Search Results - "van Leeuwen, Anoek L.I."
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Therapeutically Targeting Microvascular Leakage In Experimental Hemorrhagic Shock: A Systematic Review and Meta-Analysis
Published in Shock (Augusta, Ga.) (22-04-2021)Get full text
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Microcirculatory perfusion disturbances following cardiopulmonary bypass: a systematic review
Published in Critical care (London, England) (13-05-2020)“…Microcirculatory perfusion disturbances are associated with increased morbidity and mortality in patients undergoing cardiac surgery with cardiopulmonary…”
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Therapeutically Targeting Microvascular Leakage in Experimental Hemorrhagic SHOCK: A Systematic Review and Meta-Analysis
Published in Shock (Augusta, Ga.) (01-12-2021)“…Microvascular leakage is proposed as main contributor to disturbed microcirculatory perfusion following hemorrhagic shock and fluid resuscitation, leading to…”
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Microvascular Alterations During Cardiac Surgery Using a Heparin or Phosphorylcholine-Coated Circuit
Published in Journal of cardiothoracic and vascular anesthesia (01-04-2020)“…Heparin biocompatible coating frequently is used to reduce inflammation and blood coagulation during cardiopulmonary bypass (CPB) in cardiac surgery. Whether…”
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Vasculotide, an Angiopoietin-1 Mimetic, Restores Microcirculatory Perfusion and Microvascular Leakage and Decreases Fluid Resuscitation Requirements in Hemorrhagic Shock
Published in Anesthesiology (Philadelphia) (01-02-2018)“…BACKGROUND:Microcirculatory dysfunction is associated with multiple organ failure and unfavorable patient outcome. We investigated whether therapeutically…”
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Modulation of angiopoietin-2 and Tie2: Organ specific effects of microvascular leakage and edema in mice
Published in Microvascular research (01-07-2024)“…Critical illness is associated with organ failure, in which endothelial hyperpermeability and tissue edema play a major role. The endothelial angiopoietin/Tie2…”
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Female sex protects against renal edema, but not lung edema, in mice with partial deletion of the endothelial barrier regulator Tie2 compared to male sex
Published in PloS one (16-11-2023)“…Background The endothelial angiopoietin/Tie2 system is an important regulator of endothelial permeability and targeting Tie2 reduces hemorrhagic shock-induced…”
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Microcirculatory perfusion disturbances following cardiac surgery with cardiopulmonary bypass are associated with in vitro endothelial hyperpermeability and increased angiopoietin-2 levels
Published in Critical care (London, England) (11-04-2019)“…Endothelial hyperpermeability following cardiopulmonary bypass (CPB) contributes to microcirculatory perfusion disturbances and postoperative complications…”
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Therapeutic interventions to restore microcirculatory perfusion following experimental hemorrhagic shock and fluid resuscitation: A systematic review
Published in Microcirculation (New York, N.Y. 1994) (01-11-2020)“…Objective Microcirculatory perfusion disturbances following hemorrhagic shock and fluid resuscitation contribute to multiple organ dysfunction and mortality…”
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Pharmacological interventions to reduce edema following cardiopulmonary bypass: A systematic review and meta-analysis
Published in Journal of critical care (01-04-2020)“…To compare the effectiveness of different types of pharmacological agents to reduce organ specific edema following cardiopulmonary bypass (CPB). Pubmed,…”
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The effect of targeting Tie2 on hemorrhagic shock-induced renal perfusion disturbances in rats
Published in Intensive care medicine experimental (17-05-2021)“…Background Hemorrhagic shock is associated with acute kidney injury and increased mortality. Targeting the endothelial angiopoietin/Tie2 system, which…”
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Preservation of renal endothelial integrity and reduction of renal edema by aprotinin does not preserve renal perfusion and function following experimental cardiopulmonary bypass
Published in Intensive care medicine experimental (25-06-2021)“…Background Acute kidney injury is a severe complication following cardiopulmonary bypass (CPB) and is associated with capillary leakage and microcirculatory…”
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