Search Results - "van Oostveen, Wieke"
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Imaging Techniques in Alzheimer's Disease: A Review of Applications in Early Diagnosis and Longitudinal Monitoring
Published in International journal of molecular sciences (20-02-2021)“…Alzheimer's disease (AD) is a progressive neurodegenerative disorder affecting many individuals worldwide with no effective treatment to date. AD is…”
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Label-free high-throughput screening assay for the identification of norepinephrine transporter (NET/SLC6A2) inhibitors
Published in Scientific reports (10-06-2021)“…The human norepinephrine transporter (NET) is an established drug target for a wide range of psychiatric disorders. Conventional methods that are used to…”
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Label-free detection of prostaglandin transporter (SLCO2A1) function and inhibition: insights by wound healing and TRACT assays
Published in Frontiers in pharmacology (09-05-2024)“…The prostaglandin transporter (PGT, SLCO2A1) mediates transport of prostanoids (a.o. prostaglandin E2 (PGE )) into cells and thereby promotes their…”
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Pathogenic role of anti-nuclear autoantibodies in systemic sclerosis: Insights from other rheumatic diseases
Published in Immunological reviews (09-09-2024)“…Systemic sclerosis (SSc) is a severe autoimmune disease characterized by vasculopathy, fibrosis, and dysregulated immunity, with hallmark autoantibodies…”
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Autoantibodies targeting G protein-coupled receptors: An evolving history in autoimmunity. Report of the 4th international symposium
Published in Autoimmunity reviews (01-05-2023)“…G protein-coupled receptors (GPCR) are involved in various physiological and pathophysiological processes. Functional autoantibodies targeting GPCRs have been…”
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