Search Results - "van Rensburg, D. Janse"
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Preliminary Screening of South African Plants for Binding Affinity to the Serotonin Reuptake Transporter and Adenosine A1/A2A Receptors
Published in Scientia pharmaceutica (01-01-2023)“…In South African traditional medicine, Gomphocarpus fruticosus (L.) W.T. Aiton, Hypoxis hemerocallidea Fisch. & C.A. Mey., and Leonotis leonurus. (L.) R.Br…”
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2
On the basis of sex: male vs. female rat adenosine A1/A2A receptor affinity
Published in BMC research notes (10-08-2023)“…Abstract Objective To ensure reproducibility in biomedical research, the biological variable sex must be reported; yet a reason for using male (instead of…”
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3
In Vitro and In Vivo Trypanocidal Efficacy of Nitrofuryl- and Nitrothienylazines
Published in ACS omega (14-11-2023)“…African trypanosomiasis is a vector-borne disease of animals and humans in the tsetse fly belt of Africa. Trypanosoma congolense (“nagana”) is the most…”
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4
Design, synthesis and evaluation of amino-3,5-dicyanopyridines and thieno[2,3-b]pyridines as ligands of adenosine A1 receptors for the potential treatment of epilepsy
Published in Medicinal chemistry research (2022)“…Due to the implication of adenosine in seizure suppression, adenosine-based therapies such as adenosine receptor (AR) agonists have been investigated. This…”
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5
In vitro trypanocidal potency and in vivo treatment efficacy of oligomeric ethylene glycol-tethered nitrofurantoin derivatives
Published in European journal of pharmaceutical sciences (01-01-2024)“…•T. congolense trypomastigotes were most susceptible to oligomeric ethylene glycol-tethered nitrofurantoin derivatives.•Arylated derivatives showed the best…”
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Impact of herbivory by Zerenopsis lepida (Lepidoptera: Geometridae) on the endangered Encephalartos eugene-maraisii under field conditions
Published in Biodiversity and conservation (01-06-2023)“…Encephalartos eugene-maraisii is an endangered, endemic plant in the Waterberg Mountain range of South Africa. This is the first report of herbivory by…”
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Exploration of ethylene glycol linked nitrofurantoin derivatives against Leishmania: Synthesis and in vitro activity
Published in Archiv der Pharmazie (Weinheim) (01-05-2023)“…Leishmaniasis is a neglected tropical disease that is caused by the Leishmania parasite. It is estimated that there are more than 350 million people at risk of…”
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Synthesis and in vitro antileishmanial activity of alkylene-linked nitrofurantoin-triazole hybrids
Published in European journal of medicinal chemistry (15-01-2023)“…Leishmaniasis is a vector-borne parasitic disease that mostly affects populations in tropical and sub-tropical countries. There is currently no protective…”
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9
Design, synthesis, electrochemistry and anti-trypanosomatid hit/lead identification of nitrofuranylazines
Published in RSC medicinal chemistry (18-10-2023)“…Chagas disease and leishmaniasis are vector-borne infectious diseases affecting both humans and animals. These neglected tropical diseases can be fatal if not…”
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Square roots of H-nonnegative matrices
Published in Linear algebra and its applications (15-07-2021)“…Roots of matrices are well-studied. The conditions for their existence are understood: The block sizes of nilpotent Jordan blocks, arranged in pairs, have to…”
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Synthesis and in Vitro Antileishmanial Efficacy of Novel Ethylene Glycol Analogues of Benzothiadiazine-1,1-dioxide
Published in Chemistry & biodiversity (31-10-2024)“…Leishmaniasis is a vector-borne, parasitic disease affecting millions of people and animals worldwide. Current therapeutic options have proven to be…”
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12
An alternative canonical form for quaternionic H-unitary matrices
Published in Linear algebra and its applications (15-08-2021)“…The field of linear algebra over the quaternions is a research area which is still in development. In this paper we continue our research on canonical forms…”
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13
Why cordylid lizards are black at the south-western tip of Africa
Published in Journal of zoology (1987) (01-08-2009)“…There is a high incidence of melanism among the cordylid lizards of Africa and it was suggested that melanism has a thermoregulatory function in these species…”
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mth roots of H-selfadjoint matrices
Published in Linear algebra and its applications (01-02-2021)“…In this paper necessary and sufficient conditions are given for the existence of an H-selfadjoint mth root of a given H-selfadjoint matrix. A construction is…”
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15
Evaluation of chemical constituents of Rooibos (Aspalathus linearis) and Honeybush (Cyclopia intermedia) as adenosine A1/A2A receptor ligands
Published in Medicinal chemistry research (01-12-2023)“…Rooibos ( Aspalathus linearis ) and Honeybush ( Cyclopia intermedia ) are popular tisanes in South Africa and are of growing interest due to the wide variety…”
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Acute obturator internus muscle strain in a rugby player: a case report
Published in The Journal of sports medicine and physical fitness (01-12-2015)“…A 28-year-old male rugby player presented with severe onset of right hip pain when he fell awkward after a ruck during an international match. A rare case of…”
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The congested International Match Calendar in football: views of 1055 professional male players
Published in BMC sports science, medicine & rehabilitation (29-11-2022)“…Abstract Background The International Match Calendar congestion affects players recovery. The views of a worldwide cohort of professional football players is…”
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18
Haemangiosarcoma of the os penis in a dog : the most common neoplasm of the canine penis
Published in Journal of the South African Veterinary Association (2014)“…A castrated 9-year-old intact male boerboel cross-breed dog was presented with a month-long history of stranguria. On physical examination, a mass was noted at…”
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Robotic Measurement Solutions for Phased Array Calibration and Pattern Testing
Published in 2023 53rd European Microwave Conference (EuMC) (19-09-2023)“…Phased array antennas offer unparalleled adaptability which make them attractive for use in various multibeam applications. While previously limited to use in…”
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Conference Proceeding -
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World netball cardiac screening guidelines
Published in South African journal of sports medicine (2022)“…Sudden cardiac adverse events remain an area of concern in sport. The precise risk for netball athletes is unknown but the annual incidence of sudden cardiac…”
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