Search Results - "van Overveld, Petra G M"
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Bone morphogenetic protein 7 in the development and treatment of bone metastases from breast cancer
Published in Cancer research (Chicago, Ill.) (15-09-2007)“…Bone morphogenetic protein 7 (BMP7) counteracts the physiological epithelial-to-mesenchymal transition (EMT), a process that is indicative of epithelial…”
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2
Testing the position-effect variegation hypothesis for facioscapulohumeral muscular dystrophy by analysis of histone modification and gene expression in subtelomeric 4q
Published in Human molecular genetics (15-11-2003)“…Facioscapulohumeral muscular dystrophy (FSHD) is a unique dominant disorder involving shortening of an array of tandem 3.3 kb repeats. This copy-number…”
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3
Variable hypomethylation of D4Z4 in facioscapulohumeral muscular dystrophy
Published in Annals of neurology (01-10-2005)“…Facioscapulohumeral muscular dystrophy (FSHD) progressively affects the facial, shoulder, and upper arm muscles and is associated with contractions of the…”
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Hypomethylation of D4Z4 in 4q-linked and non-4q-linked facioscapulohumeral muscular dystrophy
Published in Nature genetics (01-12-2003)“…The autosomal dominant myopathy facioscapulohumeral muscular dystrophy (FSHD1, OMIM 158900) is caused by contraction of the D4Z4 repeat array on 4qter. We show…”
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Advances in optical imaging and novel model systems for cancer metastasis research
Published in Clinical & experimental metastasis (01-11-2007)“…Research into the genetic and physiological interactions of tumours with their host environment requires in vivo assays to address molecular expression…”
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Mechanism and Timing of Mitotic Rearrangements in the Subtelomeric D4Z4 Repeat Involved in Facioscapulohumeral Muscular Dystrophy
Published in American journal of human genetics (01-07-2004)“…Autosomal dominant facioscapulohumeral muscular dystrophy (FSHD1A) is associated with contractions of the polymorphic D4Z4 repeat on chromosome 4qter. Almost…”
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TGF-beta and BMP7 interactions in tumour progression and bone metastasis
Published in Clinical & experimental metastasis (01-11-2007)“…The skeleton is the second most frequent site of metastasis. However, only a restricted number of solid cancers, especially those of the breast and prostate,…”
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BMP7, a Putative Regulator of Epithelial Homeostasis in the Human Prostate, Is a Potent Inhibitor of Prostate Cancer Bone Metastasis in Vivo
Published in The American journal of pathology (01-09-2007)“…Bone morphogenic protein 7 (BMP7) counteracts physiological epithelial-to-mesenchymal transition, a process that is indicative of epithelial plasticity…”
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De Novo Facioscapulohumeral Muscular Dystrophy: Frequent Somatic Mosaicism, Sex-Dependent Phenotype, and the Role of Mitotic Transchromosomal Repeat Interaction between Chromosomes 4 and 10
Published in American journal of human genetics (01-01-2000)“…Autosomal dominant facioscapulohumeral muscular dystrophy (FSHD) is caused by deletion of most copies of the 3.3-kb subtelomeric D4Z4 repeat array on…”
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10
Interchromosomal repeat array interactions between chromosomes 4 and 10: a model for subtelomeric plasticity
Published in Human molecular genetics (22-11-2000)“…Chromosomal rearrangements occur more frequently in subtelomeric domains than in other regions of the genome and are often associated with human pathology. To…”
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11
TGF-[beta] and BMP7 interactions in tumour progression and bone metastasis
Published in Clinical & experimental metastasis (20-11-2007)“…The skeleton is the second most frequent site of metastasis. However, only a restricted number of solid cancers, especially those of the breast and prostate,…”
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Journal Article