Search Results - "van Leeuwen, F.N"
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Pharmacogenetics of Chemotherapy Response in Osteosarcoma: A Genetic Variant in SLC7A8 is Associated with Progressive Disease
Published in Clinical therapeutics (01-08-2017)“…Associations between genetic variants and progressive disease (primary tumor and/or metastasis growth or formation up to 3 months after end of adjuvant…”
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Contribution to Neotoma: Hallwilersee (Switzerland) pollen and diatoms
Published in Vegetation history and archaeobotany (01-07-2023)“…Pollen and diatoms studied in the sediments of Hallwilersee (Switzerland) covering the past six centuries are submitted to ALPADABA in Neotoma…”
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Pollen productivity estimates for quantitative reconstruction of vegetation cover on the Swiss Plateau
Published in Holocene (Sevenoaks) (01-01-2007)“…We present the first step to quantitatively reconstruct vegetation cover in central Europe. Modern vegetation and pollen deposition were compared for 20 small…”
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Climatic change and contemporaneous land-use phases north and south of the Alps 2300 BC to 800 AD
Published in Quaternary science reviews (01-06-2003)“…Fluctuations in the Δ 14C curve and subsequent gaps of archaeological findings at 800–650 and 400–100 BC in western and central Europe may indicate major…”
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Pollen productivity, dispersal, and correction factors for major tree taxa in the Swiss Alps based on pollen-trap results
Published in Review of palaeobotany and palynology (01-12-2008)“…Annual pollen traps in the period AD 1997–2005 were analysed to determine pollen-accumulation rates (PAR; grains deposited per unit-area and unit time) for…”
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Migration and population expansion of Abies, Fagus, Picea, and Quercus since 15000 years in and across the Alps, based on pollen-percentage threshold values
Published in Quaternary science reviews (01-03-2005)“…Aims: The aim of this study is to explore the migration (colonization of new areas) and subsequent population expansion (within an area) since 15 ka cal BP of…”
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Fossil Pollen as a Guide to Conservation in the Galápagos
Published in Science (American Association for the Advancement of Science) (21-11-2008)“…Paleoecological evidence from the past 8000 years in the Galápagos Islands shows that six presumed introduced or doubtfully native species (Ageratum…”
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Millennial multi-proxy reconstruction of oasis dynamics in Jordan, by the Dead Sea
Published in Vegetation history and archaeobotany (01-09-2018)“…Vegetation reconstructions in the Dead Sea region based on sediment records are potentially biased, because the vast majority of them derive from the western…”
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The effect of climate variability on pollen productivity, AD 1975-2000, recorded in a Sphagnum peat hummock
Published in Holocene (Sevenoaks) (01-03-2006)“…Pollen accumulation rates and pollen percentages from a Sphagnum peat hummock in the Jura Mountains were used to determine past pollen deposition. Post-bomb…”
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Interactions of climate and land use documented in the varved sediments of Seebergsee in the Swiss Alps
Published in Holocene (Sevenoaks) (01-01-2002)“…This paper presents a multiproxy high-resolution study of the past 2600 years for Seebergsee, a small Swiss lake with varved sediments at the present tree-line…”
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Erratum to “Palynostratigraphy of the last centuries in Switzerland based on 23 lake and mire deposits: chronostratigraphic pollen markers, regional patterns, and local histories” [Rev. Palaeobot. Palynol. 108 (2000) 85–142]
Published in Review of palaeobotany and palynology (01-04-2001)Get full text
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Holocene tree immigration and the chironomid fauna of a small Swiss subalpine lake (Hinterburgsee, 1515 m asl)
Published in Palaeogeography, palaeoclimatology, palaeoecology (2003)“…Early Holocene reforestation by stone pine ( Pinus cembra) and tree birch ( Betula pubescens) took place ca. 500 years after the end of the Younger Dryas at…”
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B-lineage transcription factors and cooperating gene lesions required for leukemia development
Published in Leukemia (01-03-2013)“…Differentiation of hematopoietic stem cells into B lymphocytes requires the concerted action of specific transcription factors, such as RUNX1, IKZF1, E2A, EBF1…”
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Tumor suppressor IKZF1 mediates glucocorticoid resistance in B-cell precursor acute lymphoblastic leukemia
Published in Leukemia (01-07-2016)Get full text
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IKZF1 deletions predict relapse in uniformly treated pediatric precursor B-ALL
Published in Leukemia (01-07-2010)“…Relapse is the most common cause of treatment failure in pediatric acute lymphoblastic leukemia (ALL) and is often difficult to predict. To explore the…”
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Integrated use of minimal residual disease classification and IKZF1 alteration status accurately predicts 79% of relapses in pediatric acute lymphoblastic leukemia
Published in Leukemia (01-02-2011)“…Response to therapy as determined by minimal residual disease (MRD) is currently used for stratification in treatment protocols for pediatric acute…”
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Palynostratigraphy of the last centuries in Switzerland based on 23 lake and mire deposits: chronostratigraphic pollen markers, regional patterns, and local histories
Published in Review of palaeobotany and palynology (2000)“…A total of 23 pollen diagrams [stored in the Alpine Palynological Data-Base (ALPADABA), Geobotanical Institute, Bern] cover the last 100 to over 1000 years…”
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Independent development of lymphoid and histiocytic malignancies from a shared early precursor
Published in Leukemia (01-04-2016)Get full text
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Postglacial change of the floristic diversity gradient in Europe
Published in Nature communications (28-11-2019)“…Climate warming is expected to cause a poleward spread of species, resulting in increased richness at mid to high latitudes and weakening the latitudinal…”
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Long-Term Responses of Mediterranean Mountain Forests to Climate Change, Fire and Human Activities in the Northern Apennines (Italy)
Published in Ecosystems (New York) (01-09-2021)“…Fagus sylvatica (beech) dominates the montane forests of the Apennines and builds old-growth high-conservation value stands. However, recent severe…”
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