Search Results - "van Kuik, Petra"

In vivo comparison of 2′-O-methyl phosphorothioate and morpholino antisense oligonucleotides for Duchenne muscular dystrophy exon skipping by Heemskerk, Hans A., de Winter, Christa L., de Kimpe, Sjef J., van Kuik-Romeijn, Petra, Heuvelmans, Niki, Platenburg, Gerard J., van Ommen, Gert-Jan B., van Deutekom, Judith C. T., Aartsma-Rus, Annemieke

“…Background Antisense‐mediated exon skipping is a putative treatment for Duchenne muscular dystrophy (DMD). Using antisense oligonucleotides (AONs), the…”
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Preclinical PK and PD Studies on 2′-O-Methyl-phosphorothioate RNA Antisense Oligonucleotides in the mdx Mouse Model by Heemskerk, Hans, de Winter, Christa, van Kuik, Petra, Heuvelmans, Niki, Sabatelli, Patrizia, Rimessi, Paola, Braghetta, Paola, van Ommen, Gert-Jan B, de Kimpe, Sjef, Ferlini, Alessandra, Aartsma-Rus, Annemieke, van Deutekom, Judith CT

“…Antisense oligonucleotides (AONs) are being developed as RNA therapeutic molecules for Duchenne muscular dystrophy. For oligonucleotides with the…”
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Triplet-repeat oligonucleotide-mediated reversal of RNA toxicity in myotonic dystrophy by Mulders, Susan A.M, van den Broek, Walther J.A.A, Wheeler, Thurman M, Croes, Huib J.E, van Kuik-Romeijn, Petra, de Kimpe, Sjef J, Furling, Denis, Platenburg, Gerard J, Gourdon, Geneviève, Thornton, Charles A, Wieringa, Bé, Wansink, Derick G

“…Myotonic dystrophy type 1 (DM1) is caused by toxicity of an expanded, noncoding (CUG)n tract in DM protein kinase (DMPK) transcripts. According to current…”
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Synthesis and in Vitro Evaluation of PNA−Peptide−DETA Conjugates as Potential Cell Penetrating Artificial Ribonucleases by Petersen, Lene, de Koning, Martijn C, van Kuik-Romeijn, Petra, Weterings, Jimmy, Pol, Christine J, Platenburg, Gerard, Overhand, Mark, van der Marel, Gijsbert A, van Boom, Jacques H

“…We report the synthesis of novel artificial ribonucleases with potentially improved cellular uptake. The design of trifunctional conjugates 1a and 1b is based…”
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Over-expression of the murine polymeric immunoglobulin receptor gene in the mammary gland of transgenic mice by DE GROOT, N, VAN KUIK-ROMEIJN, P, SANG HA LEE, DE BOER, H. A

“…The polymeric immunoglobulin receptor (pIgR), a transmembrane protein, transports dimeric IgA (dIgA) across the epithelial cells of the mucosal surfaces into…”
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Corrigendum - Over-expression of the murine polymeric immunoglobulin receptor gene in the mammary gland of transgenic mice by de Groot, Nanda, van Kuik-Romeijn, Petra, Lee, Sang He, de Boer, Herman A

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Expression of a functional mouse-human chimeric anti-CD19 antibody in the milk of transgenic mice by VAN KUIK-ROMEIJN, P, DE GROOT, N, HOOIJBERG, E, DE BOER, H. A

“…Human B cell lymphomas are suitable targets for immunotherapy. Clinical trials with mouse-human chimeric B cell-specific monoclonal antibodies (mAbs) have…”
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Over-expression of the murine pIgR gene in the mammary gland of transgenic mice influences the milk composition and reduces its nutritional value by DE GROOT, Nanda, VAN KUIK-ROMEIJN, Petra, SANG HE LEE, DE BOER, Herman A

“…The polymeric immunoglobulin receptor (pIgR) transports dimeric IgA (dIgA) across epithelial cells lining mucosal and glandular tissues, including the mammary…”
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Over-expression of the murine polymeric immunoglobulin receptor gene in the mammary gland of transgenic mice by Groot, Nanda De, Kuik-romeijn, Petra Van, Lee, Sang He, de Boer, Herman A

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