Search Results - "van Loon, Tim"

Left atrial remodeling in mitral regurgitation: A combined experimental-computational study by Bouwmeester, Sjoerd, van Loon, Tim, Ploeg, Meike, Mast, Thomas P, Verzaal, Nienke J, van Middendorp, Lars B, Strik, Marc, van Nieuwenhoven, Frans A, Dekker, Lukas R, Prinzen, Frits W, Lumens, Joost, Houthuizen, Patrick

“…Aims Progressive changes to left atrial (LA) structure and function following mitral regurgitation (MR) remain incompletely understood. This study aimed to…”
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Virtual pacing of a patient’s digital twin to predict left ventricular reverse remodelling after cardiac resynchronization therapy by Koopsen, Tijmen, Gerrits, Willem, van Osta, Nick, van Loon, Tim, Wouters, Philippe, Prinzen, Frits W, Vernooy, Kevin, Delhaas, Tammo, Teske, Arco J, Meine, Mathias, Cramer, Maarten J, Lumens, Joost

“…Abstract Aims Identifying heart failure (HF) patients who will benefit from cardiac resynchronization therapy (CRT) remains challenging. We evaluated whether…”
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Parameter subset reduction for imaging-based digital twin generation of patients with left ventricular mechanical discoordination by Koopsen, Tijmen, van Osta, Nick, van Loon, Tim, Meiburg, Roel, Huberts, Wouter, Beela, Ahmed S, Kirkels, Feddo P, van Klarenbosch, Bas R, Teske, Arco J, Cramer, Maarten J, Bijvoet, Geertruida P, van Stipdonk, Antonius, Vernooy, Kevin, Delhaas, Tammo, Lumens, Joost

“…Integration of a patient's non-invasive imaging data in a digital twin (DT) of the heart can provide valuable insight into the myocardial disease substrates…”
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Uncertainty Quantification of Regional Cardiac Tissue Properties in Arrhythmogenic Cardiomyopathy Using Adaptive Multiple Importance Sampling by van Osta, Nick, Kirkels, Feddo P, van Loon, Tim, Koopsen, Tijmen, Lyon, Aurore, Meiburg, Roel, Huberts, Wouter, Cramer, Maarten J, Delhaas, Tammo, Haugaa, Kristina H, Teske, Arco J, Lumens, Joost

“…Computational models of the cardiovascular system are widely used to simulate cardiac (dys)function. Personalization of such models for patient-specific…”
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A Lumped Two-Compartment Model for Simulation of Ventricular Pump and Tissue Mechanics in Ischemic Heart Disease by Koopsen, Tijmen, Van Osta, Nick, Van Loon, Tim, Van Nieuwenhoven, Frans A, Prinzen, Frits W, Van Klarenbosch, Bas R, Kirkels, Feddo P, Teske, Arco J, Vernooy, Kevin, Delhaas, Tammo, Lumens, Joost

“…Computational modeling of cardiac mechanics and hemodynamics in ischemic heart disease (IHD) is important for a better understanding of the complex relations…”
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Mitral regurgitation in heart failure with preserved ejection fraction: The interplay of valve, ventricle, and atrium by Dhont, Sebastiaan, Acker, Gitte, Loon, Tim, Verbrugge, Frederik H., Verwerft, Jan, Deferm, Sébastien, Churchill, Timothy W., Mullens, Wilfried, Lumens, Joost, Bertrand, Philippe B.

“…Mitral regurgitation (MR) is highly prevalent among patients with heart failure and preserved ejection fraction (HFpEF). Despite this combination being closely…”
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Electromechanical substrate characterization in arrhythmogenic cardiomyopathy using imaging-based patient-specific computer simulations by van Osta, Nick, Kirkels, Feddo, Lyon, Aurore, Koopsen, Tijmen, van Loon, Tim, Cramer, Maarten-Jan, Teske, Arco J, Delhaas, Tammo, Lumens, Joost

“…Abstract Aims Arrhythmogenic cardiomyopathy (AC) is an inherited cardiac disease, characterized by life-threatening ventricular arrhythmias and progressive…”
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Monitoring of Myocardial Involvement in Early Arrhythmogenic Right Ventricular Cardiomyopathy Across the Age Spectrum by Kirkels, Feddo P., van Osta, Nick, Rootwelt-Norberg, Christine, Chivulescu, Monica, van Loon, Tim, Aabel, Eivind W., Castrini, Anna I., Lie, Øyvind H., Asselbergs, Folkert W., Delhaas, Tammo, Cramer, Maarten J., Teske, Arco J., Haugaa, Kristina H., Lumens, Joost

“…Arrhythmogenic right ventricular cardiomyopathy (ARVC) is characterized by fibrofatty replacement of primarily the right ventricular myocardium, a substrate…”
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Parameter subset reduction for patient-specific modelling of arrhythmogenic cardiomyopathy-related mutation carriers in the CircAdapt model by van Osta, Nick, Lyon, Aurore, Kirkels, Feddo, Koopsen, Tijmen, van Loon, Tim, Cramer, Maarten J, Teske, Arco J, Delhaas, Tammo, Huberts, Wouter, Lumens, Joost

“…Arrhythmogenic cardiomyopathy (AC) is an inherited cardiac disease, clinically characterized by life-threatening ventricular arrhythmias and progressive…”
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Parameter subset reduction for patient-specific modelling of arrhythmogenic cardiomyopathy-related mutation carriers in the CircAdapt model by van Osta, Nick, Lyon, Aurore, Kirkels, Feddo, Koopsen, Tijmen, van Loon, Tim, Cramer, Maarten J., Teske, Arco J., Delhaas, Tammo, Huberts, Wouter, Lumens, Joost

“…Arrhythmogenic cardiomyopathy (AC) is an inherited cardiac disease, clinically characterized by life-threatening ventricular arrhythmias and progressive…”
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Left Atrial Function in Patients with Titin Cardiomyopathy by HENKENS, MICHIEL T.H.M., RAAFS, ANNE G., VANLOON, TIM, VOS, JACQUELINE L., VANDENWIJNGAARD, ARTHUR, BRUNNER, HAN G., KRAPELS, INGRID P.C., KNACKSTEDT, CHRISTIAN, GERRETSEN, SUZANNE, HAZEBROEK, MARK R., VERNOOY, KEVIN, NIJVELDT, ROBIN, LUMENS, JOOST, VERDONSCHOT, JOB A.J.

“…Truncating variants in titin (TTNtv) are the most prevalent genetic etiology of dilated cardiomyopathy (DCM). Although TTNtv has been associated with atrial…”
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Increased myocardial stiffness more than impaired relaxation function limits cardiac performance during exercise in heart failure with preserved ejection fraction: a virtual patient study by van Loon, Tim, Knackstedt, Christian, Cornelussen, Richard, Reesink, Koen D, Brunner La Rocca, Hans-Peter, Delhaas, Tammo, van Empel, Vanessa, Lumens, Joost

“…The relative impact of left ventricular (LV) diastolic dysfunction (LVDD) and impaired left atrial (LA) function on cardiovascular haemodynamics in heart…”
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Downfolding the Su-Schrieffer-Heeger model by Schobert, Arne, Berges, Jan, Wehling, Tim, van Loon, Erik

“…Charge-density waves are responsible for symmetry-breaking displacements of atoms and concomitant changes in the electronic structure. Linear response…”
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Thermodynamics of the metal-insulator transition in the extended Hubbard model by Schüler, Malte, van Loon, Erik, Katsnelson, Mikhail, Wehling, Tim

“…In contrast to the Hubbard model, the extended Hubbard model, which additionally accounts for non-local interactions, lacks systemic studies of thermodynamic…”
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