Search Results - "van Moorsel, Marc"

VWF-targeted thrombolysis to overcome rh-tPA resistance in experimental murine ischemic stroke models by van Moorsel, Marc V. A., de Maat, Steven, Vercruysse, Kristof, van Leeuwen, Esther M., Jacqmarcq, Charlène, Bonnard, Thomas, Vivien, Denis, van der Worp, H. Bart, Dijkhuizen, Rick M., Maas, Coen

“…•Microlyse is noninferior to rh-tPA when AIS is driven by fibrin-rich thrombi, but superior in AIS driven by platelet-rich thrombi.•VWF-targeted plasminogen…”
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VhH anti‐thrombomodulin clone 1 inhibits TAFI activation and enhances fibrinolysis in human whole blood under flow by van Moorsel, Marc V. A., Poolen, Geke C., Koekman, Cornelis A., Verhoef, Sandra, de Maat, Steven, Barendrecht, Arjan, van Kleef, Nadine D., Meijers, Joost C. M., Schiffelers, Raymond M., Maas, Coen, Urbanus, Rolf T.

“…Background Thrombomodulin on endothelial cells can form a complex with thrombin. This complex has both anticoagulant properties, by activating protein C, and…”
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A head-to-head comparison of conjugation methods for VHHs: Random maleimide-thiol coupling versus controlled click chemistry by van Moorsel, Marc V.A., Urbanus, Rolf T., Verhoef, S., Koekman, C.A., Vink, Maurice, Vermonden, T., Maas, Coen, Pasterkamp, Gerard, Schiffelers, Raymond M.

“…[Display omitted] Targeted delivery of therapeutics is an attractive strategy for vascular diseases. Recently, variable domains of heavy-chain-only antibodies…”
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Microlyse: a thrombolytic agent that targets VWF for clearance of microvascular thrombosis by de Maat, Steven, Clark, Chantal C., Barendrecht, Arjan D., Smits, Simone, van Kleef, Nadine D., El Otmani, Hinde, Waning, Manon, van Moorsel, Marc, Szardenings, Michael, Delaroque, Nicolas, Vercruysse, Kristof, Urbanus, Rolf T., Sebastian, Silvie, Lenting, Peter J., Hagemeyer, Christoph, Renné, Thomas, Vanhoorelbeke, Karen, Tersteeg, Claudia, Maas, Coen

“…Thrombotic microangiopathies are hallmarked by attacks of disseminated microvascular thrombosis. In thrombotic thrombocytopenic purpura (TTP), this is caused…”
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Thrombo-Inflammation in Cardiovascular Disease: An Expert Consensus Document from the Third Maastricht Consensus Conference on Thrombosis by d'Alessandro, Elisa, Becker, Christian, Bergmeier, Wolfgang, Bode, Christoph, Bourne, Joshua H, Brown, Helena, Buller, Harry R, Ten Cate-Hoek, Arina J, Ten Cate, Vincent, van Cauteren, Yvonne J M, Cheung, Yam F H, Cleuren, Audrey, Coenen, Danielle, Crijns, Harry J G M, de Simone, Ilaria, Dolleman, Sophie C, Klein, Christine Espinola, Fernandez, Delia I, Granneman, Lianne, van T Hof, Arnoud, Henke, Peter, Henskens, Yvonne M C, Huang, Jingnan, Jennings, Lisa K, Jooss, Natalie, Karel, Mieke, van den Kerkhof, Danique, Klok, Frederik A, Kremers, Bram, Lämmle, Bernhard, Leader, Avi, Lundstrom, Annika, Mackman, Nigel, Mannucci, Pier M, Maqsood, Zahra, van der Meijden, Paola E J, van Moorsel, Marc, Moran, Luis A, Morser, John, van Mourik, Manouk, Navarro, Stefano, Neagoe, Raluca A I, Olie, Renske H, van Paridon, Pauline, Posma, Jens, Provenzale, Isabella, Reitsma, Pieter H, Scaf, Billy, Schurgers, Leon, Seelig, Jaap, Siegbahn, Agneta, Siegerink, Bob, Soehnlein, Oliver, Soriano, Eva Maria, Sowa, Marcin A, Spronk, Henri M H, Storey, Robert F, Tantiwong, Chukiat, Veninga, Alicia, Wang, Xueqing, Watson, Steve P, Weitz, Jeff, Zeerleder, Sacha S, Ten Cate, Hugo

“…Thrombo-inflammation describes the complex interplay between blood coagulation and inflammation that plays a critical role in cardiovascular diseases. The…”
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Iron nanomedicines induce Toll-like receptor activation, cytokine production and complement activation by Verhoef, Johan J.F, de Groot, A. Marit, van Moorsel, Marc, Ritsema, Jeffrey, Beztsinna, Nataliia, Maas, Coen, Schellekens, Huub

“…Abstract Approximately a dozen of intravenous iron nanomedicines gained marketing authorization in the last two decades. These products are generally…”
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