Search Results - "van Kessel, Sebastiaan P."

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  1. 1

    Gut bacterial tyrosine decarboxylases restrict levels of levodopa in the treatment of Parkinson’s disease by van Kessel, Sebastiaan P., Frye, Alexandra K., El-Gendy, Ahmed O., Castejon, Maria, Keshavarzian, Ali, van Dijk, Gertjan, El Aidy, Sahar

    Published in Nature communications (18-01-2019)
    “…Human gut microbiota senses its environment and responds by releasing metabolites, some of which are key regulators of human health and disease. In this study,…”
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    Journal Article
  2. 2

    Parkinson's Disease Medication Alters Small Intestinal Motility and Microbiota Composition in Healthy Rats by van Kessel, Sebastiaan P, Bullock, Amber, van Dijk, Gertjan, El Aidy, Sahar

    Published in mSystems (22-02-2022)
    “…Parkinson's disease (PD) is known to be associated with altered gastrointestinal function and microbiota composition. To date, the effect of PD medication on…”
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  3. 3

    Gut bacterial tyrosine decarboxylase associates with clinical variables in a longitudinal cohort study of Parkinsons disease by van Kessel, Sebastiaan P., Auvinen, Petri, Scheperjans, Filip, El Aidy, Sahar

    Published in NPJ Parkinson's Disease (15-12-2021)
    “…Gut microbiota influences the clinical response of a wide variety of orally administered drugs. However, the underlying mechanisms through which…”
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  4. 4

    Bacillus subtilis SepF binds to the C-terminus of FtsZ by Król, Ewa, van Kessel, Sebastiaan P, van Bezouwen, Laura S, Kumar, Neeraj, Boekema, Egbert J, Scheffers, Dirk-Jan

    Published in PloS one (13-08-2012)
    “…Bacterial cell division is mediated by a multi-protein machine known as the "divisome", which assembles at the site of cell division. Formation of the divisome…”
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  5. 5

    High‐throughput CRISPRi phenotyping identifies new essential genes in Streptococcus pneumoniae by Liu, Xue, Gallay, Clement, Kjos, Morten, Domenech, Arnau, Slager, Jelle, van Kessel, Sebastiaan P, Knoops, Kèvin, Sorg, Robin A, Zhang, Jing‐Ren, Veening, Jan‐Willem

    Published in Molecular systems biology (01-05-2017)
    “…Genome‐wide screens have discovered a large set of essential genes in the opportunistic human pathogen Streptococcus pneumoniae . However, the functions of…”
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  6. 6

    Contributions of Gut Bacteria and Diet to Drug Pharmacokinetics in the Treatment of Parkinson's Disease by van Kessel, Sebastiaan P., El Aidy, Sahar

    Published in Frontiers in neurology (15-10-2019)
    “…Parkinson's disease is the second-most common neurodegenerative disorder worldwide. Besides deciphering the mechanisms that underlie the etiology of the…”
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  7. 7

    Gut bacterial deamination of residual levodopa medication for Parkinson’s disease by van Kessel, Sebastiaan P, de Jong, Hiltje R, Winkel, Simon L, van Leeuwen, Sander S, Nelemans, Sieger A, Permentier, Hjalmar, Keshavarzian, Ali, El Aidy, Sahar

    Published in BMC biology (20-10-2020)
    “…Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by both motor and non-motor symptoms. Gastrointestinal tract dysfunction is…”
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  8. 8

    Bacterial Metabolites Mirror Altered Gut Microbiota Composition in Patients with Parkinson's Disease by van Kessel, Sebastiaan P, El Aidy, Sahar

    Published in Journal of Parkinson's disease (01-01-2019)
    “…Increasing evidence is supporting the hypothesis of α-synuclein pathology spreading from the gut to the brain although the exact etiology of Parkinson's…”
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    Journal Article