Search Results - "van Os, Carel"

Aquaporin 2 Mutations in Nephrogenic Diabetes Insipidus by Loonen, Anne J.M., MSc, Knoers, Nine V.A.M., MD, PhD, van Os, Carel H., PhD, Deen, Peter M.T., PhD

“…Summary Water reabsorption in the renal collecting duct is regulated by the antidiuretic hormone vasopressin (AVP). When the vasopressin V2 receptor, present…”
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Reversed Polarized Delivery of an Aquaporin-2 Mutant Causes Dominant Nephrogenic Diabetes Insipidus by Kamsteeg, Erik-Jan, Bichet, Daniel G., Irene B. M. Konings, Nivet, Hubert, Lonergan, Michelle, Arthus, Marie-Françoise, van Os, Carel H., Peter M. T. Deen

“…Vasopressin regulates body water conservation by redistributing aquaporin-2 (AQP2) water channels from intracellular vesicles to the apical surface of renal…”
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Calcitriol controls the epithelial calcium channel in kidney by HOENDEROP, Joost G. J, MÜLLER, Dominik, BINDELS, René J. M, VAN DER KEMP, Annemiete W. C. M, HARTOG, Anita, SUZUKI, Makoto, ISHIBASHI, Kenichi, IMAI, Masashi, SWEEP, Fred, WILLEMS, Peter H. G. M, VAN OS, Carel H

“…The recently cloned epithelial Ca2+ channel (ECaC), which is expressed primarily in 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3))-responsive Ca2+ -transporting…”
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Requirement of Human Renal Water Channel Aquaporin-2 for Vasopressin-Dependent Concentration of Urine by Peter M. T. Deen, Marian A. J. Verdijk, Nine V. A. M. Knoers, Wieringa, Bé, Leo A. H. Monnens, van Os, Carel H., van Oost, Bernard A.

“…Concentration of urine in mammals is regulated by the antidiuretic hormone vasopressin. Binding of vasopressin to its V2 receptor leads to the insertion of…”
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The epithelial sodium channel (ENaC) is intracellularly located as a tetramer by Dijkink, Lisette, Hartog, Anita, van Os, Carel H, Bindels, René J M

“…The epithelial sodium channel (ENaC) plays an important role in Na(+) homeostasis by determining the Na(+) transport rate in so-called end-organs such as the…”
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Heteroligomerization of an Aquaporin-2 mutant with wild-type Aquaporin-2 and their misrouting to late endosomes/lysosomes explains dominant nephrogenic diabetes insipidus by Marr, Nannette, Bichet, Daniel G, Lonergan, Michele, Arthus, Marie-Francoise, Jeck, Nikola, Seyberth, Hannsjörg W., Rosenthal, Walter, van Os, Carel H., Oksche, Alexander, Deen, Peter M. T.

“…Autosomal nephrogenic diabetes insipidus (NDI), a disease in which the kidney is unable to concentrate urine in response to vasopressin, is caused by mutations…”
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An impaired routing of wild-type aquaporin-2 after tetramerization with an aquaporin-2 mutant explains dominant nephrogenic diabetes insipidus by Kamsteeg, Erik-Jan, Wormhoudt, Thera A.M., Rijss, Johan P.L., van Os, Carel H., Deen, Peter M.T.

“…Autosomal recessive and dominant nephrogenic diabetes insipidus (NDI), a disease in which the kidney is unable to concentrate urine in response to vasopressin,…”
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Epithelial aquaporins by Deen, Peter MT, van Os, Carel H

“…The past year has brought significant advances in our understanding of the involvement of aquaporins in the regulation of water balance. Besides the…”
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Multidrug resistance protein mrp2 mediates ATP-dependent transport of classic renal organic anion p-aminohippurate by Van Aubel, R A, Peters, J G, Masereeuw, R, Van Os, C H, Russel, F G

“…p-Aminohippurate (PAH) is widely used as a model substrate to characterize organic anion transport in kidney proximal tubules. The carrier responsible for…”
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Thiazide-induced hypocalciuria is accompanied by a decreased expression of Ca2+ transport proteins in kidney by Nijenhuis, Tom, Hoenderop, Joost G.J., Loffing, Johannes, van der Kemp, Annemiete W.C.M., van Os, Carel H., Bindels, René J.M.

“…Thiazide-induced hypocalciuria is accompanied by a decreased expression of Ca2+ transport proteins in kidney. Thiazide diuretics have the unique characteristic…”
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Expression and immunolocalization of multidrug resistance protein 2 in rabbit small intestine by Van Aubel, Rémon A.M.H, Hartog, Anita, Bindels, René J.M, Van Os, Carel H, Russel, Frans G.M

“…Multidrug resistance protein 2 (MRP2) is an ATP-dependent transporter of anionic drugs and conjugates. It functions as an efflux pump in the apical membranes…”
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Physiological relevance of aquaporins: luxury or necessity? by van Os, Carel H., Kamsteeg, Erik-Jan, Marr, Nannette, Deen, Peter M.T.

“…Aquaporins are members of a large family of pore-forming intrinsic membrane proteins, the MIP family. Based on their permeability properties they are now…”
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Epithelial Ca(2+) channel (ECAC1) in autosomal dominant idiopathic hypercalciuria by Müller, Dominik, Hoenderop, Joost G J, Vennekens, Rudi, Eggert, Paul, Harangi, Ferenc, Méhes, Károly, Garcia-Nieto, Victor, Claverie-Martin, Felix, Os, Carel H van, Nilius, Bernd, J M Bindels, René

“…The epithelial Ca(2+) channel (ECaC) exhibits the defining properties for being the gatekeeper in 1,25-dihydroxyvitamin D(3)-regulated Ca(2+) (re)absorption…”
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Cell-biologic and functional analyses of five new Aquaporin-2 missense mutations that cause recessive nephrogenic diabetes insipidus by MARR, Nannette, BICHET, Daniel G, KNOERS, Nine V. A. M, LANDAU, Daniel, BALFE, William J, OKSCHE, Alexander, ROSENTHAL, Walter, MÜLLER, Dominik, VAN OS, Carel H, DEEN, Peter M. T, HOEFS, Susan, SAVELKOUL, Paul J. M, KONINGS, Irene B. M, DE MATTIA, Fabrizio, GRAAT, Michael P. J, ARTHUS, Marie-Francoise, LONERGAN, Michele, FUJIWARA, T. Mary

“…Mutations in the Aquaporin-2 gene, which encodes a renal water channel, have been shown to cause autosomal nephrogenic diabetes insipidus (NDI), a disease in…”
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The Epithelial Calcium Channel, ECaC, Is Activated by Hyperpolarization and Regulated by Cytosolic Calcium by Hoenderop, Joost G.J., van der Kemp, Annemiete W.C.M., Hartog, Anita, van Os, Carel H., Willems, Peter H.G.M., Bindels, René J.M.

“…The recently cloned epithelial Ca2+ channel, ECaC, which is expressed in the apical membrane of 1,25-dihydroxyvitamin D3-responsible epithelia, was…”
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Epithelial calcium channel: gate-keeper of active calcium reabsorption by Hoenderop, Joost G.J, Müller, Dominik, Suzuki, Makoto, van Os, Carel H, Bindels, René J.M

“…The epithelial calcium channel present in the apical membrane of 1,25-dihydroxyvitamin D3-responsive nephron segments represents the first member of a new…”
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Mechanisms and interaction of vinblastine and reduced glutathione transport in membrane vesicles by the rabbit multidrug resistance protein Mrp2 expressed in insect cells by Van Aubel, R A, Koenderink, J B, Peters, J G, Van Os, C H, Russel, F G

“…The present study examined how the multidrug resistance protein (MRP) 2, which is an ATP-dependent anionic conjugate transporter, also mediates transport of…”
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Adenosine triphosphate-dependent transport of anionic conjugates by the rabbit multidrug resistance-associated protein Mrp2 expressed in insect cells by van Aubel, R A, van Kuijck, M A, Koenderink, J B, Deen, P M, van Os, C H, Russel, F G

“…The multidrug resistance-associated protein Mrp2 is expressed in liver, kidney, and small intestine and mediates ATP-dependent transport of conjugated organic…”
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Time-dependent regulation by aldosterone of the amiloride-sensitive Na+ channel in rabbit kidney by Dijkink, L, Hartog, A, Deen, P M, van Os, C H, Bindels, R J

“…The epithelial Na+ channel (ENaC) functions as the rate-limiting factor in aldosterone-regulated transcellular Na+ transport. In the study described here, the…”
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Modulation of aldosterone-induced stimulation of ENaC synthesis by changing the rate of apical Na+ entry by Dijkink, L, Hartog, A, Van Os, C H, Bindels, R J

“…Primary cultures of immunodissected rabbit connecting tubule and cortical collecting duct cells were used to investigate the effect of apical Na+ entry rate on…”
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