Search Results - "van Kampen, J J A"
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An evaluation of COVID-19 serological assays informs future diagnostics and exposure assessment
Published in Nature communications (06-07-2020)“…The world is entering a new era of the COVID-19 pandemic in which there is an increasing call for reliable antibody testing. To support decision making on the…”
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Current Perspectives on the Management of Herpesvirus Infections in Solid Organ Transplant Recipients
Published in Viruses (01-07-2023)“…Solid organ transplant recipients (SOTRs) are at high risk of human herpesvirus (HHV)-related morbidity and mortality due to the use of immunosuppressive…”
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Targeted proteomics as a tool to detect SARS-CoV-2 proteins in clinical specimens
Published in PloS one (11-11-2021)“…The rapid, sensitive and specific detection of SARS-CoV-2 is critical in responding to the current COVID-19 outbreak. In this proof-of-concept study, we…”
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Selective cell death in HIV-1-infected cells by DDX3 inhibitors leads to depletion of the inducible reservoir
Published in Nature communications (30-04-2021)“…An innovative approach to eliminate HIV-1-infected cells emerging out of latency, the major hurdle to HIV-1 cure, is to pharmacologically reactivate viral…”
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Inter-Laboratory Reproducibility of Inducible HIV-1 Reservoir Quantification by TILDA
Published in Viruses (02-09-2020)“…Substantial efforts to eliminate or reduce latent HIV-1 reservoirs are underway in clinical trials and have created a critical demand for sensitive, accurate,…”
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Genetic Features of HIV-1 Integrase Sub-Subtype A6 Predominant in Russia and Predicted Susceptibility to INSTIs
Published in Viruses (31-07-2020)“…The increasing use of the integrase strand transfer inhibitor (INSTI) class for the treatment of HIV-infection has pointed to the importance of analyzing the…”
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Duration and key determinants of infectious virus shedding in hospitalized patients with coronavirus disease-2019 (COVID-19)
Published in Nature communications (11-01-2021)“…Key questions in COVID-19 are the duration and determinants of infectious virus shedding. Here, we report that infectious virus shedding is detected by virus…”
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Viruses as Sole Causative Agents of Severe Acute Respiratory Tract Infections in Children
Published in PloS one (10-03-2016)“…Respiratory syncytial virus (RSV) and influenza A viruses are known to cause severe acute respiratory tract infections (SARIs) in children. For other viruses…”
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Prevalence of Intrathecal Acyclovir Resistant Virus in Herpes Simplex Encephalitis Patients
Published in PloS one (12-05-2016)“…Herpes simplex encephalitis (HSE) is a life-threatening complication of herpes simplex virus (HSV) infection. Acyclovir (ACV) is the antiviral treatment of…”
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Quantitative Analysis of Antiretroviral Drugs in Lysates of Peripheral Blood Mononuclear Cells Using MALDI-Triple Quadrupole Mass Spectrometry
Published in Analytical chemistry (Washington) (01-07-2008)“…We report here on the use of a prototype matrix-assisted laser desorption/ionization (MALDI)-triple quadrupole mass spectrometer for quantitative analysis of…”
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Small quantities of respiratory syncytial virus RNA only in large droplets around infants hospitalized with acute respiratory infections
Published in Antimicrobial resistance & infection control (30-06-2021)“…Respiratory syncytial virus (RSV) is a major cause of respiratory tract infections in young children. The predominant transmission routes for RSV are still a…”
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High Levels of Neutrophil Extracellular Traps Persist in the Lower Respiratory Tract of Critically Ill Patients With Coronavirus Disease 2019
Published in The Journal of infectious diseases (20-05-2021)“…Abstract Lower respiratory tract (LRT) disease induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can deteriorate to acute respiratory…”
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Qualitative and Quantitative Analysis of Pharmaceutical Compounds by MALDI-TOF Mass Spectrometry
Published in Analytical chemistry (Washington) (01-08-2006)“…In this report, we discuss key issues for the successful application of MALDI-TOF mass spectrometry to quantify drugs. These include choice and preparation of…”
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Hematopoietic stem cell transplantation using single UM171-expanded cord blood: a single-arm, phase 1–2 safety and feasibility study
Published in The Lancet. Haematology (01-02-2020)“…Benefits of cord blood transplantation include low rates of relapse and chronic graft-versus-host disease (GVHD). However, the use of cord blood is rapidly…”
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Ultrafast and high-throughput mass spectrometric assay for therapeutic drug monitoring of antiretroviral drugs in pediatric HIV-1 infection applying dried blood spots
Published in Analytical and bioanalytical chemistry (01-09-2010)“…Kaletra® (Abott Laboratories) is a co-formulated medication used in the treatment of HIV-1-infected children, and it contains the two antiretroviral protease…”
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Quantitative Analysis of HIV-1 Protease Inhibitors in Cell Lysates Using MALDI-FTICR Mass Spectrometry
Published in Analytical chemistry (Washington) (15-05-2008)“…In this report we explore the use of MALDI-FTICR mass spectrometry for the quantitative analysis of five HIV-1 protease inhibitors in cell lysates…”
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Ultra-fast analysis of plasma and intracellular levels of HIV protease inhibitors in children: a clinical application of MALDI mass spectrometry
Published in PloS one (01-07-2010)“…HIV protease inhibitors must penetrate into cells to exert their action. Differences in the intracellular pharmacokinetics of these drugs may explain why some…”
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Emergence and Potential Extinction of Genetic Lineages of Human Metapneumovirus between 2005 and 2021
Published in mBio (28-02-2023)“…Human metapneumovirus (HMPV) is one of the leading causes of respiratory illness (RI), primarily in infants. Worldwide, two genetic lineages (A and B) of HMPV…”
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Determination of the antiretroviral drug tenofovir in plasma from HIV-infected adults by ultrafast isotope dilution MALDI-triple quadrupole tandem mass spectrometry
Published in Journal of mass spectrometry. (01-03-2011)“…A new and reliable mass spectrometric method using an isotope dilution method in combination with matrix‐assisted laser desorption/ionization‐triple quadrupole…”
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Miscarriage Associated with Zika Virus Infection
Published in The New England journal of medicine (08-09-2016)“…A 31-year-old woman who was 10 weeks pregnant contracted Zika virus infection in Suriname; this led to fetal loss. ZIKV was detected in the woman's blood for…”
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