Search Results - "van Nuenen, A"

Miravirsen dosing in chronic hepatitis C patients results in decreased microRNA‐122 levels without affecting other microRNAs in plasma by Ree, M. H., Meer, A. J., Nuenen, A. C., Bruijne, J., Ottosen, S., Janssen, H. L., Kootstra, N. A., Reesink, H. W.

“…Summary Background MicroRNA‐122 (miR‐122) is an important host factor for hepatitis C virus replication. Administration of miravirsen, an anti‐miR‐122…”
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P09-14. Emergence of b12 resistant rapidly replication HIV-1 variants during natural infection in the absence of humoral or cellular immune pressure by Bunnik, E, Lobbrecht, M, Pisas, L, van Nuenen, A, Schuitemaker, H

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P07-04. HIV-1 evolution in mother to child transmission and pediatric disease progression by Dispinseri, S, Cavarelli, M, van Nuenen, A, Schuitemaker, H, Scarlatti, G

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Identification of Campylobacter jejuni promoter sequences by Wösten, M M, Boeve, M, Koot, M G, van Nuenen, A C, van der Zeijst, B A

“…A promoterless lacZ shuttle vector, which allowed screening of promoters by beta-galactosidase activity in Campylobacter jejuni and Escherichia coli, was…”
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Increased Neutralization Sensitivity and Reduced Replicative Capacity of Human Immunodeficiency Virus Type 1 after Short-Term In Vivo or In Vitro Passage through Chimpanzees by Beaumont, T, Broersen, S, van Nuenen, A, Huisman, H G, de Roda Husman, A M, Heeney, J L, Schuitemaker, H

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Reversal of Human Immunodeficiency Virus Type 1 IIIB to a Neutralization-Resistant Phenotype in an Accidentally Infected Laboratory Worker with a Progressive Clinical Course by Beaumont, T, van Nuenen, A, Broersen, S, Blattner, W A, Lukashov, V V, Schuitemaker, H

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Miravirsen dosing in chronic hepatitis C patients results in decreased micro RNA ‐122 levels without affecting other micro RNA s in plasma by van der Ree, M. H., van der Meer, A. J., van Nuenen, A. C., de Bruijne, J., Ottosen, S., Janssen, H. L., Kootstra, N. A., Reesink, H. W.

“…Summary Background Micro RNA ‐122 (miR‐122) is an important host factor for hepatitis C virus replication. Administration of miravirsen, an anti‐miR‐122…”
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Emergence of monoclonal antibody b12-resistant human immunodeficiency virus type 1 variants during natural infection in the absence of humoral or cellular immune pressure by Bunnik, Evelien M, van Gils, Marit J, Lobbrecht, Marilie S D, Pisas, Linaida, Nanlohy, Nening M, van Baarle, Debbie, van Nuenen, Ad C, Hessell, Ann J, Schuitemaker, Hanneke

“…Human immunodeficiency virus type 1 (HIV-1) resistance to broadly neutralizing antibodies such as b12, which targets the highly conserved CD4-binding site,…”
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Increased Sensitivity to CD4 Binding Site-Directed Neutralization following In Vitro Propagation on Primary Lymphocytes of a Neutralization-Resistant Human Immunodeficiency Virus IIIB Strain Isolated from an Accidentally Infected Laboratory Worker by BEAUMONT, Tim, QUAKKELAAR, Esther, VAN NUENEN, Ad, PANTOPHLET, Ralph, SCHUITEMAKER, Hanneke

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Changing sensitivity to broadly neutralizing antibodies b12, 2G12, 2F5, and 4E10 of primary subtype B human immunodeficiency virus type 1 variants in the natural course of infection by Bunnik, Evelien M, van Gils, Marit J, Lobbrecht, Marilie S.D, Pisas, Linaida, van Nuenen, Ad C, Schuitemaker, Hanneke

“…Abstract The conserved nature of the epitopes of the four broadly neutralizing antibodies (BNAbs), b12, 2G12, 2F5, and 4E10, may imply that the sensitivity of…”
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Escape of human immunodeficiency virus type 1 from broadly neutralizing antibodies is not associated with a reduction of viral replicative capacity in vitro by Quakkelaar, Esther D, Bunnik, Evelien M, van Alphen, Floris P.J, Boeser-Nunnink, Brigitte D.M, van Nuenen, Ad C, Schuitemaker, Hanneke

“…Abstract Although the majority of primary HIV-1 variants can be neutralized by broadly neutralizing antibodies such as b12, 2G12, 2F5 and 4E10, resistance to…”
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T cell line passage can select for pre-existing neutralization-sensitive variants from the quasispecies of primary human immunodeficiency virus type-1 isolates by Quakkelaar, Esther D, Beaumont, Tim, van Nuenen, Ad C, van Alphen, Floris P.J, Boeser-Nunnink, Brigitte D.M, van 't Wout, Angélique B, Schuitemaker, Hanneke

“…Abstract Primary human immunodeficiency type 1 viruses (HIV-1) resist antibody neutralization but become sensitive after passage through T cell lines. We and…”
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