Search Results - "van Rijnsbergen, Peter"

Strategic and Tactical Approaches to the Synthesis of 5,6-Dihydro-[1,2,4]oxadiazines by J. N. Veerman, Johan, G. Bursavich, Matthew, B. Bruseker, Yorik, C. J. van Esseveldt, Bart, Glen, Rebecca, A. Harrison, Bryce, H. Heijne, Erik, J. McRiner, Andrew, M. Meulemans, Tommi, van Rijnsbergen, Peter, Zonneveld, Wim, A. Burnett, Duane

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Discovery of 2,4-1 H -Imidazole Carboxamides as Potent and Selective TAK1 Inhibitors by Veerman, Johan J N, Bruseker, Yorik B, Damen, Eddy, Heijne, Erik H, van Bruggen, Wendy, Hekking, Koen F W, Winkel, Rob, Hupp, Christopher D, Keefe, Anthony D, Liu, Julie, Thomson, Heather A, Zhang, Ying, Cuozzo, John W, McRiner, Andrew J, Mulvihill, Mark J, van Rijnsbergen, Peter, Zech, Birgit, Renzetti, Louis M, Babiss, Lee, Müller, Gerhard

“…Herein we report the discovery of 2,4-1 -imidazole carboxamides as novel, biochemically potent, and kinome selective inhibitors of transforming growth factor…”
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Discovery of 2,4‑1H‑Imidazole Carboxamides as Potent and Selective TAK1 Inhibitors by Veerman, Johan J. N, Bruseker, Yorik B, Damen, Eddy, Heijne, Erik H, van Bruggen, Wendy, Hekking, Koen F. W, Winkel, Rob, Hupp, Christopher D, Keefe, Anthony D, Liu, Julie, Thomson, Heather A, Zhang, Ying, Cuozzo, John W, McRiner, Andrew J, Mulvihill, Mark J, van Rijnsbergen, Peter, Zech, Birgit, Renzetti, Louis M, Babiss, Lee, Müller, Gerhard

“…Herein we report the discovery of 2,4-1H-imidazole carboxamides as novel, biochemically potent, and kinome selective inhibitors of transforming growth factor…”
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Trifluoromethylphenyl as P2 for ketoamide-based cathepsin S inhibitors by Cai, Jiaqiang, Robinson, John, Belshaw, Simone, Everett, Kathryn, Fradera, Xavier, van Zeeland, Mario, van Berkom, Leon, van Rijnsbergen, Peter, Popplestone, Lucy, Baugh, Mark, Dempster, Maureen, Bruin, John, Hamilton, William, Kinghorn, Emma, Westwood, Paul, Kerr, Jennifer, Rankovic, Zoran, Arbuckle, Wullie, Bennett, D. Jonathan, Jones, Philip S., Long, Clive, Martin, Iain, Uitdehaag, Joost C.M., Meulemans, Tommi

“…By using a small atom (Cl, F, or Me) to increase the torsion angle between the phenyl ring and the attached secondary amide, trifluoromethylphenyl motif was…”
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