Search Results - "van Iersel, Marlou L. P. S"

A Population Pharmacokinetic Model for a Solid Oral Tablet Formulation of Posaconazole by van Iersel, Marlou L P S, Rossenu, Stefaan, de Greef, Rik, Waskin, Hetty

“…A delayed-release solid tablet formulation that releases posaconazole in the small intestine was developed to maximize systemic absorption. This study aimed to…”
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Phase 1b study of new posaconazole tablet for prevention of invasive fungal infections in high-risk patients with neutropenia by Duarte, Rafael F, López-Jiménez, Javier, Cornely, Oliver A, Laverdiere, Michel, Helfgott, David, Haider, Shariq, Chandrasekar, Pranatharthi, Langston, Amelia, Perfect, John, Ma, Lei, van Iersel, Marlou L P S, Connelly, Nancy, Kartsonis, Nicholas, Waskin, Hetty

“…Posaconazole tablets, a new oral formulation of posaconazole, can be effective when given as antifungal prophylaxis to neutropenic patients at high risk for…”
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Posaconazole Tablet Pharmacokinetics: Lack of Effect of Concomitant Medications Altering Gastric pH and Gastric Motility in Healthy Subjects by KRAFT, Walter K, CHANG, Peter S, VAN LERSEL, Marlou L. P. S, WASKIN, Hetty, KRISHNA, Gopal, KERSEMAEKERS, Wendy M

“…Posaconazole oral suspension is an extended-spectrum triazole that should be taken with food to maximize absorption. A new posaconazole tablet formulation has…”
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Regioselectivity of Phase II Metabolism of Luteolin and Quercetin by UDP-Glucuronosyl Transferases by Boersma, Marelle G, van der Woude, Hester, Bogaards, Jan, Boeren, Sjef, Vervoort, Jacques, Cnubben, Nicole H. P, van Iersel, Marlou L. P. S, van Bladeren, Peter J, Rietjens, Ivonne M. C. M

“…The regioselectivity of phase II conjugation of flavonoids is expected to be of importance for their biological activity. In the present study, the…”
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Pharmacokinetics and safety study of posaconazole intravenous solution administered peripherally to healthy subjects by Kersemaekers, Wendy M, van Iersel, Thijs, Nassander, Ulla, O'Mara, Edward, Waskin, Hetty, Caceres, Maria, van Iersel, Marlou L P S

“…This study evaluated the safety, tolerability, and pharmacokinetics of a posaconazole i.v. (intravenous) solution. This was a single-center, 2-part,…”
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Effect of a high-fat meal on the pharmacokinetics of 300-milligram posaconazole in a solid oral tablet formulation by Kersemaekers, Wendy M, Dogterom, Peter, Xu, Jialin, Marcantonio, Eugene E, de Greef, Rik, Waskin, Hetty, van Iersel, Marlou L P S

“…Posaconazole in oral suspension must be taken multiple times a day with food (preferably a high-fat meal) to ensure adequate exposure among patients. We…”
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Erratum for Kersemaekers et al., Pharmacokinetics and Safety Study of Posaconazole Intravenous Solution Administered Peripherally to Healthy Subjects by Kersemaekers, Wendy M, van Iersel, Thijs, Nassander, Ulla, O'Mara, Edward, Waskin, Hetty, Caceres, Maria, van Iersel, Marlou L P S

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Inhibition of human glutathione S-transferase P1-1 by the flavonoid quercetin by van Zanden, Jelmer J., Ben Hamman, Omar, van Iersel, Marlou L.P.S., Boeren, Sjef, Cnubben, Nicole H.P., Lo Bello, Mario, Vervoort, Jacques, van Bladeren, Peter J., Rietjens, Ivonne M.C.M.

“…In the present study, the inhibition of human glutathione S-transferase P1-1 (GSTP1-1) by the flavonoid quercetin has been investigated. The results show a…”
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Structure activity relationships for the chemical behaviour and toxicity of electrophilic quinones/quinone methides by Rietjens, I M, Awad, H M, Boersma, M G, van Iersel, M L, Vervoort, J, Van Bladeren, P J

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Interactions of α,β-Unsaturated Carbonyl Compounds with the Glutathione-Related Biotransformation System by van Iersel, Marlou L. P. S

“…The research described in this thesis focuses on interactions of α,β-unsaturated carbonyl compounds with various parts of the glutathione-related…”
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