododecane (HBCD) has been recognized as an indoor pollutant. HBCD is added as a flame retardant to many consumer products and leaches from the…”
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Respiratory viral infections and asthma pathogenesis: A critical role for dendritic cells? by van Rijt, Leonie S., Kessel, Corine H. Geurts van, Boogaard, Ivette, Lambrecht, Bart N.

“…Respiratory viral infections can influence the course of asthma at different time points. Severe respiratory viral infections during early age are associated…”
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An essential role for dendritic cells in human and experimental allergic rhinitis by KleinJan, Alex, Willart, Monique, van Rijt, Leonie S., Braunstahl, Gert-Jan, Leman, Karolina, Jung, Steffen, Hoogsteden, Henk C., Lambrecht, Bart N.

“…In allergic rhinitis (AR) CD4 + T H2 lymphocytes control inflammation by secreting T H2 cytokines, but little is known about how these cells are activated to…”
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Indoor pollutant hexabromocyclododecane enhances house dust mite-induced activation of human monocyte-derived dendritic cells by Canbaz, Derya, Lebre, M Cristina, Logiantara, Adrian, van Ree, Ronald, van Rijt, Leonie S

“…The indoor pollutant hexabromocyclododecane (HBCD) has been added as flame retardant to many consumer products but detaches and accumulates in house dust…”
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Birch pollen immunotherapy in mice: inhibition of Th2 inflammation is not sufficient to decrease airway hyper-reactivity by van Rijt, Leonie S, Gouveia, Lara, Logiantara, Adrian, Canbaz, Derya, Opstelten, Dirk-Jan, van der Kleij, Hanneke P M, van Ree, Ronald

“…Suppression of Th2 cytokine production by allergen-specific Th2 cells is considered to be critical for the suppression of allergic symptoms by subcutaneous…”
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Essential role of dendritic cell CD80/CD86 costimulation in the induction, but not reactivation, of TH2 effector responses in a mouse model of asthma by van Rijt, Leonie S, Vos, Nanda, Willart, Monique, KleinJan, Alex, Coyle, Anthony J, Hoogsteden, Henk C, Lambrecht, Bart N

“…Airway dendritic cells (DCs) are crucial for the generation of TH2 cells from naive T cells during sensitization and for reactivation of primed TH2 cells on…”
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Respiratory syncytial virus differentially activates murine myeloid and plasmacytoid dendritic cells by Boogaard, Ivette, van Oosten, Marijke, van Rijt, Leonie S, Muskens, Femke, Kimman, Tjeerd G, Lambrecht, Bart N, Buisman, Anne-Marie

“…Respiratory syncytial virus (RSV) is the primary cause of bronchiolitis in young children. Upon infection both T helper 1 (Th1) and Th2 cytokines are produced…”
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T‐cell regulation of neutrophil infiltrate at the early stages of a murine colitis model by van Lierop, Pieter P.E., de Haar, Colin, Lindenbergh‐Kortleve, Dicky J., Simons‐Oosterhuis, Ytje, van Rijt, Leonie S., Lambrecht, Bart N., Escher, Johanna C., Samsom, Janneke N., Nieuwenhuis, Edward E.S.

“…Background: T‐cells are a main target for antiinflammatory drugs in inflammatory bowel disease. As the innate immune system is also implicated in the…”
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Airway Eosinophils Accumulate in the Mediastinal Lymph Nodes but Lack Antigen-Presenting Potential for Naive T Cells by van Rijt, Leonie S, Vos, Nanda, Hijdra, Danielle, de Vries, Victor C, Hoogsteden, Henk C, Lambrecht, Bart N

“…Asthma is characterized by infiltration of the airway wall with eosinophils. Although eosinophils are considered to be effector cells, recent studies have…”
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S1727 DC Subtypes in the Colon and Their Role in TNBS Colitis by de Haar, Colin, van Lierop, Pieter, Lindenbergh-Kortleve, Dicky, Kool, Mirjam, van Rijt, Leonie S, Lambrecht, Bart, Nieuwenhuis, Edward, Samsom, Janneke

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