Search Results - "van Leeuwen, A. M."

Sleep restriction increases the risk of developing cardiovascular diseases by augmenting proinflammatory responses through IL-17 and CRP by van Leeuwen, Wessel M A, Lehto, Maili, Karisola, Piia, Lindholm, Harri, Luukkonen, Ritva, Sallinen, Mikael, Härmä, Mikko, Porkka-Heiskanen, Tarja, Alenius, Harri

“…Sleep restriction, leading to deprivation of sleep, is common in modern 24-h societies and is associated with the development of health problems including…”
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Active foot placement control ensures stable gait: Effect of constraints on foot placement and ankle moments by van Leeuwen, A M, van Dieën, J H, Daffertshofer, A, Bruijn, S M

“…Step-by-step foot placement control, relative to the center of mass (CoM) kinematic state, is generally considered a dominant mechanism for maintenance of gait…”
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Ankle muscles drive mediolateral center of pressure control to ensure stable steady state gait by van Leeuwen, A. M., van Dieën, J. H., Daffertshofer, A., Bruijn, S. M.

“…During steady-state walking, mediolateral gait stability can be maintained by controlling the center of pressure (CoP). The CoP modulates the moment of the…”
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Discrepancies in digital hematopathology diagnoses for consultation and expert panel analysis by van den Brand, Michiel, Nooijen, Peet T. G. A., van der Laan, Kimberly D., de Bruin, Peter C., van Leeuwen, A. M. (Gijs), Leeuwis, Jan Willem, Meijer, Jos W., Otte-Höller, Irene, Hebeda, Konnie M.

“…Digital pathology with whole-slide imaging (WSI) has a large potential to make the process of expert consultation and expert panel diagnosis more rapid and…”
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Interorgan amino acid exchange in humans: consequences for arginine and citrulline metabolism by Poll, Marcel CG van de, Siroen, Michiel PC, Leeuwen, Paul AM van, Soeters, Peter B, Melis, Gerdien C, Boelens, Petra G, Deutz, Nicolaas EP, Dejong, Cornelis HC

“…BACKGROUND: The liver plays a central role in amino acid metabolism. However, because of limited accessibility of the portal vein, human data on this subject…”
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Glutamine is an important precursor for de novo synthesis of arginine in humans by LIGTHART-MELIS, Gerdien C, VAN DE POLL, Marcel C. G, BOELENS, Petra G, DEJONG, Cornelis H. C, DEUTZ, Nicolaas E. P, VAN LEEUWEN, Paul A. M

“…A metabolic relation exists between glutamine and arginine, 2 amino acids with properties that enhance the recovery of seriously ill patients. It is possible…”
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Serological Survey of Retrovirus and Coronavirus Infections, including SARS-CoV-2, in Rural Stray Cats in The Netherlands, 2020-2022 by Duijvestijn, Mirjam B H M, Schuurman, Nancy N M P, Vernooij, Johannes C M, van Leeuwen, Michelle A J M, Bosch, Berend-Jan, van den Brand, Judith M A, Wagenaar, Jaap A, van Kuppeveld, Frank J M, Egberink, Herman F, Verhagen, Josanne H

“…Stray cats can host (zoonotic) viral pathogens and act as a source of infection for domestic cats or humans. In this cross-sectional (sero)prevalence study,…”
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Partial sleep restriction activates immune response-related gene expression pathways: experimental and epidemiological studies in humans by Aho, Vilma, Ollila, Hanna M, Rantanen, Ville, Kronholm, Erkki, Surakka, Ida, van Leeuwen, Wessel M A, Lehto, Maili, Matikainen, Sampsa, Ripatti, Samuli, Härmä, Mikko, Sallinen, Mikael, Salomaa, Veikko, Jauhiainen, Matti, Alenius, Harri, Paunio, Tiina, Porkka-Heiskanen, Tarja

“…Epidemiological studies have shown that short or insufficient sleep is associated with increased risk for metabolic diseases and mortality. To elucidate…”
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Feasibility and safety of cangrelor in patients with suboptimal P2Y12 inhibition undergoing percutaneous coronary intervention: rationale of the Dutch Cangrelor Registry by Selvarajah, A, Tavenier, A. H, Bor, W. L, Houben, V, Rasoul, S, Kaplan, E, Teeuwen, K, Hofma, S. H, Lipsic, E, Amoroso, G, van Leeuwen, M. A. H, Berg, J. M. ten, van 't Hof, A. W. J, Hermanides, R. S

“…Abstract Background Despite the advances of potent oral P2Y 12 inhibitors, their onset of action is delayed, which might have a negative impact on clinical…”
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Glycemic Control Modulates Arginine and Asymmetrical-Dimethylarginine Levels during Critical Illness by Preserving Dimethylarginine-Dimethylaminohydrolase Activity by Ellger, Björn, Richir, Milan C, van Leeuwen, Paul A. M, Debaveye, Yves, Langouche, Lies, Vanhorebeek, Ilse, Teerlink, Tom, Van den Berghe, Greet

“…In the context of the hypercatabolic response to stress, critically ill patients reveal hyperglycemia and elevated levels of asymmetrical-dimethylarginine…”
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Pre-cachexia and cachexia at diagnosis of stage III non-small-cell lung carcinoma: an exploratory study comparing two consensus-based frameworks by van der Meij, Barbara S., Schoonbeek, Coline P., Smit, Egbert F., Muscaritoli, Maurizio, van Leeuwen, Paul A. M., Langius, Jacqueline A. E.

“…Despite the development of consensus-based frameworks to define cancer cachexia, the validity and usefulness of these frameworks are relatively unknown. The…”
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Can foot placement during gait be trained? Adaptations in stability control when ankle moments are constrained by Hoogstad, L.A., van Leeuwen, A.M., van Dieën, J.H., Bruijn, S.M.

“…Accurate coordination of mediolateral foot placement, relative to the center of mass kinematic state, is one of the mechanisms which ensures mediolateral…”
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The effect of external lateral stabilization on ankle moment control during steady-state walking by van Leeuwen, A.M., van Dieën, J.H., Bruijn, S.M.

“…External lateral stabilization can help identify stability control mechanisms during steady-state walking. The degree of step-by-step foot placement control…”
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Kinetic modeling of poly(β-hydroxybutyrate) production and consumption by Paracoccus pantotrophus under dynamic substrate supply by van Aalst-van Leeuwen, M. A., Pot, M. A., van Loosdrecht, M. C. M., Heijnen, J. J.

“…The objective of the research was to obtain insights into the behavior of microorganisms under feast/famine conditions as often occur in wastewater treatment…”
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Handling of asymmetrical dimethylarginine and symmetrical dimethylarginine by the rat kidney under basal conditions and during endotoxaemia by Nijveldt, Robert J., Teerlink, Tom, van Guldener, Coen, Prins, Hubert A., van Lambalgen, Antonie A., Stehouwer, Coen D. A., Rauwerda, Jan A., van Leeuwen, Paul A. M.

“…Background. Asymmetrical dimethylarginine (ADMA) is capable of inhibiting nitric oxide synthase enzymes, whereas symmetrical dimethylarginine (SDMA) competes…”
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Perioperative arginine-supplemented nutrition in malnourished patients with head and neck cancer improves long-term survival by Buijs, Nikki, van Bokhorst-de van der Schueren, Marian AE, Langius, Jacqueline AE, Leemans, C. Rene, Kuik, Dirk J, Vermeulen, Mechteld AR, van Leeuwen, Paul AM

“…BACKGROUND: Plasma arginine concentrations are lower in patients with cancer, which indicates that arginine metabolism may be disturbed in these patients…”
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Nutritional support in patients with GVHD of the digestive tract: state of the art by van der Meij, B S, de Graaf, P, Wierdsma, N J, Langius, J A E, Janssen, J J W M, van Leeuwen, P A M, Visser, O J

“…An important complication of allo-SCT is GVHD, which commonly affects the skin, liver and digestive tract. Clinical symptoms of GVHD of the digestive tract…”
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Antioxidant enriched enteral nutrition and oxidative stress after major gastrointestinal tract surgery by van Stijn, Mireille F M, Ligthart-Melis, Gerdien C, Boelens, Petra G, Scheffer, Peter G, Teerlink, Tom, Twisk, Jos W R, Houdijk, Alexander P J, van Leeuwen, Paul A M

“…To investigate the effects of an enteral supplement containing antioxidants on circulating levels of antioxidants and indicators of oxidative stress after…”
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IL-10 signaling in dendritic cells controls IL-1β-mediated IFNγ secretion by human CD4+ T cells: relevance to inflammatory bowel disease by Veenbergen, S., Li, P., Raatgeep, H. C., Lindenbergh-Kortleve, D. J., Simons-Oosterhuis, Y., Farrel, A., Costes, L. M. M., Joosse, M. E., van Berkel, L. A., de Ruiter, L. F., van Leeuwen, M. A., Winter, D., Holland, S. M., Freeman, A. F., Wakabayashi, Y., Zhu, J., de Ridder, L., Driessen, G. J., Escher, J. C., Leonard, W. J., Samsom, J. N.

“…Uncontrolled interferon γ (IFNγ)-mediated T-cell responses to commensal microbiota are a driver of inflammatory bowel disease (IBD). Interleukin-10 (IL-10) is…”
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No increased mortality in patients with rheumatoid arthritis: up to 10 years of follow up from disease onset by Kroot, E J A, van Leeuwen, M A, van Rijswijk, M H, Prevoo, M L L, Van 't Hof, M A, van de Putte, L B A, van Riel, P L C M

“…OBJECTIVE To investigate mortality, functional capacity, and prognostic factors for mortality in an inception cohort of patients with recently diagnosed RA…”
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