Search Results - "van Hove, L."
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Neurotrophic factors and neuroplasticity pathways in the pathophysiology and treatment of depression
Published in Psychopharmacology (01-08-2018)“…Depression is a major health problem with a high prevalence and a heavy socioeconomic burden in western societies. It is associated with atrophy and impaired…”
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2
Quantifying urban heat island effects and human comfort for cities of variable size and urban morphology in the Netherlands
Published in Journal of Geophysical Research (2011)“…This paper reports on the canopy layer urban heat island (UHI) and human comfort in a range of small to large cities and villages in the Netherlands. To date,…”
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3
Bora phosphorylation substitutes in trans for T-loop phosphorylation in Aurora A to promote mitotic entry
Published in Nature communications (26-03-2021)“…Polo-like kinase 1 (Plk1) is instrumental for mitotic entry and progression. Plk1 is activated by phosphorylation on a conserved residue Thr210 in its…”
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Predictors and consequences of non-suicidal self-injury in relation to life, peer, and school factors
Published in Journal of adolescence (London, England.) (01-07-2021)“…Numerous life, peer, and school-related factors have been found to be associated with non-suicidal self-injury (NSSI) among adolescents; however, most studies…”
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5
Seasonal dependence of the urban heat island on the street canyon aspect ratio
Published in Quarterly journal of the Royal Meteorological Society (01-10-2014)“…In this article we study the relation between the urban heat island (UHI) in the urban canyon and street geometry, in particular the aspect ratio. Model…”
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6
Mitochondrial calcium uniporter stabilization preserves energetic homeostasis during Complex I impairment
Published in Nature communications (19-05-2022)“…Calcium entering mitochondria potently stimulates ATP synthesis. Increases in calcium preserve energy synthesis in cardiomyopathies caused by mitochondrial…”
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7
The Impact of Sample Storage on Blood Methylation: Towards Assessing Myelin Gene Methylation as a Biomarker for Progressive Multiple Sclerosis
Published in International journal of molecular sciences (01-03-2024)“…One of the major challenges in multiple sclerosis (MS) is to accurately monitor and quantify disability over time. Thus, there is a pressing need to identify…”
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The behavioral phenotype of children and adolescents with attenuated non-ketotic hyperglycinemia, intermediate to good subtype
Published in Orphanet journal of rare diseases (08-04-2024)“…We aim to describe the behavioral phenotype of children and adolescents with the good to intermediate attenuated form of non-ketotic hyperglycinemia (NKH) and…”
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Pathogenic variants in SQOR encoding sulfide:quinone oxidoreductase are a potentially treatable cause of Leigh disease
Published in Journal of inherited metabolic disease (01-09-2020)“…Hydrogen sulfide, a signaling molecule formed mainly from cysteine, is catabolized by sulfide:quinone oxidoreductase (gene SQOR). Toxic hydrogen sulfide…”
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10
Identification of a novel biomarker for pyridoxine‐dependent epilepsy: Implications for newborn screening
Published in Journal of inherited metabolic disease (01-05-2019)“…Pyridoxine‐dependent epilepsy (PDE) is often characterized as an early onset epileptic encephalopathy with dramatic clinical improvement following pyridoxine…”
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11
Interplay of Impaired Cellular Bioenergetics and Autophagy in PMM2-CDG
Published in Genes (04-08-2023)“…Congenital disorders of glycosylation (CDG) and mitochondrial disorders are multisystem disorders with overlapping symptomatology. Pathogenic variants in the…”
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Prediction of long-term outcome in glycine encephalopathy: a clinical survey
Published in Journal of inherited metabolic disease (01-03-2012)“…Objective Glycine encephalopathy (GE) is a rare autosomal recessive inborn error of glycine degradation resulting in severe encephalopathy with ensuing poor…”
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Targeted Methylation Profiling of Single Laser-Capture Microdissected Post-Mortem Brain Cells by Adapted Limiting Dilution Bisulfite Pyrosequencing (LDBSP)
Published in International journal of molecular sciences (08-12-2022)“…A reoccurring issue in neuroepigenomic studies, especially in the context of neurodegenerative disease, is the use of (heterogeneous) bulk tissue, which…”
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Author Correction: Mitochondrial calcium uniporter stabilization preserves energetic homeostasis during Complex I impairment
Published in Nature communications (20-06-2022)Get full text
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15
Ketogenic diet as a glycine lowering therapy in nonketotic hyperglycinemia and impact on brain glycine levels
Published in Orphanet journal of rare diseases (05-12-2022)“…Nonketotic hyperglycinemia (NKH) is a severe neurometabolic disorder characterized by increased glycine levels. Current glycine reduction therapy uses high…”
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Correction: Ketogenic diet as a glycine lowering therapy in nonketotic hyperglycinemia and impact on brain glycine levels
Published in Orphanet journal of rare diseases (13-03-2023)Get full text
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Prenatal stress and early-life exposure to fluoxetine have enduring effects on anxiety and hippocampal BDNF gene expression in adult male offspring
Published in Developmental psychobiology (01-05-2016)“…ABSTRACT With the growing use of selective serotonin reuptake inhibitor medications (SSRIs) for the treatment of depression during the perinatal period,…”
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Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer's disease
Published in Clinical epigenetics (21-03-2019)“…Alzheimer's disease is a progressive neurodegenerative disorder that is hypothesized to involve epigenetic dysfunction. Previous studies of DNA modifications…”
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19
genotypic and phenotypic spectrum of pyridoxine-dependent epilepsy due to mutations in ALDH7A1
Published in Journal of inherited metabolic disease (01-10-2010)“…Pyridoxine-dependent epilepsy is a disorder associated with severe seizures that may be caused by deficient activity of α-aminoadipic semialdehyde…”
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Fluoxetine during development reverses the effects of prenatal stress on depressive-like behavior and hippocampal neurogenesis in adolescence
Published in PloS one (01-09-2011)“…Depression during pregnancy and the postpartum period is a growing health problem, which affects up to 20% of women. Currently, selective serotonin reuptake…”
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