Search Results - "van Kooyk, Y."

Using the glycan toolbox for pathogenic interventions and glycan immunotherapy by Li, RJ Eveline, van Vliet, Sandra J, van Kooyk, Y

“…[Display omitted] •There is multilevel complexity in glycan-induced immune modulation.•Lectin binding is dependent on glycan constitution and carrier…”
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Carbohydrates in allergy: from disease to novel immunotherapies by Keumatio Doungstop, B.C., van Vliet, S.J., van Ree, R., de Jong, E.C., van Kooyk, Y.

“…Respiratory allergic disorders are a global public health problem that are responsible for substantial morbidity and healthcare expenditure. Despite the…”
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Galectin-9 induced by dietary synbiotics is involved in suppression of allergic symptoms in mice and humans by de Kivit, S., Saeland, E., Kraneveld, A. D., van de Kant, H. J. G., Schouten, B., van Esch, B. C. A. M., Knol, J., Sprikkelman, A. B., van der Aa, L. B., Knippels, L. M. J., Garssen, J., van Kooyk, Y., Willemsen, L. E. M.

“…: Background: Prebiotic galacto‐ and fructo‐oligosaccharides (scGOS/lcFOS) resembling non‐digestible oligosaccharides in human milk reduce the development of…”
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The puzzling pathophysiology of frozen shoulders – a scoping review by Kraal, T., Lübbers, J., van den Bekerom, M. P. J., Alessie, J., van Kooyk, Y., Eygendaal, D., Koorevaar, R. C. T.

“…Purpose The pathophysiology of frozen shoulders is a complex and multifactorial process. The purpose of this review is to scope the currently available…”
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Liposome induction of CD8+ T cell responses depends on CD169+ macrophages and Batf3-dependent dendritic cells and is enhanced by GM3 inclusion by Grabowska, J., Affandi, A.J., van Dinther, D., Nijen Twilhaar, M.K., Olesek, K., Hoogterp, L., Ambrosini, M., Heijnen, D.A.M., Klaase, L., Hidalgo, A., Asano, K., Crocker, P.R., Storm, G., van Kooyk, Y., den Haan, J.M.M.

“…Cancer vaccines aim to efficiently prime cytotoxic CD8+ T cell responses which can be achieved by vaccine targeting to dendritic cells. CD169+ macrophages have…”
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Haematopoietic antigen-presenting cells in the human thymic cortex: evidence for a role in selection and removal of apoptotic thymocytes by Paessens, LC, Fluitsma, DM, van Kooyk, Y

“…Only a small proportion of thymocytes survive T cell selection in the thymus and leave the thymus as mature T cells. The vast majority of thymocytes undergo…”
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Nanobody-liposomes as novel cancer vaccine platform to efficiently stimulate T cell immunity by Bouma, R.G., Nijen Twilhaar, M.K., Brink, H.J., Affandi, A.J., Mesquita, B.S., Olesek, K., van Dommelen, J.M.A., Heukers, R., de Haas, A.M., Kalay, H., Ambrosini, M., Metselaar, J.M., van Rooijen, A., Storm, G., Oliveira, S., van Kooyk, Y., den Haan, J.M.M.

“…[Display omitted] •Liposomes can be decorated with DC-SIGN- or CD169-specific nanobodies.•Nanobody liposomes specifically bind to CD169+ and/or DC-SIGN+…”
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CNS myelin induces regulatory functions of DC-SIGN-expressing, antigen-presenting cells via cognate interaction with MOG by García-Vallejo, J J, Ilarregui, J M, Kalay, H, Chamorro, S, Koning, N, Unger, W W, Ambrosini, M, Montserrat, V, Fernandes, R J, Bruijns, S C M, van Weering, J R T, Paauw, N J, O'Toole, T, van Horssen, J, van der Valk, P, Nazmi, K, Bolscher, J G M, Bajramovic, J, Dijkstra, C D, 't Hart, B A, van Kooyk, Y

“…Myelin oligodendrocyte glycoprotein (MOG), a constituent of central nervous system myelin, is an important autoantigen in the neuroinflammatory disease…”
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In-depth immune profiling of peripheral blood mononuclear cells in pancreatic cancer patients by Zwart, E., Rodriguez, E., Verhoeff, J., Affandi, A., Meijer, L., De Kok, M., Garcia Vallejo, J., Mebius, R., Van Kooyk, Y., Kazemier, G.

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DC-SIGN: a novel HIV receptor on DCs that mediates HIV-1 transmission by Geijtenbeek, T B H, van Kooyk, Y

“…The dendritic cell (DC)-specific HIV-1 receptor DC-SIGN plays a key-role in the dissemination of HIV-1 by DCs. DC-SIGN captures HIV-1 at sites of entry,…”
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The mannose cap of mycobacterial lipoarabinomannan does not dominate the Mycobacterium–host interaction by Appelmelk, B. J., Den Dunnen, J., Driessen, N. N., Ummels, R., Pak, M., Nigou, J., Larrouy‐Maumus, G., Gurcha, S. S., Movahedzadeh, F., Geurtsen, J., Brown, E. J., Eysink Smeets, M. M., Besra, G. S., Willemsen, P. T. J., Lowary, T. L., Van Kooyk, Y., Maaskant, J. J., Stoker, N. G., Van Der Ley, P., Puzo, G., Vandenbroucke‐Grauls, C. M. J. E., Wieland, C. W., Van Der Poll, T., Geijtenbeek, T. B. H., Van Der Sar, A. M., Bitter, W.

“…Summary Pathogenic mycobacteria have the ability to persist in phagocytic cells and to suppress the immune system. The glycolipid lipoarabinomannan (LAM), in…”
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The Small GTPase, Rap1, Mediates CD31-Induced Integrin Adhesion by Reedquist, Kris A., Ross, Ewan, Koop, Elianne A., Rob M. F. Wolthuis, Fried J. T. Zwartkruis, van Kooyk, Yvette, Salmon, Mike, Buckley, Christopher D., Bos, Johannes L.

“…Integrin-mediated leukocyte adhesion is a critical aspect of leukocyte function that is tightly regulated by diverse stimuli, including chemokines, antigen…”
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A dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN)-related protein is highly expressed on human liver sinusoidal endothelial cells and promotes HIV-1 infection by Bashirova, A A, Geijtenbeek, T B, van Duijnhoven, G C, van Vliet, S J, Eilering, J B, Martin, M P, Wu, L, Martin, T D, Viebig, N, Knolle, P A, KewalRamani, V N, van Kooyk, Y, Carrington, M

“…The discovery of dendritic cell (DC)-specific intercellular adhesion molecule (ICAM)-3-grabbing nonintegrin (DC-SIGN) as a DC-specific ICAM-3 binding receptor…”
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Molecular Basis of the Differences in Binding Properties of the Highly Related C-type Lectins DC-SIGN and L-SIGN to Lewis X Trisaccharide and Schistosoma mansoni Egg Antigens by Van Liempt, Ellis, Imberty, Anne, Bank, Christine M.C., Van Vliet, Sandra J., Van Kooyk, Yvette, Geijtenbeek, Teunis B.H., Van Die, Irma

“…The dendritic cell-specific C-type lectin DC-SIGN functions as a pathogen receptor that recognizes Schistosoma mansoni egg antigens through its major glycan…”
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Pathogens use carbohydrates to escape immunity induced by dendritic cells by Kooyk, Yvette van, Engering, Anneke, Lekkerkerker, Annemarie N, Ludwig, Irene S, Geijtenbeek, Teunis BH

“…Dendritic cells (DCs) play a central role in balancing immune responses between tolerance induction and immune activation. Under steady state conditions DCs…”
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Increased expression of DC‐SIGN+IL‐12+IL‐18+ and CD83+IL‐12–IL‐18– dendritic cell populations in the colonic mucosa of patients with Crohn's disease by Velde, Anje A. te, van Kooyk, Yvette, Braat, Henri, Hommes, Daan W., Dellemijn, Trees A. M., Slors, J. Frederik M., van Deventer, Sander J. H., Vyth‐Dreese, Florry A.

“…Dentritic cells (DC) as antigen‐presenting cells are most likely responsible for regulation of abnormal T cell activation in Crohn's disease (CD), a chronic…”
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Synovial dendritic cells in juvenile idiopathic arthritis (JIA) express receptor activator of NF‐κB (RANK) by Varsani, H., Patel, A., van Kooyk, Y., Woo, P., Wedderburn, L. R.

“…Objectives. To analyse the expression of receptor activator of NF‐κB (RANK) and RANK ligand (RANKL) in the joints of children with juvenile idiopathic…”
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Enhancement of LFA-1-mediated cell adhesion by triggering through CD2 or CD3 on T lymphocytes by van Kooyk, Y, van de Wiel-van Kemenade, P, Weder, P, Kuijpers, T. W, Figdor, C. G

“…The lymphocyte function-associated molecule LFA-1 (CD11a/CD18) plays a key part in lymphocyte adhesion. Lymphocytes do not adhere spontaneously; activation of…”
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MEMD, a new cell adhesion molecule in metastasizing human melanoma cell lines, is identical to ALCAM (activated leukocyte cell adhesion molecule) by Degen, WG, van Kempen, LC, Gijzen, EG, van Groningen, JJ, van Kooyk, Y, Bloemers, HP, Swart, GW

“…From a differential mRNA display comparing a non- and a highly metastasizing human melanoma cell line, we isolated and characterized memD. memD is…”
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Synovial dendritic cells in juvenile idiopathic arthritis (JIA) express receptor activator of NF-[kappa]B (RANK) by Varsani, H, Patel, A, Y. van Kooyk, Woo, P, Wedderburn, L R

“…Objectives. To analyse the expression of receptor activator of NF-[kappa]B (RANK) and RANK ligand (RANKL) in the joints of children with juvenile idiopathic…”
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