Search Results - "van Laar, M"

Mycophenolate mofetil, azathioprine and tacrolimus: mechanisms in rheumatology by Broen, Jasper C. A., van Laar, Jacob M.

“…The introduction of biologic DMARDs into rheumatology has resulted in a substantial reduction of the burden of many rheumatic diseases. In the slipstream of…”
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T cells in systemic sclerosis: a reappraisal by O'REILLY, Steven, HÜGLE, Thomas, LAAR, Jacob M. Van

“…SSc is an autoimmune disease characterized by inflammation and extracellular matrix deposition that ultimately leads to loss of organ function. T cells appear…”
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Sensitivity and specificity of serum soluble interleukin-2 receptor for diagnosing sarcoidosis in a population of patients suspected of sarcoidosis by Eurelings, Laura E M, Miedema, Jelle R, Dalm, Virgil A S H, van Daele, Paul L A, van Hagen, P Martin, van Laar, Jan A M, Dik, Willem A

“…The soluble interleukin 2 receptor (sIL-2R) has been proposed as a marker of disease activity in patients with sarcoidosis. However, no studies have evaluated…”
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Editorial: Stem cell transplantation in autoimmune diseases (AID) by Schmalzing, Marc, Henes, Joerg, van Laar, Jacob M, Sullivan, Keith M

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Severe thrombotic microangiopathy after autologous stem cell transplantation in systemic sclerosis: a case report by Sharif, Maryam O., Leavis, Helen L., van Paassen, Pieter, van Rhenen, Anna, Timmermans, Sjoerd A. M. E. G., Ton, Evelien, Laar, Jacob M. van, Spierings, Julia

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Genome-wide association study in an admixed case series reveals IL12A as a new candidate in Behçet disease by Kappen, Jasper H, Medina-Gomez, Carolina, van Hagen, P Martin, Stolk, Lisette, Estrada, Karol, Rivadeneira, Fernando, Uitterlinden, Andre G, Stanford, Miles R, Ben-Chetrit, Eldat, Wallace, Graham R, Soylu, Merih, van Laar, Jan A M

“…The etiology of Behçet's disease (BD) is unknown, but widely considered an excessive T-cell mediated inflammatory response in a genetically susceptible host…”
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Efficacy and safety of selective glucocorticoid receptor modulators in comparison to glucocorticoids in arthritis, a systematic review by Safy, M, de Hair, M J H, Jacobs, J W G, Buttgereit, F, Kraan, M C, van Laar, J M

“…Long-term treatment with glucocorticoids (GCs) plays an important role in the management of arthritis patients, although the efficacy/safety balance is…”
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Regulatory T cells in psoriatic arthritis: an IL-17A-producing, Foxp3intCD161 + RORγt + ICOS + phenotype, that associates with the presence of ADAMTSL5 autoantibodies by Pouw, Juliëtte N., Olde Nordkamp, Michel A. M., van Kempen, Tessa, Concepcion, Arno N., van Laar, Jacob M., van Wijk, Femke, Spierings, Julia, Leijten, Emmerik F. A., Boes, Marianne

“…In psoriatic arthritis (PsA), predisposing class I HLA alleles, the presence of synovial clonally proliferated CD8 + T cells and autoantibodies all point…”
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A randomised controlled trial on the efficacy and tolerability with dose escalation of allopurinol 300-600 mg/day versus benzbromarone 100-200 mg/day in patients with gout by Reinders, M K, Haagsma, C, Jansen, T L Th A, van Roon, E N, Delsing, J, van de Laar, M A F J, Brouwers, J R B J

“…To compare the efficacy and tolerability of allopurinol 300-600 mg/day versus benzbromarone 100-200 mg/day used to attain a target serum urate concentration…”
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The diagnostic performance of dual energy CT for diagnosing gout: a systematic literature review and meta-analysis by Gamala, Mihaela, Jacobs, Johannes W G, van Laar, Jaap M

“…Abstract Objective This study aimed to assess the utility of dual energy CT (DECT) for diagnosing gout. Methods A systematic literature search was performed in…”
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Healthcare professionals' perceptions on barriers and facilitators to DMARD use in rheumatoid arthritis by Voshaar, M J H, van den Bemt, B J F, van de Laar, M A F J, van Dulmen, A M, Vriezekolk, J E

“…Disease-modifying anti-rheumatic drugs (DMARDs) are the cornerstone of rheumatoid arthritis (RA) treatment. However, the full benefits of DMARDs are often not…”
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Knee Joint Distraction Compared to Total Knee Arthroplasty for Treatment of End Stage Osteoarthritis: Simulating Long-Term Outcomes and Cost-Effectiveness by van der Woude, J A D, Nair, S C, Custers, R J H, van Laar, J M, Kuchuck, N O, Lafeber, F P J G, Welsing, P M J

“…In end-stage knee osteoarthritis the treatment of choice is total knee arthroplasty (TKA). An alternative treatment is knee joint distraction (KJD), suggested…”
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Soluble Interleukin-2 Receptor: A Potential Marker for Monitoring Disease Activity in IgG4-Related Disease by van Laar, J. A. M., van Hagen, P. M., Bansie, R. D., Eurelings, L. E. M., Karim, A. F., Dik, Wim A.

“…Background. IgG4-related disease (IgG4-RD) is a fibroinflammatory condition. T-cells play a crucial role in the pathogenesis, and therefore, serum soluble…”
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Adult stem cells in the treatment of autoimmune diseases by VAN LAAR, J. M, TYNDALL, A

“…During the past 10 yrs, over 700 patients suffering from severe autoimmune disease (AD) have received an autologous haematopoietic stem cell transplant as…”
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Patient-centred care in established rheumatoid arthritis by Voshaar, M.J.H., MSc, Nota, I., MSc, van de Laar, M.A.F.J., MD, PhD, van den Bemt, B.J.F., PharmD, PhD

“…Abstract Review of the evidence on patient-centred care (PCC) in rheumatoid arthritis (RA) shows that involving the patient as an individual – with unique…”
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The clinical utility of bone marker measurements in osteoporosis by Wheater, Gillian, Elshahaly, Mohsen, Tuck, Stephen P, Datta, Harish K, van Laar, Jacob M

“…Osteoporosis is characterised by low bone mass and structural deterioration of bone tissue, resulting in increased fragility and susceptibility to fracture…”
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Corrigendum to “Hydroxychloroquine Use in Lupus Patients during Pregnancy Is Associated with Longer Pregnancy Duration in Preterm Births” by Kroese, S. J., de Hair, M. J. H., Limper, M., Lely, A. T., van Laar, J. M., Derksen, R. H. W. M., Fritsch-Stork, R. D. E.

“…[This corrects the article DOI: 10.1155/2017/2810202.]…”
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MiR-29a reduces TIMP-1 production by dermal fibroblasts via targeting TGF-β activated kinase 1 binding protein 1, implications for systemic sclerosis by Ciechomska, Marzena, O'Reilly, Steven, Suwara, Monika, Bogunia-Kubik, Katarzyna, van Laar, Jacob M

“…Systemic sclerosis (SSc) is an autoimmune connective tissue disease characterised by skin and internal organs fibrosis due to accumulation of extra cellular…”
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Mortality in systemic sclerosis: an international meta-analysis of individual patient data by Ioannidis, John P A, Vlachoyiannopoulos, Panayiotis G, Haidich, Anna-Bettina, Medsger, Jr, Thomas A, Lucas, Mary, Michet, Clement J, Kuwana, Masataka, Yasuoka, Hidekata, van den Hoogen, Frank, Te Boome, Liane, van Laar, Jacob M, Verbeet, Nicolette L, Matucci-Cerinic, Marco, Georgountzos, Athanasios, Moutsopoulos, Haralampos M

“…Studies on mortality associated with systemic sclerosis have been limited by small sample sizes. We aimed to obtain large-scale evidence on survival outcomes…”
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Interference of NSAIDs with the thrombocyte inhibitory effect of aspirin: A placebo-controlled, ex vivo, serial placebo-controlled serial crossover study by Meek, I. L., Vonkeman, H. E., Kasemier, J., Movig, K. L. L., van de Laar, M. A. F. J.

“…Purpose Nonsteroidal anti-inflammatory drugs (NSAIDs) and acetylsalicylic acid (ASA) are often prescribed concurrently in patients with nociceptive pain and…”
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