Search Results - "van Kessel, Sebastiaan P."
-
1
Gut bacterial tyrosine decarboxylases restrict levels of levodopa in the treatment of Parkinson’s disease
Published in Nature communications (18-01-2019)“…Human gut microbiota senses its environment and responds by releasing metabolites, some of which are key regulators of human health and disease. In this study,…”
Get full text
Journal Article -
2
Parkinson's Disease Medication Alters Small Intestinal Motility and Microbiota Composition in Healthy Rats
Published in mSystems (22-02-2022)“…Parkinson's disease (PD) is known to be associated with altered gastrointestinal function and microbiota composition. To date, the effect of PD medication on…”
Get full text
Journal Article -
3
Gut bacterial tyrosine decarboxylase associates with clinical variables in a longitudinal cohort study of Parkinsons disease
Published in NPJ Parkinson's Disease (15-12-2021)“…Gut microbiota influences the clinical response of a wide variety of orally administered drugs. However, the underlying mechanisms through which…”
Get full text
Journal Article -
4
Bacillus subtilis SepF binds to the C-terminus of FtsZ
Published in PloS one (13-08-2012)“…Bacterial cell division is mediated by a multi-protein machine known as the "divisome", which assembles at the site of cell division. Formation of the divisome…”
Get full text
Journal Article -
5
High‐throughput CRISPRi phenotyping identifies new essential genes in Streptococcus pneumoniae
Published in Molecular systems biology (01-05-2017)“…Genome‐wide screens have discovered a large set of essential genes in the opportunistic human pathogen Streptococcus pneumoniae . However, the functions of…”
Get full text
Journal Article -
6
Contributions of Gut Bacteria and Diet to Drug Pharmacokinetics in the Treatment of Parkinson's Disease
Published in Frontiers in neurology (15-10-2019)“…Parkinson's disease is the second-most common neurodegenerative disorder worldwide. Besides deciphering the mechanisms that underlie the etiology of the…”
Get full text
Journal Article -
7
Gut bacterial deamination of residual levodopa medication for Parkinson’s disease
Published in BMC biology (20-10-2020)“…Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by both motor and non-motor symptoms. Gastrointestinal tract dysfunction is…”
Get full text
Journal Article -
8
Bacterial Metabolites Mirror Altered Gut Microbiota Composition in Patients with Parkinson's Disease
Published in Journal of Parkinson's disease (01-01-2019)“…Increasing evidence is supporting the hypothesis of α-synuclein pathology spreading from the gut to the brain although the exact etiology of Parkinson's…”
Get more information
Journal Article