Search Results - "van Kranen, Henk J."

Functional foods and dietary supplements: Products at the interface between pharma and nutrition by Eussen, Simone R.B.M., Verhagen, Hans, Klungel, Olaf H., Garssen, Johan, van Loveren, Henk, van Kranen, Henk J., Rompelberg, Cathy J.M.

“…It is increasingly recognized that most chronic diseases of concern today are multifactorial in origin. To combat such diseases and adverse health conditions,…”
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Intravenous Lidocaine for Refractory Pain in Patients With Pancreatic Ductal Adenocarcinoma and Chronic Pancreatitis: A Multicenter Prospective Nonrandomized Pilot Study by Augustinus, Simone, Bieze, Matthanja, Van Veldhuisen, Charlotte L, Boermeester, Marja A, Bonsing, Bert A, Bouwense, Stefan A W, Bruno, Marco J, Busch, Olivier R, Ten Hoope, Werner, Kallewaard, Jan-Willem, van Kranen, Henk J, Niesters, Marieke, Schellekens, Niels C J, Steegers, Monique A H, Voermans, Rogier P, de Vos-Geelen, Judith, Wilmink, Johanna W, Van Zundert, Jan H M, van Eijck, Casper H, Besselink, Marc G, Hollmann, Markus W

“…Refractory pain is a major clinical problem in patients with pancreatic ductal adenocarcinoma (PDAC) and chronic pancreatitis (CP). New, effective therapies to…”
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XPA-deficiency in hairless mice causes a shift in skin tumor types and mutational target genes after exposure to low doses of U.V.B by DE VRIES, A, BERG, R. J. W, WIJNHOVEN, S, WESTERMAN, A, WESTER, P. W, VAN KREIJL, C. F, CAPEL, P. J. A, DE GRUIJL, F. R, VAN KRANEN, H. J, VAN STEEG, H

“…Xeroderma pigmentosum (XP) patients with a defect in the nucleotide excision repair gene XPA, develop tumors with a high frequency on sun-exposed areas of the…”
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MECP2 variation in Rett syndrome—An overview of current coverage of genetic and phenotype data within existing databases by Townend, Gillian S., Ehrhart, Friederike, Kranen, Henk J., Wilkinson, Mark, Jacobsen, Annika, Roos, Marco, Willighagen, Egon L., Enckevort, David, Evelo, Chris T., Curfs, Leopold M. G.

“…Rett syndrome (RTT) is a monogenic rare disorder that causes severe neurological problems. In most cases, it results from a loss‐of‐function mutation in the…”
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Preferences for genetic testing for colorectal cancer within a population-based screening program: a discrete choice experiment by Veldwijk, Jorien, Lambooij, Mattijs S, Kallenberg, Frank G J, van Kranen, Henk J, Bredenoord, Annelien L, Dekker, Evelien, Smit, Henriëtte A, de Wit, G Ardine

“…This study explored individuals' preferences for genetic testing for colorectal cancer (CRC) in a screening situation and their willingness to participate in…”
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Mismatch repair protein Msh2 contributes to UVB-induced cell cycle arrest in epidermal and cultured mouse keratinocytes by van Oosten, Marijke, Stout, Gerdine J, Backendorf, Claude, Rebel, Heggert, de Wind, Niels, Darroudi, Firouz, van Kranen, Henk J, de Gruijl, Frank R, Mullenders, Leon HF

“…Nucleotide excision repair (NER), cell cycle regulation and apoptosis are major defence mechanisms against the carcinogenic effects of UVB radiation. NER…”
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Opposing associations of serum n‐3 and n‐6 polyunsaturated fatty acids with colorectal adenoma risk: An endoscopy‐based case–control study by Pot, Gerda K., Geelen, Anouk, van Heijningen, Else‐Mariëtte B., Siezen, Christine L.E., van Kranen, Henk J., Kampman, Ellen

“…Several human and animal studies have shown that n‐3 polyunsaturated fatty acids (PUFA) might be associated with a decreased risk, whereas other studies showed…”
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Comparative gene expression profiling in two congenic mouse strains following Bordetella pertussis infection by Banus, Sander, Vandebriel, Rob J, Pennings, Jeroen L A, Gremmer, Eric R, Wester, Piet W, van Kranen, Henk J, Breit, Timo M, Demant, Peter, Mooi, Frits R, Hoebee, Barbara, Kimman, Tjeerd G

“…Susceptibility to Bordetella pertussis infection varies widely. These differences can partly be explained by genetic host factors. HcB-28 mice are more…”
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UV-induced DNA damage, repair, mutations and oncogenic pathways in skin cancer by de Gruijl, Frank R, van Kranen, Henk J, Mullenders, Leon H.F

“…Repair of UV induced DNA damage is of key importance to UV-induced skin carcinogenesis. Specific signal transduction pathways that regulate cell cycling,…”
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Policy Making in Newborn Screening Needs a Structured and Transparent Approach by Jansen, Marleen E, Lister, Karla J, van Kranen, Henk J, Cornel, Martina C

“…Newborn bloodspot screening (NBS) programs have expanded significantly in the past years and are expected to expand further with the emergence of genetic…”
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Endogenous Sex Steroids and Risk of Cervical Carcinoma: Results from the EPIC Study by RINALDI, Sabina, PLUMMER, Martyn, LUKANOVA, Annekatrin, KAAKS, Rudolf, WEIKERT, Cornelia, BOEING, Heiner, TRICHOPOULOU, Antonia, LAGIOU, Pagona, TRICHOPOULOS, Dimitrios, PALLI, Domenico, AGNOLI, Claudia, TUMINO, Rosario, BIESSY, Carine, VINEIS, Paolo, PANICO, Salvatore, BUENO-DE-MESQUITA, Bas, VAN KRANEN, Henk J, HM PEETERS, Petra, BAKKEN, Kjersti, LUND, Eiliv, TORHILD GRAM, Inger, RODRIGUEZ, Laudina, XAVIER BOSCH, F, CASTELLSAGUE, Xavier, SANCHEZ, Maria-José, DORRONSORO, Miren, NAVARRO, Carmen, BARRICARTE GURREA, Aurelio, KJELLBERG, Lennart, DILLNER, Joakim, MANJER, Jonas, BUTT, Salma, KHAW, Kay-Tee, WAREHAM, Nicholas, OVERVAD, Kim, ALLEN, Naomi E, TRAVIS, Ruth, ROMIEU, Isabelle, FERRARI, Pietro, RIBOLI, Elio, FRANCESCHI, Silvia, KRUGER KJAER, Susanne, TJONNELAND, Anne, CLAVEL-CHAPELON, Françoise, CHABBERT-BUFFET, Nathalie, MESRINE, Sylvie

“…Epidemiologic data and animal models suggest that, despite the predominant role of human papillomavirus infection, sex steroid hormones are also involved in…”
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Specific polymorphisms in the vitamin D metabolism pathway are not associated with susceptibility to Chlamydia trachomatis infection in humans by Lanjouw, Esmée, Branković, Ivan, Pleijster, Jolein, Spaargaren, Joke, Hoebe, Christian J. P. A., van Kranen, Henk J., Ouburg, Sander, Morré, Servaas A.

“…Chlamydia trachomatis is the most common sexually transmitted bacterium worldwide. Its often asymptomatic course of infection increases chances of…”
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Relationship between UV-induced mutant p53 patches and skin tumours, analysed by mutation spectra and by induction kinetics in various DNA-repair-deficient mice by Rebel, Heggert, Kram, Nicolien, Westerman, Anja, Banus, Sander, van Kranen, Henk J., de Gruijl, Frank R.

“…Clusters of p53 immunopositive epidermal keratinocytes (so-called p53 patches, clones or foci) are found in sun or ultraviolet (UV) light-exposed skin. We…”
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Costs and health effects of adding functional foods containing phytosterols/-stanols to statin therapy in the prevention of cardiovascular disease by Eussen, Simone R.B.M., Feenstra, Talitha L., Toxopeus, Ido B., Hoekstra, Jeljer, Klungel, Olaf H., Verhagen, Hans, van Kranen, Henk J., Rompelberg, Cathy J.M.

“…The present modelling study aimed to evaluate if and by how much functional foods containing phytosterols/-stanols add to the benefits of statins in the…”
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Polymorphisms in the genes involved in the arachidonic acid‐pathway, fish consumption and the risk of colorectal cancer by Siezen, Christine L.E., Bueno‐de‐Mesquita, H. Bas, Peeters, Petra H.M., Kram, Nicolien R., van Doeselaar, Marina, van Kranen, Henk J.

“…The objective of this study on colorectal cancer was to investigate the associations between SNPs in the genes involved in the arachidonic acid (AA)‐pathway,…”
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Lignan Precursors From Flaxseed or Rye Bran Do Not Protect Against the Development of Intestinal Neoplasia in ApcMin Mice by Kranen, Henk J. van, Mortensen, Alicja, Sorensen, Ilona K, Berg-Wijnands, Jolanda van den, Beems, Rudolf, Nurmi, Tarja, Adlercreutz, Herman, Kreijl, Coen F. van

“…Phytoestrogens, like isoflavonoids and lignans, have been postulated as possible colorectal cancer protective constituents. To investigate this hypothesis, two…”
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Colorectal adenoma risk is modified by the interplay between polymorphisms in arachidonic acid pathway genes and fish consumption by Siezen, Christine L.E., van Leeuwen, Astrid I.M., Kram, Nicolien R., Luken, Manon E.M., van Kranen, Henk J., Kampman, Ellen

“…Associations between polymorphisms in genes (SNPs) involved in the arachidonic acid (AA) pathway and colorectal adenomas have been investigated in a Dutch case…”
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Influence of the use of functional foods enriched with phytosterols/-stanols on adherence to statin therapy by Eussen, Simone R. B. M., Bouvy, Marcel L., Rompelberg, Cathy J. M., van der Elst, Menno E., Garssen, Johan, Oosterveld, Marco H., de Boer, Anthonius, de Gier, Johan J., van Kranen, Henk J., Klungel, Olaf H.

“…ABSTRACT Purpose Subjects using functional foods with approved health claims may be more likely to be non‐adherent with prescribed drug therapy. This study…”
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Estimated number of new cancer cases attributable to infection in the Netherlands in 2003 by van Lier, Elizabeth A, van Kranen, Henk J, van Vliet, Johannes A, Rahamat-Langendoen, Janna C

“…Abstract Several infectious diseases are considered to play a causal role in cancer aetiology. It is estimated that in 2003 in the Netherlands at maximum 2553…”
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Genetic variability of the fatty acid synthase pathway is not associated with prostate cancer risk in the European Prospective Investigation on Cancer (EPIC) by Campa, Daniele, Hüsing, Anika, Chang-Claude, Jenny, Dostal, Lucie, Boeing, Heiner, Kröger, Janine, Tjønneland, Anne, Roswall, Nina, Overvad, Kim, Dahm, Christina C, Rodríguez, Laudina, Sala, Núria, Pérez, Maria José Sánchez, Larrañaga, Nerea, Chirlaque, Maria-Dolores, Ardanaz, Eva, Khaw, Kay-Tee, Wareham, Nick, Allen, Naomi E, Travis, Ruth C, Trichopoulou, Antonia, Naska, Androniki, Bamia, Christina, Palli, Domenico, Sieri, Sabina, Tumino, Rosario, Sacerdote, Carlotta, van Kranen, Henk J, Bas Bueno-de-Mesquita, H, Stattin, Pär, Johansson, Mattias, Chajes, Veronique, Rinaldi, Sabina, Romieu, Isabelle, Siddiq, Afshan, Norat, Teresa, Riboli, Elio, Kaaks, Rudolf, Canzian, Federico

“…Abstract A western lifestyle, characterised by low rates of energy expenditure and a high-energy diet rich in animal protein, saturated fats and refined…”
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