Search Results - "van Nuland, Rick"
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Quantitative Dissection and Stoichiometry Determination of the Human SET1/MLL Histone Methyltransferase Complexes
Published in Molecular and Cellular Biology (01-05-2013)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Histone H4 Lysine 20 (H4K20) Methylation, Expanding the Signaling Potential of the Proteome One Methyl Moiety at a Time
Published in Molecular & cellular proteomics (01-03-2016)“…Covalent post-translational modifications (PTMs) of proteins can regulate the structural and functional state of a protein in the absence of primary changes in…”
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Sharing sensitive data in life sciences: an overview of centralized and federated approaches
Published in Briefings in bioinformatics (05-06-2024)“…Abstract Biomedical data are generated and collected from various sources, including medical imaging, laboratory tests and genome sequencing. Sharing these…”
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Nucleosomal DNA binding drives the recognition of H3K36-methylated nucleosomes by the PSIP1-PWWP domain
Published in Epigenetics & chromatin (08-05-2013)“…Recognition of histone modifications by specialized protein domains is a key step in the regulation of DNA-mediated processes like gene transcription. The…”
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A domino effect in drug action: from metabolic assault towards parasite differentiation
Published in Molecular microbiology (01-01-2011)“…Summary Awareness is growing that drug target validation should involve systems analysis of cellular networks. There is less appreciation, though, that the…”
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Multivalent engagement of TFIID to nucleosomes
Published in PloS one (11-09-2013)“…The process of eukaryotic transcription initiation involves the assembly of basal transcription factor complexes on the gene promoter. The recruitment of TFIID…”
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Effect of Intravenous Alteplase Treatment on First-Line Stent Retriever Versus Aspiration Alone During Endovascular Treatment
Published in Stroke (1970) (01-11-2022)“…Background: We aimed to assess whether the effect of intravenous alteplase treatment (IVT) before endovascular treatment (EVT) on outcome is modified by…”
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Collateral-based selection for endovascular treatment of acute ischaemic stroke in the late window (MR CLEAN-LATE): 2-year follow-up of a phase 3, multicentre, open-label, randomised controlled trial in the Netherlands
Published in Lancet neurology (01-09-2024)“…The MR CLEAN-LATE trial provided evidence for the safety and efficacy of endovascular treatment for acute ischaemic stroke within the late window (after 6–24…”
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Multicenter randomized clinical trial of endovascular treatment for acute ischemic stroke. The effect of periprocedural medication: acetylsalicylic acid, unfractionated heparin, both, or neither (MR CLEAN-MED). Rationale and study design
Published in Current controlled trials in cardiovascular medicine (14-07-2020)“…Despite evidence of a quite large beneficial effect of endovascular treatment (EVT) for ischemic stroke caused by anterior circulation large vessel occlusion,…”
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Regulation of vitamin D receptor function in MEN1-related parathyroid adenomas
Published in Molecular and cellular endocrinology (10-12-2009)“…Multiple endocrine neoplasia type 1 (MEN1) is a heriditary syndrome characterised by the occurrence of parathyroid, gastroenteropancreatic and pituitary…”
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Multivalent Engagement of TFIID to Nucleosomes: e73495
Published in PloS one (01-09-2013)“…The process of eukaryotic transcription initiation involves the assembly of basal transcription factor complexes on the gene promoter. The recruitment of TFIID…”
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Synergies Among Health Data Projects with Cancer Use Cases Based on Health Standards
Published in Studies in health technology and informatics (22-08-2024)“…We are creating a synergy among European Health Data Space projects (e.g., IDERHA, EUCAIM, ASCAPE, iHELP, Bigpicture, and HealthData@EU pilot project) via…”
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