Search Results - "van Loon, Raoul"
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A personalised computational model of the impact of COVID-19 on lung function under mechanical ventilation
Published in Computers in biology and medicine (01-12-2024)“…This work proposes a modelling framework to analyse flow and pressure distributions throughout the lung of mechanically ventilated COVID-19 patients. The…”
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An implicit solver for 1D arterial network models
Published in International journal for numerical methods in biomedical engineering (01-07-2017)“…In this study, the 1D blood flow equations are solved using a newly proposed enhanced trapezoidal rule method (ETM), which is an extension to the simplified…”
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Personalising cardiovascular network models in pregnancy: A two‐tiered parameter estimation approach
Published in International journal for numerical methods in biomedical engineering (01-11-2021)“…Uterine artery Doppler waveforms are often studied to determine whether a patient is at risk of developing pathologies such as pre‐eclampsia. Many uterine…”
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Computational investigation of the Laplace law in compression therapy
Published in Journal of biomechanics (06-03-2019)“…This study aims to use computational methods for elucidating the effect of limb shape on subgarment and subcutaneous pressures, stresses and strains. A…”
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A data-driven model to study utero-ovarian blood flow physiology during pregnancy
Published in Biomechanics and modeling in mechanobiology (01-08-2019)“…In this paper, we describe a mathematical model of the cardiovascular system in human pregnancy. An automated, closed-loop 1D–0D modelling framework was…”
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Investigation of Shape with Patients Suffering from Unilateral Lymphoedema
Published in Annals of biomedical engineering (01-01-2018)“…This study investigates the use of a 3D depth sensing camera for analysing the shape of lymphoedematous arms, and seeks to identify suitable metrics for…”
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7
Development of non-invasive biomarkers for pre-eclampsia through data-driven cardiovascular network models
Published in Scientific reports (04-10-2024)“…Computational models can be at the basis of new powerful technologies for studying and classifying disorders like pre-eclampsia, where it is difficult to…”
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The effect of prone positioning on maternal haemodynamics and fetal wellbeing in the third trimester–A primary cohort study with a scoping review
Published in PloS one (11-10-2023)“…Introduction Supine sleep position is associated with stillbirth, likely secondary to inferior vena cava compression, and a reduction in cardiac output (CO)…”
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Determining the combined effect of the lymphatic valve leaflets and sinus on resistance to forward flow
Published in Journal of biomechanics (15-10-2015)“…Abstract The lymphatic system is vital to a proper maintenance of fluid and solute homeostasis. Collecting lymphatics are composed of actively contracting…”
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10
Data-driven modelling of the FRC network for studying the fluid flow in the conduit system
Published in Engineering applications of artificial intelligence (01-06-2017)“…The human immune system is characterized by enormous cellular and anatomical complexity. Lymph nodes are key centers of immune reactivity, organized into…”
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Integrated geometric and mechanical analysis of an image-based lymphatic valve
Published in Journal of biomechanics (07-11-2017)“…Lymphatic valves facilitate the lymphatic system’s role in maintaining fluid homeostasis. Malformed valves are found in several forms of primary lymphœdema,…”
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12
Formulation of Generalized Mass Transfer Correlations for Blood Oxygenator Design
Published in Journal of biomechanical engineering (01-03-2017)“…This paper numerically investigates non-Newtonian blood flow with oxygen and carbon dioxide transport across and along an array of uniformly square and…”
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Pore-Scale Modeling of Non-Newtonian Shear-Thinning Fluids in Blood Oxygenator Design
Published in Journal of biomechanical engineering (01-05-2016)“…This paper reviews and further develops pore-scale computational flow modeling techniques used for creeping flow through orthotropic fiber bundles used in…”
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A comparative study of fractional step method in its quasi-implicit, semi-implicit and fully-explicit forms for incompressible flows
Published in International journal of numerical methods for heat & fluid flow (03-05-2016)“…Purpose – The purpose of this paper is to describe and analyse a class of finite element fractional step methods for solving the incompressible Navier-Stokes…”
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Critical Issues in Modelling Lymph Node Physiology
Published in Computation (01-03-2017)“…In this study, we discuss critical issues in modelling the structure and function of lymph nodes (LNs), with emphasis on how LN physiology is related to its…”
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16
Patient-specific blood flow simulation through an aneurysmal thoracic aorta with a folded proximal neck
Published in International journal for numerical methods in biomedical engineering (01-08-2011)“…Transient blood flow through a geometrically patient‐specific human aorta with a thoracic aortic aneurysm (TAA) is carried out. Special attention is given to…”
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Influences of domain extensions to a moderately stenosed patient‐specific carotid bifurcation: Investigation of wall quantities
Published in International journal of numerical methods for heat & fluid flow (01-01-2011)“…Purpose - The purpose of this paper is to numerically study blood flow through a subject-specific carotid artery with a moderately severe stenosis, also to…”
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Influences of domain extensions to a moderately stenosed patient-specific carotid bifurcation
Published in International journal of numerical methods for heat & fluid flow (20-11-2011)“…Purpose - The purpose of this paper is to numerically study blood flow through a subject-specific carotid artery with a moderately severe stenosis, also to…”
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A Computational Pipeline to Investigate Longitudinal Blood Flow Changes in the Circle of Willis of Patients with Stable and Growing Aneurysms
Published in Annals of biomedical engineering (01-08-2024)“…Changes in cerebral blood flow are often associated with the initiation and development of different life-threatening medical conditions including aneurysm…”
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Transient changes during microwave ablation simulation : a comparative shape analysis
Published in Biomechanics and modeling in mechanobiology (01-02-2023)“…Microwave ablation therapy is a hyperthermic treatment for killing cancerous tumours whereby microwave energy is dispersed into a target tissue region…”
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