Search Results - "van Rijn, Piet"

Novel Function of Bluetongue Virus NS3 Protein in Regulation of the MAPK/ERK Signaling Pathway by Kundlacz, Cindy, Pourcelot, Marie, Fablet, Aurore, Amaral Da Silva Moraes, Rayane, Léger, Thibaut, Morlet, Bastien, Viarouge, Cyril, Sailleau, Corinne, Turpaud, Mathilde, Gorlier, Axel, Breard, Emmanuel, Lecollinet, Sylvie, van Rijn, Piet A, Zientara, Stephan, Vitour, Damien, Caignard, Grégory

“…Bluetongue virus (BTV) is an arbovirus transmitted by blood-feeding midges to a wide range of wild and domestic ruminants. In this report, we showed that BTV,…”
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"Frozen evolution" of an RNA virus suggests accidental release as a potential cause of arbovirus re-emergence by Pascall, David J, Nomikou, Kyriaki, Bréard, Emmanuel, Zientara, Stephan, Filipe, Ana da Silva, Hoffmann, Bernd, Jacquot, Maude, Singer, Joshua B, De Clercq, Kris, Bøtner, Anette, Sailleau, Corinne, Viarouge, Cyril, Batten, Carrie, Puggioni, Giantonella, Ligios, Ciriaco, Savini, Giovanni, van Rijn, Piet A, Mertens, Peter P C, Biek, Roman, Palmarini, Massimo

“…The mechanisms underlying virus emergence are rarely well understood, making the appearance of outbreaks largely unpredictable. Bluetongue virus serotype 8…”
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Full Genome Characterisation of Bluetongue Virus Serotype 6 from the Netherlands 2008 and Comparison to Other Field and Vaccine Strains by Maan, Sushila, Maan, Narender S, Rijn, Piet A. van, Gennip, René G.P. van, Sanders, Anna, Wright, Isabel M, Batten, Carrie, Hoffmann, Bernd, Eschbaumer, Michael, Oura, Chris A.L, Potgieter, Abraham C, Nomikou, Kyriaki, Mertens, Peter P.C

“…In mid September 2008, clinical signs of bluetongue (particularly coronitis) were observed in cows on three different farms in eastern Netherlands (Luttenberg,…”
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Prospects of Next-Generation Vaccines for Bluetongue by van Rijn, Piet A

“…Bluetongue (BT) is a haemorrhagic disease of wild and domestic ruminants with a huge economic worldwide impact on livestock. The disease is caused by BT-virus…”
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Bluetongue virus nonstructural protein NS3/NS3a is not essential for virus replication by van Gennip, René G P, van de Water, Sandra G P, van Rijn, Piet A

“…Orbiviruses form the largest genus of the family Reoviridae consisting of at least 23 different virus species. One of these is the bluetongue virus (BTV) and…”
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Virus and host factors affecting the clinical outcome of bluetongue virus infection by Caporale, Marco, Di Gialleonorado, Luigina, Janowicz, Anna, Wilkie, Gavin, Shaw, Andrew, Savini, Giovanni, Van Rijn, Piet A, Mertens, Peter, Di Ventura, Mauro, Palmarini, Massimo

“…Bluetongue is a major infectious disease of ruminants caused by bluetongue virus (BTV), an arbovirus transmitted by Culicoides. Here, we assessed virus and…”
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Diagnostic DIVA tests accompanying the Disabled Infectious Single Animal (DISA) vaccine platform for African horse sickness by van Rijn, Piet A., Maris-Veldhuis, Mieke A., Boonstra, Jan, van Gennip, René G.P.

“…•The 77aa region of AHSV NS3/NS3a encompassing the Late Domain is immunogenic.•DIVA PCR testing compatible with the AHS DISA vaccine platforms.•DIVA ELISA…”
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Emergence of Bluetongue Virus Serotype 3, the Netherlands, September 2023 by Holwerda, Melle, Santman-Berends, Inge M G A, Harders, Frank, Engelsma, Marc, Vloet, Rianka P M, Dijkstra, Eveline, van Gennip, Rene G P, Mars, Maria H, Spierenburg, Marcel, Roos, Lotte, van den Brom, René, van Rijn, Piet A

“…Since 1998, notifiable bluetongue virus (BTV) serotypes 1-4, 6, 8, 9, 11, and 16 have been reported in Europe. In August 2006, a bluetongue (BT) outbreak…”
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African horse sickness virus (AHSV) with a deletion of 77 amino acids in NS3/NS3a protein is not virulent and a safe promising AHS Disabled Infectious Single Animal (DISA) vaccine platform by van Rijn, Piet A., Maris-Veldhuis, Mieke A., Potgieter, Christiaan A., van Gennip, René G.P.

“…•Rescue of high virulent AHSV by reverse genetics.•In-frame deletion of 77 codons in genome segment 10 is crucial for virulence.•Safety and protection by AHS…”
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One after the other: A novel Bluetongue virus strain related to Toggenburg virus detected in the Piedmont region (North‐western Italy), extends the panel of novel atypical BTV strains by Marcacci, Maurilia, Sant, Serena, Mangone, Iolanda, Goria, Maria, Dondo, Alessandro, Zoppi, Simona, van Gennip, René G. P., Radaelli, Maria Cristina, Cammà, Cesare, van Rijn, Piet A., Savini, Giovanni, Lorusso, Alessio

“…In this rapid communication, a novel atypical bluetongue virus (BTV) strain detected in goats in the Piedmont region (north‐western Italy) is described. This…”
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Bluetongue viruses based on modified-live vaccine serotype 6 with exchanged outer shell proteins confer full protection in sheep against virulent BTV8 by van Gennip, René G P, van de Water, Sandra G P, Maris-Veldhuis, Mieke, van Rijn, Piet A

“…Since 1998, Bluetongue virus (BTV)-serotypes 1, 2, 4, 9, and 16 have invaded European countries around the Mediterranean Basin. In 2006, a huge BT outbreak…”
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Rescue of recent virulent and avirulent field strains of bluetongue virus by reverse genetics by van Gennip, René G P, van de Water, Sandra G P, Potgieter, Christiaan A, Wright, Isabel M, Veldman, Daniel, van Rijn, Piet A

“…Since 1998, Bluetongue virus (BTV)-serotypes 1, 2, 4, 9, and 16 have invaded European countries around the Mediterranean Basin. In 2006, a huge BT-outbreak…”
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RNA elements in open reading frames of the bluetongue virus genome are essential for virus replication by Feenstra, Femke, van Gennip, René G P, van de Water, Sandra G P, van Rijn, Piet A

“…Members of the Reoviridae family are non-enveloped multi-layered viruses with a double stranded RNA genome consisting of 9 to 12 genome segments. Bluetongue…”
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Spatial Transmission Characteristics of the Bluetongue Virus Serotype 3 Epidemic in The Netherlands, 2023 by Boender, Gert-Jan, Hagenaars, Thomas J, Holwerda, Melle, Spierenburg, Marcel A H, van Rijn, Piet A, van der Spek, Arco N, Elbers, Armin R W

“…A devastating bluetongue (BT) epidemic caused by bluetongue virus serotype 3 (BTV-3) has spread throughout most of the Netherlands within two months since the…”
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Requirements and comparative analysis of reverse genetics for bluetongue virus (BTV) and African horse sickness virus (AHSV) by van Rijn, Piet A, van de Water, Sandra G P, Feenstra, Femke, van Gennip, René G P

“…Bluetongue virus (BTV) and African horse sickness virus (AHSV) are distinct arthropod borne virus species in the genus Orbivirus (Reoviridae family), causing…”
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Prevalence and predictors of vector-borne pathogens in Dutch roe deer by Wijburg, Sara R, Fonville, Manoj, de Bruin, Arnout, van Rijn, Piet A, Montizaan, Margriet G E, van den Broek, Jan, Sprong, Hein, Rijks, Jolianne M

“…The main objective of this study was to determine the prevalence of nine vector-borne pathogens or pathogen genera in roe deer (Capreolus capreolus) in the…”
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The Bluetongue Disabled Infectious Single Animal (DISA) Vaccine Platform Based on Deletion NS3/NS3a Protein Is Safe and Protective in Cattle and Enables DIVA by van Rijn, Piet A., Maris-Veldhuis, Mieke A., van Gennip, René G. P.

“…The bluetongue virus (BTV) is transmitted by Culicoides biting midges and causes bluetongue (BT), an OIE-notifiable disease of ruminants. At least 29 BTV…”
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Rapid Generation of Replication-Deficient Monovalent and Multivalent Vaccines for Bluetongue Virus: Protection against Virulent Virus Challenge in Cattle and Sheep by Celma, Cristina C P, Boyce, Mark, van Rijn, Piet A, Eschbaumer, Michael, Wernike, Kerstin, Hoffmann, Bernd, Beer, Martin, Haegeman, Andy, De Clercq, Kris, Roy, Polly

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Vector competence is strongly affected by a small deletion or point mutations in bluetongue virus by van Gennip, René G P, Drolet, Barbara S, Rozo Lopez, Paula, Roost, Ashley J C, Boonstra, Jan, van Rijn, Piet A

“…Transmission of vector-borne virus by insects is a complex mechanism consisting of many different processes; viremia in the host, uptake, infection and…”
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Engineering recombinant replication-competent bluetongue viruses expressing reporter genes for in vitro and non-invasive in vivo studies by Utrilla-Trigo, Sergio, Jiménez-Cabello, Luis, Marín-López, Alejandro, Illescas-Amo, Miguel, Andrés, Germán, Calvo-Pinilla, Eva, Lorenzo, Gema, van Rijn, Piet A, Ortego, Javier, Nogales, Aitor

“…Bluetongue virus (BTV) is the causative agent of the important livestock disease bluetongue (BT), which is transmitted via Culicoides bites. BT causes severe…”
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