Search Results - "van Oosterhout, M. F. M."
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Short telomere length in IPF lung associates with fibrotic lesions and predicts survival
Published in PloS one (27-12-2017)“…Telomere maintenance dysfunction has been implicated in the pathogenesis of Idiopathic Pulmonary Fibrosis (IPF). However, the mechanism of how telomere length…”
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From organ to cell: Multi-level telomere length assessment in patients with idiopathic pulmonary fibrosis
Published in PloS one (07-01-2020)“…A subset of patients with idiopathic pulmonary fibrosis (IPF) contains short leukocyte telomeres or telomere related mutations. We previously showed that…”
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Surfactant Protein C Mutations Are the Basis of a Significant Portion of Adult Familial Pulmonary Fibrosis in a Dutch Cohort
Published in American journal of respiratory and critical care medicine (01-12-2010)“…Familial clustering of adult idiopathic interstitial pneumonias (IIP) suggests that genetic factors might play an important role in disease development…”
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Asynchronous electrical activation induces asymmetrical hypertrophy of the left ventricular wall
Published in Circulation (New York, N.Y.) (11-08-1998)“…Asynchronous electrical activation, induced by ventricular pacing, causes regional differences in workload, which is lower in early- than in late-activated…”
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Small cell carcinoma of the lung and large cell neuroendocrine carcinoma interobserver variability
Published in Histopathology (01-02-2010)“…den Bakker M A, Willemsen S, Grünberg K, Noorduijn L A, van Oosterhout M F M, van Suylen R J, Timens W, Vrugt B, Wiersma‐van Tilburg A & Thunnissen F B J M…”
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TINF2 Gene Mutation in a Patient with Pulmonary Fibrosis
Published in Case reports in pulmonology (01-01-2016)“…Pulmonary fibrosis is a frequent manifestation of telomere syndromes. Telomere gene mutations are found in up to 25% and 3% of patients with familial disease…”
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Coronary artery bypass grafting in Takayasu's disease--importance of the proximal anastomosis: a case report
Published in Journal of medical case reports (15-12-2015)“…Treatment of coronary artery involvement in Takayasu's arteritis is challenging. Coronary artery bypass grafting may be required. The use of saphenous vein…”
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SFTPA2 Mutations in Familial and Sporadic Idiopathic Interstitial Pneumonia
Published in American journal of respiratory and critical care medicine (15-11-2015)Get full text
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The chemokine and chemokine receptor profile of infiltrating cells in the wall of arteries with cardiac allograft vasculopathy is indicative of a memory T-helper 1 response
Published in Circulation (New York, N.Y.) (10-10-2006)“…Despite improvement in short-term patient survival after heart transplantation (HTx), long-term survival rates have not improved much, mainly because of…”
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Long-term cardiovascular effects of neonatal dexamethasone treatment: hemodynamic follow-up by left ventricular pressure-volume loops in rats
Published in Journal of applied physiology (1985) (01-02-2008)“…1 Department of Cardiology, Leiden University Medical Center, Leiden University, Leiden; Departments of 2 Neonatology and 3 Pathology, Utrecht University…”
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Type IV collagen degradation in the myocardial basement membrane after unloading of the failing heart by a left ventricular assist device
Published in Laboratory investigation (01-11-2007)“…After left ventricular assist device (LVAD) support in patients with end-stage cardiomyopathy, cardiomyocytes decrease in size. We hypothesized that during…”
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Telomerase Reverse Transcriptase Polymorphism rs2736100: A Balancing Act between Cancer and Non-Cancer Disease, a Meta-Analysis
Published in Frontiers in medicine (27-02-2018)“…The enzyme telomerase reverse transcriptase (TERT) is essential for telomere maintenance. In replicating cells, maintenance of telomere length is important for…”
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The Extent of Inflammatory Cell Infiltrate and Fibrosis in Lungs of Telomere- and Surfactant-Related Familial Pulmonary Fibrosis
Published in Frontiers in medicine (24-09-2021)“…Familial pulmonary fibrosis (FPF) is a monogenic disease most commonly involving telomere- ( TERT ) or surfactant- ( SFTP ) related mutations. These mutations…”
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What Is New in Dilatation of the Ascending Aorta? Review of Current Literature and Practical Advice for the Cardiologist
Published in Circulation (New York, N.Y.) (01-03-2011)Get full text
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Suppression of physiological cardiomyocyte proliferation in the rat pup after neonatal glucocorticosteroid treatment
Published in Basic research in cardiology (01-01-2006)“…Glucocorticosteroids (mostly dexamethasone) are widely used to prevent chronic lung disease in premature infants. Neonatal rats treated with dexamethasone have…”
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T cells in Cardiac Allograft Vasculopathy Are Skewed to Memory Th‐1 Cells in the Presence of a Distinct Th‐2 Population
Published in American journal of transplantation (01-05-2008)“…Cardiac allograft vasculopathy (CAV) in heart transplantation (HTx) patients remains the major complication for long‐term survival, due to concentric neointima…”
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Unfavourable outcome of glucocorticoid treatment in suspected idiopathic pulmonary fibrosis
Published in Respirology (Carlton, Vic.) (01-03-2018)“…ABSTRACT Background and objective The diagnostic classification of ‘possible idiopathic pulmonary fibrosis (posIPF)’ is characterized by a radiological pattern…”
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Negative MR contrast caused by USPIO uptake in lymph nodes may lead to false positive observations with in vivo visualization of murine atherosclerotic plaque
Published in Atherosclerosis (01-05-2010)“…Abstract Objective USPIOs are used clinically as contrast agent for magnetic resonance imaging (MRI) of lymph nodes, and in research settings for MRI of…”
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Long‐term expanding human airway organoids for disease modeling
Published in The EMBO journal (15-02-2019)“…Organoids are self‐organizing 3D structures grown from stem cells that recapitulate essential aspects of organ structure and function. Here, we describe a…”
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Left ventricular pressure-volume relationships during normal growth and development in the adult rat - studies in 8- and 50-week-old male Wistar rats
Published in Acta physiologica Scandinavica (01-11-2005)“…Aims: Left ventricular (LV) pressure–volume relations provide relatively load‐independent indexes of systolic and diastolic LV function, but few data are…”
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