Search Results - "van Rensburg, Walter J. Janse"
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Prevalence of primary HIV-associated thrombocytopenia in a central South African population
Published in South African medical journal (01-09-2022)“…To the Editor: Haematological abnormalities are common manifestations in HIV-positive individuals. Thrombocytopenia (platelet count…”
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Molecular suitability of the chacma baboon in human‐targeted Von Willebrand factor directed studies
Published in Journal of medical primatology (01-06-2019)“…Background Von Willebrand factor (VWF) has a central role in primary haemostasis and is a popular pharmaceutical target in the prevention and treatment of…”
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3
HLA major allele group frequencies in a diverse population of the Free State Province, South Africa
Published in Heliyon (01-04-2021)“…Human Leucocyte Antigens (HLA) play a vital role in disease pathogenesis and transplant rejection. HLA-typing is a useful tool in predicting disease…”
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Post-mortem evidence of a diverse distribution pattern of atherosclerosis in the South African population
Published in Scientific reports (05-07-2022)“…Cardiovascular diseases (CVDs) are the number one cause of mortality worldwide. The disease profile of CVD varies considerably between different demographic…”
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Forensic autopsy-confirmed thrombosis-related deaths: the danger in the bones
Published in Journal of thrombosis and thrombolysis (01-10-2022)“…Thrombosis is a potentially life-threatening condition related to roughly a quarter of all deaths globally. Many of these deaths occur inside healthcare…”
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Genetic variant detection in a South African haemophilia B population
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-05-2024)“…Haemophilia B is characterised by a deficiency of factor IX (FIX) protein due to genetic variants in the FIX gene (F9). Genetic testing may have a vital role…”
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HLA and disease : missing clinical data on laboratory request forms – a missed opportunity
Published in South African medical journal (01-01-2021)“…To the Editor: HLA typing is one of the most vital tools in the pre-transplantation work-up process.[1] However, not only is HLA typing vital in identifying…”
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Lifestyle Change Alone Sufficient to Lower Cholesterol in Male Patient With Moderately Elevated Cholesterol: A Case Report
Published in American journal of lifestyle medicine (01-03-2019)“…Background. Cardiovascular disease is a major cause of deaths. Elevated cholesterol levels to above the normal reference range is a major risk factor for…”
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Comparison of common platelet receptors between the chacma baboon (Papio ursinus) and human for use in pre-clinical human-targeted anti-platelet studies
Published in Platelets (Edinburgh) (18-05-2016)“…Anti-platelet agents play a central part in the treatment and prevention of acute thrombotic events. Discriminating animal models are needed for the…”
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Rapid identification of the intron 22 inversion in haemophilia A
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-01-2017)Get full text
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Comparison of Commercially Available Blood Collection Tubes Containing Sodium Citrate and Hirudin in Platelet Aggregation Testing
Published in Medical science monitor. Basic research (27-07-2017)“…BACKGROUND Platelet reactivity assessment is an important tool in both the causal determination of bleeding diathesis as well as in the evaluation of the…”
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The Cape Chacma baboon is not suitable for evaluating human targeted anti-GPVI agents
Published in Platelets (Edinburgh) (18-08-2015)“…An effective and safe anti-platelet drug is central to the management of patients with acute coronary syndrome (ACS). Glycoprotein VI (GPVI) is currently…”
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Tirofiban versus abciximab: tirofiban is administered at suboptimal dosages when evaluated in an arterial thrombosis model in non-human primates
Published in Clinical and experimental medicine (01-12-2012)“…To prevent thrombosis in high-risk acute coronary syndrome patients undergoing percutaneous coronary intervention for re-vascularisation, concomitant…”
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Polyunsaturated fatty acids cause apoptosis in C. albicans and C. dubliniensis biofilms
Published in Biochimica et biophysica acta (01-10-2012)“…Polyunsaturated fatty acids (PUFAs) have antifungal properties, but the mode by which they induce their action is not always clear. The aim of the study was to…”
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